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Artificial intelligence model improves prediction six-fold. It’s one thing to detect sites in the genome associated with mental disorders; it’s quite another to discover the biological mechanisms by which these changes in DNA work in the human brain to boost risk. In their first concerted effort to tackle the latter, […]

Experts studying the evolutionary differentiation of organisms into male and female sexes have identified a very small sex chromosomal region called “OSU” in the first male-like green alga. They found OSU by comparing the whole genome sequences of two different types of algae from immediately before and after the evolution […]

Researchers at the University of Virginia School of Medicine have made a discovery about human papillomavirus, or HPV for short, that could lead to new treatments for cervical cancer and other cancers caused by the virus. HPV is responsible for nearly all cases of cervical cancer and 95 percent of anal cancers. It is the most common […]

New research on remyelination, the spontaneous regeneration of the brain’s fatty insulator that keeps neurons communicating, could lead to a novel approach to developing treatments for multiple sclerosis (MS) and other inflammatory diseases. The pre-clinical findings published in Cell Reports by a University at Buffalo team reveal that activation of a specific […]

Among the major challenges of studying Alzheimer’s disease and other dementia-related brain disorders: modeling and replicating the biological structures that play a huge role in those conditions. The pathological version of the tau protein, which is responsible for the neurofibrillary tangles present in the brains of those with any of […]

Recent breakthroughs in immunotherapy are making a huge difference in treating some forms of cancer, especially metastatic cancer. But breast cancer has proven a tricky foe for this new therapy, and an interdisciplinary team of FSU researchers is now a little bit closer to figuring out why. Associate Professor of […]

A selfish streak in genes known to drive species apart might occasionally bring them closer together, says a new study from the University of Nebraska-Lincoln and University of Rochester. Though the vast majority of genes are essential to organisms’ survival and reproduction, some selfishly turn against their counterparts to improve […]

Since the 1960s, scientists have known of a modification that occurs to a particular molecule in muscles, especially after exercise. What scientists haven’t known is how that modification happens, or even why. Now, in a serendipitous finding that started with seemingly unrelated work in viral infections, a team of Stanford […]

Women with polycystic ovary syndrome develop metabolic syndrome earlier than women without the condition—likely putting them at higher risk of developing diabetes and cardiovascular disease, according to a new study by the University of Michigan. Unlike other studies that examined polycystic ovary syndrome and metabolic syndrome at only one point […]

University of Tokyo researchers developed a novel approach to boost the effectiveness of a new type of vaccine. This approach is expected to be highly adaptable and boost the potential applications of new vaccines for personalized immunotherapy for cancer and prevention of emerging or re-emerging infectious diseases. Until now, so-called […]

Scientists identified two distinct control mechanisms in the developmental transition of undifferentiated stem cells into healthy brain cells. This fundamental research using mice may inform regenerative medicine treatments for neurodegenerative diseases and spinal cord injuries, in the future. When an embryo develops, stem cells differentiate into all the types of […]

Around the world, women outlive men. This is true in sickness and in health, in war and in peace, even during severe epidemics and famine. In most animal species, females live longer than males. Now, scientists at UC San Francisco have zeroed in on a possible genetic mechanism for this […]