January 11, 2018

Discovery could help treat cancer more effectively

University of Alberta researchers have discovered a mechanism that may make cancer cells more susceptible to treatment. Post-doctoral fellow Mohammad Ali and his research team found that the protein RYBP prevents DNA repair in cancer cells, including breast cancer, which in turn could make chemo or radiation therapy more effective. […]
January 11, 2018

New stem cell method sheds light on a telltale sign of heart disease

While refining ways to grow arterial endothelial cells in the lab, a regenerative biology team at the Morgridge Institute for Research at the University of Wisconsin–Madison unexpectedly unearthed a powerful new model for studying a hallmark of vascular disease. The team, led by Morgridge Institute Fellow Dave Vereide, describes in the Jan. 9, […]
January 10, 2018

Stanford mechanical engineers give breast cancer research a boost

One of the most puzzling questions in breast cancer research is why some tumors stay put, while rogue cells from others break free and spread to surrounding tissues, the first step toward creating a more lethal disease. Although researchers have found some signs in mutated genes or telltale proteins on […]
January 9, 2018

Cancer targeted with reusable ‘stinging nettle’ treatment

Cancer cells can be destroyed more effectively and selectively with a unique new reusable treatment, activated with a substance found in stinging nettles and ants – thanks to new research by the University of Warwick.  Cancer cells killed more effectively and selectively with a new approach, using a substance found […]
January 9, 2018

Two UO chemistry projects shed new light on a cancer drug

One of the most widely used drugs to fight cancer could become more effective and safer, based on findings emerging from the lab of UO chemist Vickie DeRose. In two recently published papers, separate projects using different approaches and led by two of DeRose’s doctoral students have made new predictions for […]
January 8, 2018

Dirt-dwelling microbe produces potential anti-melanoma weapon

A type of soil-dwelling bacterium produces molecules that induce death in melanoma cells, research at Oregon State University shows. The molecule is a secondary metabolite, also known as a natural product, of Streptomyces bottropensis, and its properties are important because there are not many therapies that effectively manage melanoma, the […]
January 5, 2018

Supercharged antibiotics could turn tide against superbugs

An old drug supercharged by University of Queensland researchers has emerged as a new antibiotic that could destroy some of the world’s most dangerous superbugs. The supercharge technique , led by Dr Mark Blaskovich and Professor Matt Cooper from UQ’s Institute for Molecular Bioscience (IMB), potentially could revitalise other antibiotics. Antibiotic-resistant bacteria […]
January 5, 2018

Stem cell transplant for severe scleroderma improves survival, quality of life

New clinical trial findings show that a therapeutic regimen involving transplantation of a person’s own blood-forming stem cells can improve survival and quality of life for people with severe scleroderma, a life-threatening autoimmune disease. The regimen, known as myeloablative autologous hematopoietic stem cell transplant (HSCT), includes chemotherapy and total body […]
January 4, 2018

Cellular barcoding helps scientists understand the behavior of stem cells

By tagging bone marrow cells of mice with a genetic label, or barcode, researchers were able to track and describe the family tree of individual blood cells as they form in their natural environment. The scientists discovered that these cells regenerate differently than their counterparts do after a blood cell […]
January 4, 2018

Penn Engineers: Bone Marrow Transplant Stem Cells Can 'Swim' Upstream

When a cancer patient receives a bone marrow transplant, time is of the essence. Healthy stem cells, which can restart the production of blood cells and immune system components after a patient’s own are compromised, need to make their way from the circulatory system into the bones as quickly as […]
January 3, 2018

Unraveling the mechanisms that control cell growth and size

All living cells, from simple yeasts to human brain cells, regulate their rate of growth and their ultimate size and shape. How they do this, however, is one of the fundamental mysteries of biology. A new study, published in Current Biology, reveals a complex network of signals and feedback loops that control […]
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