April 12, 2019

Turning patients’ own cells into cancer fighters

The next cancer therapy could be a patient’s own cells. Tactiva Therapeutics, a Buffalo-based immuno-oncology startup, is developing a personalized cancer treatment based on engineered immune cells derived from patients’ own cells. The company’s approach involves attaching proteins called receptors to these cells. The receptors target antigens present in cancer […]
April 12, 2019

Personalized medicine for children with cancer

This may help identify the cause of the cancer, so that the children can receive more precise treatment in the long term and avoid unnecessary side effects. Personalized medicine is now a reality for Danish children with cancer. If children can be prevented from dying from the disease, receive a […]
April 12, 2019

Blood-based screen for colon cancer shows promise

If caught early, nearly all cases of colon cancer are curable. Though this should make screening tests straightforward, colon cancer screening suffers from a paradoxical combination of low compliance rates and overdiagnosis. In a study published in the Proceedings of the National Academy of Sciences, University of Wisconsin–Madison scientists identified four blood-based fingerprints – […]
April 12, 2019

NASA’s Landmark Twins Study Reveals Resilience of Human Body in Space

Results from NASA’s landmark Twins Study, which took place from 2015-2016, were published Thursday in Science. The integrated paper — encompassing work from 10 research teams — reveals some interesting, surprising and reassuring data about how one human body adapted to — and recovered from — the extreme environment of space. The Twins Study provides the […]
April 12, 2019

In cellular world, strong relationships the key to healing old wounds

Yale scientists with colleagues at University College London have taken the next step towards unravelling how cells work together during wound closure, a question that could be fundamental to determining optimal healing rates after injury or disease. How cells behave, the rate at which they repair skin tissue, and how […]
April 11, 2019

A New Role for Genetics in Cancer Therapy-Induced Cardiomyopathy

Recent advances in the development of cancer therapies have increased long-term survival and prognosis. However, the increased burden and prevalence of harmful side effects, including cardiomyopathy, have emerged alongside those therapeutic benefits. In particular, there have been increases in cancer therapy-induced cardiomyopathy (CCM) — a heart condition which may compromise […]
April 11, 2019

New tool helps find genetic culprits in cancer’s spread

The ability of cancer to establish itself in distant parts of the body — called metastasis — causes 90% of deaths from solid tumors. Metastasis is the result of complex genetic interactions that have proven difficult for scientists to study. Now Yale researchers have devised a way to identify some […]
April 11, 2019

Screening also prevents rare types of cervical cancer

Rare types of cervical cancer can be effectively prevented with screening, a comprehensive study of identified cases of rare cervical cancer over a ten-year period in Sweden concludes. The study was conducted by researchers at Karolinska Institutet and is published in The BMJ. The main aim of cervical screening is to […]
April 11, 2019

Long-lived Bats Appear to Hold Secrets of Mammal Longevity

University of Maryland researchers analyzed a DNA-based evolutionary tree for a majority of known bat species and found four bat lineages that exhibit extreme longevity. They also identified for the first time two traits that predict extended life spans in bats. Their work is described in a research paper, published […]
April 11, 2019

New quantum material could warn of neurological disease

By speaking the brain’s language, the material is a portal between electronics and the brain. WEST LAFAYETTE, Ind. — What if the brain could detect its own disease? Researchers have been trying to create a material that “thinks” like the brain does, which would be more sensitive to early signs […]
April 10, 2019

Tidying up: A new way to direct trash to autophagy

Researchers find new way to clean up cells; discovery could aid attack on human disease. Marie Kondo herself couldn’t do it any better. Usually cells are good at recognizing what doesn’t spark joy. They’re constantly cleaning house — picking through their own stuff to clear out what no longer works. […]
April 10, 2019

New hope for treating childhood brain cancer

There could be new treatments on the horizon for diffuse intrinsic pontine glioma, or DIPG, a devastating form of brain cancer that afflicts young children and is currently incurable. Recent experiments in animal models of the disease have identified an experimental drug that effectively destroys DIPG cells. And a team […]
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