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A 49-year-old man notices a painless rash on his shoulder but doesn’t seek care. Months later, during a routine physical, his doctor notices the rash and diagnoses it as a benign skin condition. More time passes, and during a routine screening test, a nurse points out the rash to another […]

Colorectal cancer is the second deadliest cancer in the United States, and just six out of 10 adults in the age range recommended for routine screening—50 to 75—reported having it done in 2015. When patients do not keep up with screening, the risk of death is substantially higher, so Penn […]

Researchers have developed a computational model for human MEK1, a protein with potential as a drug target for a variety of human cancers. The initiation and progression of cancer cells occur when molecular signals involved in cellular proliferation go awry. MEK1 plays an essential role in signaling within both healthy […]

New immunotherapies can dramatically defeat cancer. But more often, cancer evades them, and doctors need to know quickly when that happens, so they can adjust treatment. An experimental urine test to detect immunotherapy effectiveness very early has received a major funding boost. The National Institutes of Health has granted $1.8 […]

It's possible to prod immune cells to attack and kill pancreatic cancer cells, according to a report from scientists at the University of Washington School of Medicine and the Fred Hutchinson Cancer Research Center in Seattle.  Their findings challenge the commonly held view that pancreatic cancer does not elicit an immune system response that […]

A group of University of Georgia researchers led by geneticist Douglas Menke has become the first in the world to successfully produce a genetically modified reptile—specifically, four albino lizards—using the CRISPR-Cas9 gene-editing tool. The team’s results, which appeared online, have been submitted for peer review. “Reptiles are very understudied in terms […]

New research from the University of Pittsburgh School of Medicine and the UPMC Hillman Cancer Center sheds light on how tumors use the body’s regulators of immunity for their own benefit. Published in Nature Immunology, the findings could be used to develop the next generation of immune therapies to fight various cancers. “While cancer immunotherapy […]

Seven types of bacteria and certain immune factors in a woman’s vagina and cervix may be responsible for increasing the risk of spontaneous preterm birth (sPTB) or protect against it, according to a new study from the Perelman School of Medicine at the University of Pennsylvania and the University of […]

Prostate cancer can grow slowly and pose little threat to patients, or it can metastasize quickly, causing severe pain and death. But as of now, it’s nearly impossible to determine which type of cancer a patient has during the early stages. Now, University at Buffalo researchers and scientists from Moscow […]

Devising the best treatment for a patient with cancer requires doctors to know something about the traits of the cancer from which the patient is suffering. But one of the greatest difficulties in treating cancer is that cancer cells are not all the same. Even within the same tumor, cancer […]

A prototype wearable device, tested in animal models, can continuously collect live cancer cells directly from a patient’s blood. Developed by a team of engineers and doctors at the University of Michigan, it could help doctors diagnose and treat cancer more effectively. “Nobody wants to have a biopsy. If we […]

A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered. The investigators found that in addition to its known ability to block the production of cell growth […]