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Many chemotherapy drugs kill cancer cells by severely damaging their DNA. However, some tumors can withstand this damage by relying on a DNA repair pathway that not only allows them to survive, but also introduces mutations that helps cells become resistant to future treatment. Researchers at MIT and Duke University […]

The pecan is a North American deciduous walnut tree. Its seeds, pecan nuts, are sweeter in flavor than walnuts and are said to be more popular than almonds in the U.S. What deserves attention is the pecan nut’s antioxidant power. It’s said to have more anti-aging effect than the walnut, […]

A two-week course of an experimental immunotherapy called teplizumab dramatically reduced type 1 diabetes (T1D) diagnosis rates in people at high risk for the disease, according to newly published phase II clinical trial results. This is the first time a drug has been able to delay or prevent the disease, […]

Treatments for both adults and children need to change to avoid a type 2 diabetes epidemic, researchers say. Intervening aggressively to roll back the onset of type 2 diabetes does works in adults, but once the medication and treatment ends, the disease always returns, according to a study published in the journal Diabetes […]

Doctors could soon get some help from an artificial intelligence tool when diagnosing brain aneurysms – bulges in blood vessels in the brain that can leak or burst open, potentially leading to stroke, brain damage or death. The AI tool, developed by researchers at Stanford University and detailed in a […]

Taking a daily vitamin D supplement does not prevent type 2 diabetes in adults at high risk, according to results from a study funded by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health.  The Vitamin D and Type 2 Diabetes (D2d) study enrolled 2,423 adults […]

BRCA—the family of DNA-repair proteins associated with breast, ovarian prostate, and pancreatic cancers—interacts with a multipart, molecular complex that is also responsible for regulating the immune system. When certain players in this pathway go awry, autoimmune disorders, like lupus, can arise. Now, researchers in the Perelman School of Medicineat the University […]

Researchers encourage more conversation, better documentation of wishes. Careful documentation of a hospice patient’s end-of-life wishes – and prominently noting that information in health records early – could prevent unwanted hospitalizations and medical interventions, a new study suggests. Researchers at The Ohio State University analyzed the health records of 1,185 […]

Cells prepare for different developmental paths and make multiple choices on their way to their final state, a study by researchers at Karolinska Institutet, Harvard Medical School and elsewhere published in Science shows. The findings can help pinpoint where cells may “take the wrong turn” and become malignant. The human […]

PNNL scientist sifts for clues from more than 1,000 human brains A substance known as amyloid beta protein gets a lot of attention from scientists. Beta amyloid, as it’s also called, is a normal brain protein found in everyone, but for unknown reason it gunks up in the brains of […]

According to the Mayo Clinic, about 20% of breast cancers make abnormally high levels of a protein called human epidermal growth factor receptor 2 (HER2). When displayed on the surface of cancer cells, this signaling protein helps them proliferate uncontrollably and is linked with a poor prognosis. Now, researchers have […]

From the light-sensing cones of the retina to the blood-pumping muscle of the heart to the waste-filtering units of the kidneys, the human body is made up of hundreds of cell types exquisitely specialized to perform their jobs with great precision. This complexity, however, belies the fact that each of […]