Related Science News – Page 3 – Innovita Research

Related Science News

November 7, 2019

One Fell Swoop

As we age, our bodies tend to develop diseases such as heart failure, kidney failure and diabetes, and the presence of anyone disease increases the risk of developing others. A drug usually targets only one condition, largely ignoring the interconnectedness of age-related diseases and requiring patients to take multiple drugs, […]
November 7, 2019

New assessment could identify risks of frailty

Signs of frailty and the risks it brings could be identified in young and old people alike through a new assessment developed in a study by researchers at the Universities of Strathclyde, Manchester, Liverpool, Edinburgh, and Yale. Increasing the risk of frailty is a defining characteristic of the aging process […]
November 7, 2019

A Game-Changing Test for Prion, Alzheimer's, and Parkinson's Diseases is on the Horizon

Synthetic molecules made at Berkeley Lab can be used to diagnose numerous devastating illnesses. There are currently no effective treatments for prion diseases, a family of fatal neurodegenerative conditions caused by accumulations of misfolded copies of a naturally occurring protein. But now, there is finally an effective way to test […]
November 6, 2019

Mechanism of beta-cells involved in the development of type-1 diabetes revealed

Researchers Lorenzo Pasquali and Mireia Ramos-Rodríguez have published recently in Nature Genetics the results of a study on the mechanisms that cause an inflammatory response to trigger pancreatic beta-cell death, leading to the onset of Type 1 Diabetes (T1D). L. Pasquali is a Ramon y Cajal researcher at the Josep […]
November 6, 2019

Researchers identify certain gut bacteria that may be involved in causing bowel cancer

People who have a certain type of bacteria in their guts may be at greater risk of developing bowel cancer. The findings will be presented by the University of Bristol researcher, Dr. Kaitlin Wade, at the 2019 NCRI Cancer Conference in Glasgow. While there is increasing evidence that the make-up […]
November 6, 2019

New technology delivers genome editing complexes directly to stem cells

The development of a set of strategies for delivering genome editing complexes directly to stem cells has earned a group of innovators at Case Western Reserve University School of Medicine a first-year grant of nearly $700,000 through the National Institutes of Health (NIH) Somatic Cell Genome Editing Program. The work […]
November 6, 2019

Scrambled cytoplasm from frog eggs organizes into cell-like structures

Can scrambled eggs unscramble themselves? Well, sort of. The cytoplasm of ruptured Xenopus frog eggs spontaneously reorganizes into cell-like compartments, according to a study by researchers at the Stanford University School of Medicine. “We were gobsmacked,” said James Ferrell, MD, Ph.D., professor of chemical and systems biology and of biochemistry. “If you blend a […]
November 6, 2019

Unique case of disease resistance reveals possible Alzheimer’s treatment

Defying the odds, an individual at high risk for early-onset Alzheimer’s disease remained dementia-free for many years beyond what was anticipated. A study funded in part by the National Institute on Aging (NIA), part of the National Institutes of Health, led researchers to suggest that a gene variant may be […]
November 6, 2019

Cell signalling breakthrough opens up new avenues for research

Researchers at the University of Liverpool have made a major breakthrough in the field of cell signaling. In humans, signaling in cells normally regulates cell growth and repair. However, abnormal cell signaling contributes to many diseases, including cancer and neurodegeneration. Therefore, identifying specific proteins that control cell signaling in health […]
November 5, 2019

Scientists identify protein that promotes brain metastasis

A protein that breast, lung and other cancers use to promote their spread – or metastasis – to the brain, has been identified by a team led by Weill Cornell Medicine and NewYork-Presbyterian investigators. The protein, CEMIP, will now be a focus of efforts to predict, prevent and treat brain […]
November 5, 2019

Nanoparticle orientation offers a way to enhance drug delivery

MIT engineers have shown that they can enhance the performance of drug-delivery nanoparticles by controlling a trait of chemical structures known as chirality — the “handedness” of the structure. Many biological molecules can come in either right-handed or left-handed forms, which are identical in composition but are mirror images of […]
November 5, 2019

New process of the antitumor response of NK cells in myeloma discovered

NK cells mean Natural Killer cells. They are part of the innate immune system. They are known primarily for their ability to recognize and kill tumor cells, cells infected by viruses and bacteria, or dying by apoptosis. Although evidence about their antitumoral capacity, how this activity occurred remained unknown. The […]
November 5, 2019

Blood Test Can Predict Prognosis in Deadly Brain Cancer

A blood test that measures the amount of cell-free DNA (cfDNA) in the bloodstream – called a liquid biopsy – correlates with how patients will progress after they are diagnosed with glioblastoma (GBM), the deadliest and most common primary brain tumor in adults. In a new study, researchers from the Abramson […]
November 5, 2019

Escaping Alzheimer’s

There is, in Colombia, a family with a tragic legacy of forgetfulness. “People in this large family get Alzheimer’s like clockwork at age 45-50,” said UC Santa Barbara neuroscientist Kenneth S. Kosik, the campus’s Harriman Professor of Neuroscience and co-director of the Neuroscience Research Institute. Their aggressive, genetic form of the […]
November 5, 2019

Researchers discover a way to turn Parkinson protein on itself

Researchers have found a way to create a super-inhibitor that effectively stops the development of Parkinsons by using the Parkinson disease itself as an active building block. Various neurodegenerative diseases such as Parkinson’s are closely linked to the aggregation of individual components called monomers of a specific protein that forms […]
November 5, 2019

Genes from ‘fossil’ virus in human DNA found to be active

Inserted in the human genome thousands of years ago, the genes can produce viral proteins without activating the whole virus. Genes from a virus that was stitched into the human genome thousands of years ago are active, producing proteins in the human brain and other tissues, according to researchers at […]
November 5, 2019

Marker reveals if benign-appearing meningiomas are perilous

A modified protein in benign-appearing meningiomas can reveal which are truly benign and which are more dangerous and require more aggressive treatment, researchers have discovered. The finding may also offer clues as to why these ‘benign’ tumors, which arise from the membranes that surround the brain and spinal cord, start […]
November 5, 2019

Yale Cancer Center study shows checkpoint inhibitor prolongs survival in patients with certain head and neck cancers

The checkpoint inhibitor pembrolizumab (Keytruda) increases the survival time of patients with advanced head and neck cancers, according to a new global study led by Yale Cancer Center (YCC). The data was published in the journal The Lancet. The findings of the phase 3 study show that, compared to the standard […]
November 5, 2019

High-tech foam offers new tool for developing stem cells

Two Florida State University researchers are developing a high-tech material currently used in athletic equipment and prosthetics into a special tool to better develop stem cells. The work could improve drug screening, disease modeling, precision medicine, and cell therapy. FAMU-FSU College of Engineering researchers Yan Li, an associate professor in […]
November 4, 2019

Lab leads effort to model proteins tied to cancer

Computational scientists, biophysicists and statisticians from Lawrence Livermore National Laboratory (LLNL) and Los Alamos National Laboratory (LANL) are leading a massive multi-institutional collaboration that has developed a machine learning-based simulation for next-generation supercomputers capable of modeling protein interactions and mutations that play a role in many forms of cancer. The […]
November 1, 2019

Advanced microscopy reveals unusual DNA structure

Sandia scientist pushes technology’s limits to see fundamental feature of stretched S-DNA. An advanced imaging technique reveals new structural details of S-DNA, ladder-like DNA that forms when the molecule experiences extreme tension. This work conducted at Sandia National Laboratories and Vrije University in the Netherlands provides the first experimental evidence […]
November 1, 2019

Dentists could diagnose dia­betes and pre­dia­betes

Do you know how many people in the world suffer from diabetes? About 422, according to World Health Organization, but we can’t know for certain. The issue here is that many people who are suffering from diabetes live without diagnosis. This is a huge problem, but scientists think that one […]
October 31, 2019

Skeleton Key

Researchers reveal structures of skeletal components in hair-like cilia. It’s not every day that scientists get to publish a paper on Halloween about a skeleton, but that’s what the laboratories of Alan Brown in the Blavatnik Institute at Harvard Medical School and Rui Zhang at Washington University in St. Louis just did. As reported […]
October 31, 2019

3D-Printed Device Finds ‘Needle in a Haystack’ Cancer Cells by Removing the Hay

Finding a handful of cancer cells hiding among billions of blood cells in a patient sample can be like finding a needle in a haystack. In a new approach enabled by 3D-printed cell traps, researchers are removing the hay to expose the cancer cells. Trapping the white blood cells – […]
October 31, 2019

Gabapentinoids Appear Increasingly to be Prescribed, Off-Label, for Cancer Pain

Between 2005 and 2015, as the opioid crisis in America came into focus, prescriptions for gabapentinoid medications — gabapentin and pregabalin — to adults with cancer saw a two-fold increase, a University of Michigan Rogel Cancer Center study has found. Gabapentin, which affects voltage-gated calcium channels in the brain, was originally approved […]
October 30, 2019

How our brains remember things depends upon how we learn them

The researchers from the Department of Experimental Psychology, the Wellcome Centre for Integrative Neuroimaging (WIN) and the Nuffield Department of Clinical Neurosciences, used an MRI scanner to observe changes in parts of the brain associated with learning and learned experiences while volunteers completed tasks that involved a reward. Participants also […]
October 30, 2019

Pediatric cancer study shows usefulness of gene expression analysis

Analyzing gene expression in tumor cells from children with cancer is more likely to reveal targets for therapy than analysis of DNA mutations, according to a new study led by researchers at the UC Santa Cruz Genomics Institute. The study, published in JAMA Network Open, looked at 144 tumor samples from 128 […]
October 30, 2019

Scientists identify critical window for treatment of Alzheimer’s Disease

Neuroscientists at the University of Southampton have made a significant development in understanding how Alzheimer’s disease spreads through the brain, discovering a significant period of time where medical intervention could halt its onset. A hallmark of Alzheimer’s disease is the accumulation of tau protein in neurons which causes loss of […]
October 30, 2019

Study links high-salt diet and cognitive impairment

A high-salt diet may negatively affect cognitive function by causing a deficiency of the compound nitric oxide, which is vital for maintaining vascular health in the brain, according to a new study in mice from Weill Cornell Medicine researchers. When nitric oxide levels are too low, chemical changes to the protein tau […]
October 30, 2019

Mapping cancer’s drug resistance could improve treatment

A set of powerful laboratory and computational techniques developed by scientists at Weill Cornell Medicine and two collaborating centers will enable investigators to map the capacity of tumors to develop resistance to drugs and drug combinations. The techniques – developed with researchers from the New York Genome Center (NYGC) and […]