July 19, 2018

Research Brief: Social stress linked to disease of aging and shortened lifespan

Society is becoming older and more vulnerable to chronic diseases that result in a poor quality of life. Life stress, which before being a scientific notion is instinctively clear to most due to its universality, is an important risk factor promoting the vulnerability to disease. So far, there is limited […]
July 19, 2018

Link found between bitter-taste sensitivity and cancer risk

High bitter-taste sensitivity is associated with a significantly increased risk of cancer in older British women, according to researchers who conducted a unique study of 5,500 women whose diet, lifestyle and health has been tracked for about 20 years. The research examined the relationship between the ability to taste the […]
July 18, 2018

Magnetized wire could be used to detect cancer in people

A magnetic wire used to snag scarce and hard-to-capture tumor cells could prove to be a swift and effective tactic for early cancer detection, according to a study by researchers at the Stanford University School of Medicine. The wire, which is threaded into a vein, attracts special magnetic nanoparticles engineered to […]
July 18, 2018

NIH and Prostate Cancer Foundation launch large study on aggressive prostate cancer in African-American men

The largest coordinated research effort to study biological and non-biological factors associated with aggressive prostate cancer in African-American men has begun. The $26.5 million study is called RESPOND, or Research on Prostate Cancer in Men of African Ancestry: Defining the Roles of Genetics, Tumor Markers, and Social Stress. It will […]
July 18, 2018

Childhood stress leaves lasting mark on genes

Kids who experience severe stress are more likely to develop a host of physical and mental health problems by the time they reach adulthood, including anxiety, depression and mood disorders. But how does early life stress put children at risk when they grow up? To find out, researchers from the […]
July 18, 2018

Devastating disease of the lung is a new research gift’s focus

The lungs are made up of some 30 to 40 different types of cells. “When you get sick, these cells can change. New cells can come in and resident cells can change over,” says Naftali Kaminski, MD, Boehringer Ingelheim Pharmaceuticals, Inc., Endowed Professor of Medicine (Pulmonary), and chief of the […]
July 18, 2018

Deciphering dementia’s gender gap

Two-thirds of the 5.5 million Americans with Alzheimer’s disease are women, and without effective prevention and treatments, that number will triple by 2050. Now, thanks to an innovative partnership, two UCI researchers have been awarded $100,000 to dig into why such a huge gender disparity exists. Sunil Gandhi and Mathew […]
July 18, 2018

Yale-developed test for Alzheimer’s disease directly measures synaptic loss

Yale researchers have tested a new method for directly measuring synaptic loss in individuals with Alzheimer’s disease. The method, which uses PET imaging technology to scan for a specific protein in the brain linked to synapses, has the potential to accelerate research for new Alzheimer’s treatments, the researchers said. The […]
July 18, 2018

Protein found to be key component in irregularly excited brain cells

Researchers have identified a key protein involved in the irregular brain cell activity seen in autism spectrum disorders and epilepsy. The protein, p53, is well-known in cancer biology as a tumor suppressor. The findings, reported in the journal Human Molecular Genetics and Neuropharmacology, will open new avenues for understanding the […]
July 18, 2018

High Vinculin Levels Help Keep Aging Fruit Fly Hearts Young

Our cells tend to lose their shape as we grow older, contributing to many of the effects we experience as aging. This poses particular problems for the heart, where aging can disrupt the protein network within muscle cells that move blood around the body. A new discovery in how heart […]
July 17, 2018

Yale cancer researchers suggest new treatment for rare inherited cancers

Studying two rare inherited cancer syndromes, Yale Cancer Center (YCC) scientists have found the cancers are driven by a breakdown in how cells repair their DNA. The discovery, published in Nature Genetics, suggests a promising strategy for treatment with drugs recently approved for other forms of cancer, said the researchers. The two conditions […]
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