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Interfering with the motion of a kinase enzyme might be a new approach for the development of anti-cancer drugs, new UA-led research suggests. Revealing all the steps required to activate an enzyme called a protein kinase may identify new ways to target cancer, according to new University of Arizona-led research. […]

Jean-François Côté, a researcher at the Montreal Clinical Research Institute (IRCM) and professor at Université de Montréal’s Faculty of Medicine, studies metastasis, the leading cause of cancer-related death. Recently, his team uncovered a protein that, once deactivated, could prevent the development of metastases in an aggressive type of cancer, HER2-positive […]

In a 10-patient cohort study led by Dr. Jean Roy, hematologist and professor at the Faculty of Medicine of Université de Montréal, that aims to understand how to mitigate the risks associated with the treatment of multiple myeloma, a malignant cancer, researchers have adopted an innovative approach based on the unique immunological […]

Dementia should join the expanding list of possible complications following concussion, even if the patient did not lose consciousness, say researchers from UCSF Weill Institute for Neurosciences and the San Francisco Veterans Affairs Health Care System. In their study, which tracked more than one-third of a million veterans, the likelihood of dementia was […]

The big question As an embryo develops from a little glob of primitive cells, it patterns itself into precise, spatially organized regions and tissues. This requires that individual cells coordinate with one another over long distances by releasing and detecting specialized signaling molecules. How can cells, communicating only in this […]

Mutations in genes that help repair damage to DNA may aid in predicting the prognosis of patients with bladder and other related cancers, according to researchers. The researchers found that bladder cancer patients who had mutations in their ATM or RB1 genes — proteins that help repair DNA damage when […]

Device could help advance regenerative medicine A UCLA bioengineer has developed a technique that uses a specially adapted 3D printer to build therapeutic biomaterials from multiple materials. The advance could be a step toward on-demand printing of complex artificial tissues for use in transplants and other surgeries. “Tissues are wonderfully […]

For years, researchers have known that a gene called EAK-7 plays an important role in determining how long worms will live. But it remained unclear whether the gene had a counterpart in humans and – if it did – how that human version would work. Now, researchers led by UCLA’s […]

A new study identifies a molecule that may be critical to the repair of white matter, the fatty tissue wrapped around parts of brain cells that helps speed up communication. Damage to white matter is associated with several conditions, including multiple sclerosis and cerebral palsy, and can occur in the […]

Men who take once-daily aspirin have nearly double the risk of melanoma compared to men who are not exposed to daily aspirin, reports a new Northwestern Medicine study. Women, however, do not have an increased risk in this large patient population. “Given the widespread use of aspirin and the potential […]

Personalized therapies are the future, but they do pose a challenge. If every therapy will be different, how do you test them? Obviously, doctors would have the best test subject available – the patient, but you can only do so much with him. Now a team if scientists lead by […]

A team of medical researchers have taken a step in investigating whether a type of RNA found to be linked to cancers — called microRNAs — could one day be used as a more accurate screening test for prostate cancer. The researchers said that out of the 733 microRNAs analyzed […]