January 17, 2018

Study suggests hope for a longer life for patients with rare autoimmune disorder

An unusual autoimmune disease that causes skin and lung damage can be treated effectively by stem cell transplant, a new study in the New England Journal of Medicine has found. The approach could represent the first new treatment to improve survival in patients with severe scleroderma in more than four decades. The experimental procedure […]
January 16, 2018

Catalyzing Research Innovation

An improved intracellular delivery system that can carry revolutionary gene-editing tools to stem cells, potentially curing diseases with genetic causes A method to increase prospects of successful births for couples undergoing in vitro fertilization, which currently fails 67 percent of the time The possibility that an effective drug treatment can […]
January 16, 2018

Biologists’ new peptide could fight many cancers

MIT biologists have designed a new peptide that can disrupt a key protein that many types of cancers, including some forms of lymphoma, leukemia, and breast cancer, need to survive. The new peptide targets a protein called Mcl-1, which helps cancer cells avoid the cellular suicide that is usually induced […]
January 16, 2018

Researchers Develop a Remote-Controlled Cancer Immunotherapy System

A team of researchers has developed an ultrasound-based system that can non-invasively and remotely control genetic processes in live immune T cells so that they recognize and kill cancer cells. There is a critical need to non-invasively and remotely manipulate cells at a distance, particularly for translational applications in animals […]
January 16, 2018

NIH researchers report first 3D structure of DHHC enzymes

The first three-dimensional structure of DHHC proteins — enzymes involved in many cellular processes, including cancer — explains how they function and may offer a blueprint for designing therapeutic drugs. Researchers have proposed blocking DHHC activity to boost the effectiveness of first-line treatments against common forms of lung and breast […]
January 15, 2018

Removing the Immunotherapy Blindfold

Immunotherapies are promising in theory, but often not in practice. In fact according to experts, they actually only work 10 percent of the time in the treatment of cancer – at best. Yet, while immunotherapy drugs may only help a minority of patients, those who do respond often do extremely well. […]
January 15, 2018

New research improves our understanding of cancer cell regulation

A team of cancer researchers from the University, has made an important contribution to our understanding of cancer cell regulation which could better inform future cancer treatments. The research is funded by North West Cancer Research, which has ring-fenced £180,000 for the three year-long project which started in 2015. Led by Professor […]
January 15, 2018

New immunotherapy approach boosts body’s ability to destroy cancer cells

Few cancer treatments are generating more excitement these days than immunotherapy—drugs based on the principle that the immune system can be harnessed to detect and kill cancer cells, much in the same way that it goes after infectious microorganisms. Yet these treatments only benefit some patients, and remain ineffective in […]
January 15, 2018

‘Decorated’ Stem Cells Could Offer Targeted Heart Repair

Although cardiac stem cell therapy is a promising treatment for heart attack patients, directing the cells to the site of an injury – and getting them to stay there – remains challenging. In a new pilot study using an animal model, North Carolina State University researcher Ke Cheng and his […]
January 15, 2018

New Polygenic Hazard Score Predicts When Men Develop Prostate Cancer

An international team, led by researchers at the University of California San Diego School of Medicine, has developed and validated a genetic tool for predicting age of onset of aggressive prostate cancer, a disease that kills more than 26,000 American men annually. The tool, described in the journal BMJ (formerly the British Medical […]
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