February 20, 2018

Blocking action of gene enhancers halts spread of tumor cells

In one of the first successes of its kind, researchers from Case Western Reserve University School of Medicine and six other institutions have inhibited the spreading of cancer cells from one part of the body to another. In doing so, they relied on a new model of how cancer metastasizes […]
February 20, 2018

Not being aware of memory problems predicts onset of Alzheimer’s disease

Doctors who work with individuals at risk of developing dementia have long suspected that patients who do not realize they experience memory problems are at greater risk of seeing their condition worsen in a short time frame, a suspicion that now has been confirmed by a team of McGill University […]
February 20, 2018

Successful NK cell-based immunotherapy for leukaemia

NK (natural killer) cells are a special type of white blood cell discovered at Karolinska Institutet in the 1970s that can recognise and kill cancer cells. In recent years, much knowledge has been generated on the biology of the cells and their ability to recognise tumour cells. Research into immunotherapy, […]
February 20, 2018

Possible new principle for cancer therapy

Humans need the chemical element selenium for good health. The selenium-containing enzyme thioredoxin reductase 1 (TrxR1) can be used to support the growth of various cells and to protect them from harmful forms of oxygen radicals, known as oxidative stress. Selenium intake has long been a topic of discussion in […]
February 20, 2018

Atlas of brain blood vessels provides fresh clues to brain diseases

The vasculature of the brain is, like elsewhere on the body, made up of arteries, veins and thin, intervening vessels called capillaries through which the main exchange of oxygen, nutrients and waste products takes place. However, the vessels of the brain differ from others in one important respect – the […]
February 20, 2018

Calcium may play a role in the development of Parkinson’s disease

Researchers have found that excess levels of calcium in brain cells may lead to the formation of toxic clusters that are the hallmark of Parkinson’s disease. The international team, led by the University of Cambridge, found that calcium can mediate the interaction between small membranous structures inside nerve endings, which […]
February 20, 2018

Sleep problems in menopause linked to hot flashes, depression – and may not last

Sleep disruptions are one of the most commonly reported complaints among menopausal women. A new study of middle-aged women found that sleep problems vary across the stages of menopause, yet are consistently correlated with hot flashes and depression. The findings suggest that addressing those risk factors may also address sleep disruptions, as […]
February 20, 2018

Fifteen new genes identified that shape our face

Researchers from KU Leuven, Belgium, and the universities of Pittsburgh, Stanford and Penn State have identified 15 genes that determine our facial features. The findings were published in Nature Genetics. Our DNA determines what we look like, including our facial features. That appeals to the popular imagination, as the potential […]
February 19, 2018

NIH releases first dataset from unprecedented study of adolescent brain development

The National Institutes of Health Tuesday released to the scientific community an unparalleled dataset from the Adolescent Brain Cognitive Development (ABCD) study. To date, more than 7,500 youth and their families have been recruited for the study, well over half the participant goal.  Approximately 30 terabytes of data (about three […]
February 19, 2018

Slow it Down

For most prostate cancer patients, androgen-deprivation therapy, either through surgical removal of the testicles or the use of drugs that suppress testosterone production, is the standard treatment. Unfortunately, androgen deprivation stops working for almost all patients, leading to what is called castration-resistant disease. In such patients whose cancer has not […]
February 15, 2018

Nitrate in drinking water increases the risk of colorectal cancer

Nitrate in groundwater and drinking water, which primarily comes from fertilisers used in the agricultural production, has not only been subject to decades of environmental awareness – it has also been suspected of increasing the risk of cancer. The largest epidemiological study ever carried out in this area now shows that […]
February 15, 2018

Motion Capture-like Technology for Tracking Protein Shape

In many modern animated movies, the trick to achieving realistic movements for individual characters and objects lies in motion-capture technology. This process often involves someone wearing a tracking suit covered in small, colored balls while a camera captures the position of those colored balls, which is then used to represent […]
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