Robot

UW microbiologists discovered a bacterial toxin that, when engineered, is a key part of a gene editor that can make single-base changes in human mitochondria. The genome in mitochondria — the cell’s energy-producing organelles — is involved in disease and key biological functions, and the ability to precisely alter this […]

Changes in a few small molecules involved in a cell’s metabolism seem to indicate whether a restricted “life extension” diet will actually extend, shorten, or have no effect on lifespan, a study of fruit flies has found. The findings suggest that analyzing the level of small molecules in cells, an […]

A research team from Yale and Baylor College of Medicine has completed the largest single-cell analysis to date of lungs affected by Idiopathic Pulmonary Fibrosis (IPF), revealing how cells change in response to the disease and identifying previously unknown cell types. The findings, published in the issue of Science Advances, deepen […]

There are innumerable studies showing small gains in mouse life span. Most cannot be reproduced, particularly the older ones, those that took place before it was common knowledge in the research community that one has to very aggressively control for accidental calorie restriction. If an intervention makes mice eat less, […]

In recent years academic interest has grown in the study of the gut microbiome. Researchers are making inroads into understanding the considerable influence of these microbial populations over the progression of health and aging. The gut microbiome may be as influential as physical activity in these matters. The balance of […]

Emory University researchers have shown that Zika virus infection soon after birth leads to long-term brain and behavior problems, including persistent socioemotional, cognitive and motor deficits, as well as abnormalities in brain structure and function. This study is one of the first to shed light on the potential long-term effects […]

A novel study from the Institute of Environmental Medicine at Karolinska Institutet indicates that antibodies against a small lipid entity, phosphorylcholine (PC), can be associated with protection in inflammatory systemic diseases, including SLE and Sjögren´s syndrome. The results support evidence for a potential treatment by providing antibodies (anti-PC) to patients […]

A sizable portion of the variable efficacy of first generation stem cell therapies as presently practiced may be due to a poor quality of cells following expansion in culture. Regardless of quality, near all such cells die shortly after transplantation. Few clinics and few approaches to cell therapy lead to […]

Why do we age? What exactly happens in the body? And: Can something be done about it? These are questions that have occupied science since time immemorial. The pharmacists Alexandra K. Kiemer and Jessica Hoppstädter from the Saarland University have not found a philosophical stone. But: they have uncovered processes […]

Everyone is aging – time is not choosing its victims. You start of young and beautiful and energized, but eventually your body and mind start falling behind and you have to retire. But when would be an appropriate time to retire? Scientists from the Newcastle University say that 50 year […]

Aichi Cancer Center(1) and NEC Corporation (NEC; 6701) today announced the launch of fundamental research aiming to realize the promise of advanced personalized cancer immunotherapy by improving the performance of NEC's neoantigen prediction system and developing predictive biomarkers for patient stratification through the fusion of AI and experimental immunology. This […]

Eating black raspberries might reduce inflammation associated with skin allergies, a new study indicates. In a study done with mice and published earlier in the journal Nutrients, researchers found that a diet high in black raspberries reduced inflammation from contact hypersensitivity – a condition that causes redness and inflammation in […]