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Parkinson’s disease is a neurodegenerative disorder that leads to progressive brain cell death and extensive loss of motor function. Despite much research being conducted on this disease, there are no definitive diagnostic tests currently available. Now, researchers report the identification of compounds that make up the signature odor of the […]

The terms “colon cancer” and “colorectal cancer” tend to be used interchangeably. But there are important differences between colon and rectal cancers. Less common and potentially more dangerous, rectal cancer calls for special expertise to properly diagnose and treat it. Karin Hardiman, M.D., Ph.D., surgical director of the Rogel Cancer Center’s Multidisciplinary […]

Eating a calcium-rich diet or taking calcium supplements does not appear to increase the risk of age-related macular degeneration (AMD), according to the findings of a study by scientists at the National Eye Institute (NEI). AMD is a leading cause of vision loss and blindness among people age 65 and […]

In research that casts cells as curators of their own history, Harvard Medical School researchers at Dana-Farber Cancer Institute have discovered that adult tissues retain a memory, inscribed on their DNA, of the embryonic cells from which they arose. The discovery led to one even more intriguing find—that the memory […]

Sperm is an incredibly good swimmer for its size. It needs quite a bit of strength to break through the cervical mucus barrier. But where does that strength come from? Scientists from the universities of York and Oxford say that the secret is the outer-layer which coats the tails of […]

One in three childhood cancer survivors is at risk of becoming infertile due to chemotherapy or radiation, and since their sperm or eggs have not matured, assisted reproduction using those sperm or eggs is not an option when they become adults. Now in a major first, researchers at the University of […]

Researchers at Karolinska Institutet have found that type IgG antibodies play an unexpected role in atherosclerosis. A study on mice shows that the antibodies stabilise the plaque that accumulates on the artery walls, which reduces the risk of it rupturing and causing a blood clot. It is hoped that the results, […]

Enlarged perivascular spaces, which are commonly seen on brain MRIs in older adults, have important associations with worse cognitive performance, particularly information processing speed and executive function, according to a new study that challenges historical consideration that perivascular spaces are a harmless imaging marker. Enlarged perivascular spaces are fluid-filled spaces […]

A single allergic reaction during pregnancy prompts sexual-development changes in the brains of offspring that last a lifetime, new research suggests. Female rats born to mothers exposed to an allergen during pregnancy acted more characteristically “male” – mounting other female rodents, for instance – and had brains and nervous systems […]

Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis. Kinases are a large group of hundreds of […]

Eisai Co., Ltd. announced that a global Phase III clinical study (Clarity AD/Study 301) of BAN2401, an anti-amyloid beta protofibril antibody, in patients with early Alzheimer's disease has been initiated. BAN2401 is being jointly developed by Eisai and Biogen Inc. Clarity AD is a global placebo-controlled, double-blind, parallel-group, randomized study […]

Professor Otger Campàs receives 2019 Elizabeth D. Hay New Investigator Award from the Society for Developmental Biology. How do we develop from a mass of undifferentiated cells into organisms of tissues and organs with specific three-dimensional morphologies and architectures? That question has been one of the perennial mysteries at the […]