November 23, 2020

A DNA-based nanogel for targeted chemotherapy

Current chemotherapy regimens slow cancer progression and save lives, but these powerful drugs affect both healthy and cancerous cells. Now, researchers reporting in ACS’ Nano Letters have designed DNA-based nanogels that only break down and release their chemotherapeutic contents within cancer cells, minimizing the impacts on normal ones and potentially eliminating painful […]
November 23, 2020

Frozen eggs and ovarian tissue helped women conceive children after breast cancer

Women with breast cancer whose eggs or ovarian tissue were frozen had more children after their diagnosis than women who did not undergo fertility preservation using those methods before the start of cancer treatment. That is according to a study by researchers at Karolinska Institutet in Sweden, published in JAMA […]
November 22, 2020

New NIH BRAIN Initiative awards move toward solving brain disorders

The National Institutes of Health will fund more than 175 grants, totalling nearly $500 million, through the NIH’s Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, part of a large effort among federal and non-federal partners to use knowledge about how the brain works to develop more effective therapies for […]
November 21, 2020

A gene mutation that protects against disease

Researchers at the Montreal Clinical Research Institute, Université de Montréal and McMaster University think they’ve found a fountain of youth — and it’s unique to a few French Canadian families. Canadian scientists looking at a rare genetic mutation think they may have discovered the proverbial fountain of youth. But it’s […]
November 21, 2020

Research boost to find treatments for 'undruggable' cancers

A research team at the University of Bath, in collaboration with biotechnology company Sapience Therapeutics, is redoubling its efforts to discover new peptide-based treatments capable of acting upon 'undruggable' targets in cancer cells. Some cancers are notoriously resistant to treatment – it is these tumours that are the focus of the […]
November 21, 2020

Minuscule Migrations

Cells move constantly throughout our bodies, performing myriad operations critical to tissue development, immune responses and general wellbeing. This bustle is guided by chemical cues long studied by scientists interested in cellular migration. To better understand this phenomenon, a team of biologists and physicists, led by UC Santa Barbara’s Distinguished […]
November 21, 2020

What Platelets and Endothelial Cells May Reveal About the Coronavirus Disease

Yale researchers have helped identify the mechanisms behind a major cause of morbidity and mortality in COVID-19 patients. Extensive blood clots in both large and small blood vessels in the lungs and throughout many major organs in the body have been linked to worse outcomes in patients hospitalized with severe […]
November 20, 2020

Neurons stripped of their identity are hallmark of Alzheimer's disease, study finds

Researchers at the University of California San Diego have identified new Alzheimer's disease mechanisms in neurons. The scientists have discovered that changes in the structure of chromatin, a tightly coiled form of DNA, trigger neurons to lose their specialized function and revert to an earlier cell state. That results in the loss […]
November 20, 2020

Vitamin D Supplements May Reduce Risk of Developing Advanced Cancer

For many years, investigators have been trying to pin down the tantalizing connection between vitamin D and cancer. Epidemiological studies have found that people who live near the equator, where exposure to sunlight produces more vitamin D, have lower incidence and death rates from certain cancers. In cancer cells in […]
November 20, 2020

Cancer Crosstalk

Any given tumor is composed of a multitude of cell types that can each look or behave differently from its neighbors. An emerging body of research suggests that these differences can influence disease progression or the way a tumor responds to drugs. Now, a new study by Harvard Medical School […]
November 20, 2020

Revolutionary CRISPR-based genome editing system treatment destroys cancer cells

Researchers at Tel Aviv University (TAU) have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer. The researchers developed a novel lipid nanoparticle-based delivery system that specifically targets cancer cells and destroys them by genetic manipulation. The […]
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