July 10, 2019

New method helping to find deletions and duplications in the human genome

A new machine-learning method accurately identifies regions of the human genome that have been duplicated or deleted — known as copy number variants — that are often associated with autism and other neurodevelopmental disorders. The new method, developed by researchers at Penn State, integrates data from several algorithms that attempt […]
July 10, 2019

Light therapy could replace opioids as main treatment for cancer treatment side effect

A worldwide coalition of researchers and clinicians has agreed that light therapy is among the most effective interventions for the prevention of oral mucositis, painful ulcers in the mouth resulting from cancer therapy. The new guidelines from the Multinational Association of Supportive Care in Cancer (MASCC) and International Society of […]
July 10, 2019

Genetic Origin of Severe Developmental Eye Condition Identified

The finding is a promising step forward in understanding eye growth – and potentially fixing near- and far-sightedness. Those with a rare genetic condition called nanophthalmos have abnormally small eyes whose internal structures – including the size of the lens – are otherwise normal. The condition can cause a host […]
July 10, 2019

Hinge-like protein may open new doors in cystic fibrosis treatment

In recent decades, treatment options for people with cystic fibrosis have improved dramatically. The newest drugs, known as potentiators, target a protein called cystic fibrosis transmembrane conductance regulator, which is mutated in people with the disease. Yet, while these medications can help some people with cystic fibrosis, they are far […]
July 10, 2019

Molecules that Restructure the Mind

Imagine a molecule powerful enough to reconfigure your mind and body — a molecule that makes your bones and muscles grow, makes your organs behave differently and alters your mind and your mood. Such is the power of sex hormones — estrogen, progesterone and testosterone. These naturally occurring chemicals are […]
July 10, 2019

It's not an antibody, it's a frankenbody: A new tool for live-cell imaging

Scientists at Colorado State University (CSU) and Tokyo Institute of Technology (Tokyo Tech) have developed a new powerful tool called a “frankenbody”, for imaging protein dynamics in living cells. Just as Frankenstein's monster is stitched together from different limbs, the frankenbody was created by taking the binding regions of a […]
July 9, 2019

Anti-worm drug inhibits tumour growth and spread in mice

Researchers at UNSW Sydney have discovered that a drug used for almost 40 years to treat worm infections in humans and animals can be used to inhibit melanoma growth and spread in mice. The drug, which is available over-the-counter in Europe, is a so-called anthelmintic used to control parasitic infections. […]
July 9, 2019

Researchers probe cell division defects to gain insight into cancer

From bugs to plants to animals, for all living things to grow they must create more cells. To do so, each existing cell, whether in an embryo or an adult, receives cues to copy its chromosomes — large pieces of DNA that contain each cell’s entire genetic code. In a […]
July 9, 2019

Major breakthrough in the treatment of leukemia

A molecular process involved in the action of anti-leukemia drugs has been discovered at Université de Montréal’s Institute for Research in Immunology and Cancer (IRIC). While calling into question a central tenet of oncology, this discovery, published in the journal Cancer Cell, also holds promise for the development of effective treatments in the […]
July 9, 2019

Researchers can finally modify plant mitochondrial DNA

Researchers in Japan have edited plant mitochondrial DNA for the first time, which could lead to a more secure food supply. Nuclear DNA was first edited in the early 1970s, chloroplast DNA was first edited in 1988, and animal mitochondrial DNA was edited in 2008. However, no tool previously successfully […]
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