Related Science News – Page 108 – Innovita Research

Related Science News

January 29, 2021

Advocating the Use of Low Dose Ionizing Radiation as a Hormetic Treatment

Many forms of mild cellular stress produce benefits to health because they trigger the more efficient operation of cellular maintenance processes such as autophagy. That in turn causes better cell and tissue function, and thus improved health. This stress response and benefit is known as hormesis, and has been robustly […]
January 29, 2021

Researchers use patients’ cells to test gene therapy for rare eye disease

Scientists at the National Eye Institute (NEI) have developed a promising gene therapy strategy for a rare disease that causes severe vision loss in childhood. A form of Leber congenital amaurosis, the disease is caused by autosomal-dominant mutations in the CRX gene, which are challenging to treat with gene therapy.  The scientists […]
January 29, 2021

Nixing bone cancer fuel supply offers new treatment approach, mouse study suggests

An innovative approach to treating bone tumors — starving cancer cells of the energy they need to grow — could one day provide an alternative to a commonly used chemotherapy drug without the risk of severe side effects, suggests a new study from Washington University School of Medicine in St. […]
January 29, 2021

Researchers Identify Nanoparticles that Could Be Used in Therapeutic mRNA Delivery before Birth

Researchers at Children’s Hospital of Philadelphia and the School of Engineering and Applied Science at the University of Pennsylvania have identified ionizable lipid nanoparticles that could be used to deliver mRNA as part of fetal therapy. The proof-of-concept study, published in Science Advances, engineered and screened a number of lipid nanoparticle […]
January 29, 2021

How does the immune system keep tabs on the brain?

Alzheimer’s disease, multiple sclerosis, autism, schizophrenia and many other neurological and psychiatric conditions have been linked to inflammation in the brain. There’s growing evidence that immune cells and molecules play a key role in normal brain development and function as well. But at the core of the burgeoning field of […]
January 29, 2021

Parkinson’s disease risk and severity is tied to the activity of a channel in cells’ ‘recycling centers’

Many genetic mutations have been found to be associated with a person’s risk of developing Parkinson’s disease. Yet for most of these variants, the mechanism through which they act remains unclear. Now a new study in Nature led by a team from the University of Pennsylvania has revealed how two different variations—one […]
January 29, 2021

New TAU study reveals “Achilles’ heel” of cancer cells

What makes cancer cells different from ordinary cells in our bodies? Can these differences be used to strike at them and paralyze their activity? Cancer researchers have been debating this question since the mid-19th century. A new study from Tel Aviv University (TAU) shows, for the first time, how an abnormal […]
January 29, 2021

First ever ‘pioneer’ factor found in plants enables cells to change their fate

Cells don’t express all the genes they contain all the time. The portion of our genome that encodes eye colour, for example, doesn’t need to be turned on in liver cells. In plants, genes encoding the structure of a flower can be turned off in cells that will form a […]
January 29, 2021

Study: Detecting ADHD with near perfect accuracy

A new study led by a University at Buffalo researcher has identified how specific communication among different brain regions, known as brain connectivity, can serve as a biomarker for attention deficit hyperactivity disorder (ADHD). The research relied on a deep architecture using machine-learning classifiers to identify with 99% accuracy those […]
January 29, 2021

Alcohol Causes Immediate Effects Linked to Heart Malady

A daily alcoholic drink for women or two for men might be good for heart health, compared to drinking more or not drinking at all. But while there is some evidence that drinking in moderation might prevent heart attacks, now a randomized, double-blinded clinical study of 100 heart patients has […]
January 29, 2021

Abnormal hyperactivation in the brain may be an early sign of Alzheimer’s

Abnormally hyperactive areas in the brain may help better predict the onset of Alzheimer’s disease, according to findings of a research team led by Université de Montreal researcher Sylvie Belleville, Scientific Director of the Institut Universitaire de gériatrie de Montréal research centre and professor in the Department of Psychology at […]
January 29, 2021

Genetic analysis of symptoms yields new insights into PTSD

Attempts to identify the genetic causes of neuropsychiatric diseases such as post-traumatic stress disorder (PTSD) through large-scale genome-wide analyses have yielded thousands of potential links. The challenge is further complicated by the wide range of symptoms exhibited by those who have PTSD. For instance, does extreme arousal, anger, or irritation […]
January 28, 2021

When — Not What — Obese Mice Ate Reduced Breast Cancer Risk

Restricting eating to an eight-hour window, when activity is highest, decreased the risk of development, growth and metastasis of breast cancer in mouse models, report researchers at University of California San Diego School of Medicine, Moores Cancer Center and Veterans Affairs San Diego Healthcare System (VASDSH). The findings, published in […]
January 28, 2021

Two Anti-viral Enzymes Transform Pre-Leukemia Stem Cells into Leukemia

Cancers, such as leukemia and multiple myeloma. The self-renewing nature of cancer stem cells makes them particularly hard to eradicate, and they’re often the reason a blood cancer reoccurs. Researchers at UC San Diego Health and University of California San Diego School of Medicine are working to understand what pushes […]
January 28, 2021

Keeping sperm cells on track

One essential component of each eukaryotic cell is the cytoskeleton. Microtubules, tiny tubes consisting of a protein called tubulin, are part of this skeleton of cells. Cilia and flagella, which are antenna-like structures that protrude from most of the cells in our body, contain many microtubules. An example of flagell […]
January 28, 2021

The Enormous Clinical Potential of Senotherapeutics for the Treatment of Chronic Kidney Disease

Today's open access review paper is a high level look at what the newfound realization of the importance of senescent cells to aging and age-related disease means for the treatment of chronic kidney disease. At present there are few good options for treatment, and those therapies that are widely used […]
January 28, 2021

On nights before a full moon, people go to bed later and sleep less, study shows

For centuries, humans have blamed the moon for our moods, accidents and even natural disasters. But new research indicates that our planet’s celestial companion impacts something else entirely — our sleep. In a paper published in Science Advances, scientists at the University of Washington, the National University of Quilmes in Argentina […]
January 28, 2021

A protein that can melt tumors discovered at Vanderbilt

For the second time, cancer researchers at Vanderbilt have discovered a protein that—when genetically manipulated to impede it from interacting with a gene responsible for cancer genesis—effectively melts tumours in days.  The article, “MYC regulates ribosome biogenesis and mitochondrial gene expression programs through interaction with Host Cell Factor-1,” was published in the […]
January 28, 2021

Cell death shines a light on the origins of complex life

Organelles continue to thrive after the cells within which they exist die, a team of University of Bristol scientists have found, overturning previous assumptions that organelles decay too quickly to be fossilised. As described in the journal Sciences Advances, researchers from Bristol’s School of Earth Sciences were able to document the […]
January 28, 2021

Sustainable optical fibres developed from methylcellulose

The state-of-the-art silica glass optical fibres can carry light signals over tens of kilometres with very low optical loss and provide high-capacity communication networks. However, their brittleness, low stretchability and energy intensiveness make them less suitable for local short-range applications and devices such as automotive, digital home appliances, fabrics, laser […]
January 28, 2021

How a Cancer Drug Carrier's Structure Can Help Selectively Target Cancer Cells

Porphyrins are interesting drug delivery vehicles that can specifically accumulate in cancer cells. However, how the structure of the drug-conjugated porphyrin affects its ability to penetrate and accumulate within cancer cells is not well understood. Researchers from the Tokyo University of Science now investigate the correlation between the structure and […]
January 28, 2021

Robust AI tools to predict future cancer

To catch cancer earlier, we need to predict who is going to get it in the future. The complex nature of forecasting risk has been bolstered by artificial intelligence (AI) tools, but the adoption of AI in medicine has been limited by poor performance on new patient populations and neglect to racial minorities. […]
January 28, 2021

Human Protein Atlas – Single Cell Classification: Challenge

There are billions of humans on this earth, and each of us is made up of trillions of cells. Just like every individual is unique, even genetically identical twins, scientists observe differences between the genetically identical cells in our bodies. Differences in the location of proteins can give rise to […]
January 28, 2021

Machine Learning Algorithm Predicts Risk of Antibody-Related Autism with 100% Accuracy Based on Mother’s Plasma

Thanks to modern artificial intelligence technology, researchers at the UC Davis MIND Institute have recently succeeded in accurately predicting the risk of Autism Spectrum Disorder (ASD) on the basis of specific patterns of maternal auto-antibodies, i.e., antibodies that attack the tissues of their own hosts. “The implications from this study […]
January 27, 2021

The New Gold Standard: Anti-cancer Drug Discovery Made Easier with Gold Nanostructures

Scientists design a novel 3D cell culture-based electrical platform for high-throughput anti-cancer drug testing using a new type of gold nanostructure. Brain cancer is one of the deadliest forms of cancer with poor treatability. Now, scientists from Korea and China have developed a multi-functional platform using gold nanostructures that allows […]
January 27, 2021

A Review of Research into Intermittent Fasting and its Effects on Longevity

Intermittent fasting (such as alternate day fasting) is not as effective as calorie restriction (consistent reduction in calories every day) in extending life span in animal models such as mice, but it does have many of the same effects on health and longevity. Even when total calorie intake is held […]
January 27, 2021

Epigenetic mechanisms that regulate macrophage inflammation discovered

How do cis-regulatory genome elements regulate gene expression, what are the critical components involved, and can we therapeutically target them? By investigating how corepressors modulate enhancers and silencers during inflammatory macrophage activation, BioNut researchers have found some unexpected answers to these fundamental questions. The study is published in Molecular Cell. […]
January 27, 2021

Surprising Behavior of Transcription Factors Challenges Theories of Gene Regulation

How cells develop and the diseases that arise when development goes wrong have been a decades-long research focus in the laboratory of Distinguished Professor of Biology Ellen Rothenberg. In particular, the lab studies the development of immune cells known as T cells, which act as “intelligence agents”—they circulate throughout the body, […]
January 27, 2021

What is Personality?

An individual's personality does not lie in their behavior or their genes but in the brain, according to a new theoretical study. Do you value courage and bravery or intelligence and learning? Your answer may indicate whether you end up in Gryffindor or Ravenclaw, according to a Harry Potter-themed personality […]
January 27, 2021

Machine learning tool used to predict early symptoms of schizophrenia in relatives of patients

University of Alberta researchers have taken another step forward in developing an artificial intelligence tool to predict schizophrenia by analyzing brain scans. In recently published research, the tool was used to analyze functional magnetic resonance images of 57 healthy first-degree relatives (siblings or children) of schizophrenia patients. It accurately identified the […]