Related Science News – Page 135 – Innovita Research

Related Science News

March 19, 2021

Mystery of four-stranded DNA begins to unravel

New insights into a little-understood DNA structure could provide the basis for new cancer therapies. DNA is usually depicted as double-stranded, but not much is known about parts of the genome that adopt four-stranded structures known as quadruplexes. UC Riverside researchers have discovered that they play a key role in […]
March 18, 2021

Age-Related Vision Impairment Correlates with Mortality

Researchers here note an association between vision impairment and mortality in later life. This has the look of a correlation that exists because aging is a global process at work throughout the body. It stems from the accumulation of a few classes of cell and tissue damage. That damage causes […]
March 18, 2021

Nanotechnology could enable test for early Alzheimer’s Disease

University of Manchester scientists have discovered previously unseen blood biomarkers which could one day be used to test for Alzheimer’s disease, years before its symptoms appear. The ground-breaking study, published in ACS Nano, used cutting-edge nanotechnology uniquely developed and patented by the Nanomedicine Lab in Manchester, to extract blood signals of […]
March 18, 2021

Study: One enzyme dictates cells’ response to a probable carcinogen

In the past few years, several medications have been found to be contaminated with NDMA, a probable carcinogen. This chemical, which has also been found at Superfund sites and in some cases has spread to drinking water supplies, causes DNA damage that can lead to cancer. MIT researchers have now […]
March 18, 2021

Immune Receptor Protein Could Hold Key to Treatment of Autoimmune Diseases

TARM1 is a receptor protein whose role in the functioning of the immune system is unknown. In a new study, scientists from Japan have explored the potential role of TARM1 in the pathogenesis of rheumatoid arthritis by analyzing mouse models. They found that TARM1 activated dendritic cells, and the development of […]
March 18, 2021

Cancer patients set to benefit from £3.5m funding for cell therapies

CytoSeek’s technology is designed to help target the immune cells to the solid tumour and improve their cancer cell-killing ability. Solid tumours account for the majority of deaths from cancer and are notoriously difficult to treat, even with existing immune cell therapies, because the tumour suppresses immune cells’ ability to […]
March 18, 2021

How sperm remember

It has long been understood that a parent’s DNA is the principal determinant of health and disease in offspring. Yet inheritance via DNA is only part of the story; a father’s lifestyle such as diet, being overweight and stress levels have been linked to health consequences for his offspring. This […]
March 18, 2021

More precise diagnoses made possible with whole genome sequencing

More than 1,200 people with rare diseases have received a diagnosis thanks to the integration of large-scale genomics into the Stockholm region’s healthcare system. This is according to a study from Karolinska Institutet in Sweden that analysed the result of the first five years of collaboration on whole-genome sequencing between […]
March 18, 2021

Escape Artist

The vast majority of people infected with SARS-CoV-2 clear the virus, but those with compromised immunity—such as individuals receiving immune-suppressive drugs for autoimmune diseases—can become chronically infected. As a result, their weakened immune defenses continue to attack the virus without being able to eradicate it fully. This physiological tug-of-war between […]
March 17, 2021

Supercomputing the secrets of the inner ear

The ears don't just help you hear. They also help a person walk, stand, and stay balanced. In fact, they work together with other systems in the body to help one understand our place in space. Many people who have sensations of vertigo find that the problem lies in their […]
March 17, 2021

Stem cell scientists start a buzz around fruit flies in hearing research

Even though a fruit fly doesn’t have ears, it can hear with its antennae. In a study published in the journal Development, USC Stem Cell scientists describe how adult flies can regenerate sensory hearing cells in their antennae, and how studying flies can provide a new way to understand and […]
March 17, 2021

Supercomputers Help Accelerate Alzheimer’s Research

Since 2009, Daniel Tward and his collaborators have analyzed more than 47,000 images of human brains via MRI Cloud—a gateway created to collect and share quantitative information from human brain images, including subtle changes in shape and cortical thickness. The latter was the topic of a recently published study in the […]
March 17, 2021

How to Speed Up Muscle Repair

A study led by researchers at the University of California San Diego Jacobs School of Engineering provides new insights for developing therapies for muscle disease, injury and atrophy. By studying how different pluripotent stem cell lines build muscle, researchers have for the first time discovered how epigenetic mechanisms can be […]
March 17, 2021

Researchers link breast cancer and bone growth

Breast cancer poses a substantial threat as it spreads to other organs, often lying in wait for years in these tissues and recurring without warning. Bones are a prime target, but the mechanisms that influence whether skeletal metastasis will develop or not remain poorly understood. A collaboration between researchers at […]
March 17, 2021

Stimulating the Immune System to Fight Cancer

Cancer cells have evolved mechanisms to escape the body's immune defense. Agents that prevent immune escape are attractive targets for the development of new cancer therapies. A group of scientists led by Herbert Waldmann and Slava Ziegler at the Max Planck Institute of Molecular Physiology in Dortmund has now developed […]
March 17, 2021

Piperlongumine Reduces Aortic Calcification in Mice

Piperlongumine, an extract of long peppers, was shown to be senolytic a few years ago. The compound is capable of selectively destroying senescent cells by sensitizing them to oxidative damage, provoking apoptosis. The accumulation of senescent cells is one of the causes of aging, and means of clearance are thus […]
March 17, 2021

Inclusive Autism Screening

Screening tools for autism spectrum disorder (ASD) often fail to identify ASD among children from low-income families and racial/ethnic minority groups, particularly when English is not the family’s primary language. A new visually-based tool may reduce these disparities at a pivotal point in children’s development. In Pediatrics, Zuleyha Cidav, David Mandell, and colleagues found […]
March 17, 2021

Head Injury 25 Years Later – Study Finds Increased Risk of Dementia

Head injury in the United States is common, with over 23 million adults age 40 or older reporting a history of head injury with loss of consciousness. Many head injuries can be caused by a host of different situations – from car and motorcycle accidents to sports injuries. What’s more, it […]
March 17, 2021

Babies pay attention with down payment from immature brain region

Anyone who has watched an infant’s eyes follow a dangling trinket dancing in front of them knows that babies are capable of paying attention with laser focus. But with large areas of their young brains still underdeveloped, how do they manage to do so? Using an approach pioneered at Yale […]
March 17, 2021

94% of older adults prescribed drugs that raise risk of falling

Nearly every older adult has prescribed a prescription drug that increased their risk of falling in 2017, according to new University at Buffalo research. The study found that the percentage of adults 65 and older who were prescribed a fall- risk-increasing drug climbed to 94% in 2017, a significant leap […]
March 16, 2021

International Alzheimer’s clinical trial to test tau drugs

A worldwide clinical trial aimed at finding treatments for Alzheimer’s disease has expanded to include investigational drugs targeting a harmful form of the brain protein tau. The trial, known as the Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) and led by Washington University School of Medicine in St. Louis, launched […]
March 16, 2021

Different Strokes for Stem Cells

New software advances ability to turn stem cells into other cell types. Harvard Medical School researchers and colleagues have developed new software to help scientists generate different types of cells for use in research and medicine. The software aids ongoing efforts to turn induced pluripotent stem cells, or IPSCs—adult cells that […]
March 16, 2021

Ultrasound reveals the human brain vasculature down to the microscopic scale

Mapping the cerebral vascular network in human patients, at unprecedented scales: this tour de force has been achieved by the French laboratory Physics for Medicine Paris (ESPCI Paris-PSL, Inserm, CNRS). In a study published on the front page of Nature Biomedical Engineering, the research team details its method: ultrasound localization […]
March 16, 2021

Elusive Protein Complex Could Hold the Key to Treating Chromosomal Disorders

Scientists report on the structural and molecular factors governing the stability of a protein complex involved in DNA repair pathways in cells. The cells in our body are constantly fighting off the threat of cancer by repairing damaged DNA. In a new study, scientists from Tokyo University of Science investigate […]
March 15, 2021

Metabolic derangements caused by a high-fat diet may be possible to eliminate

Intake of a high-fat diet leads to an increased risk for obesity, type 2 diabetes, cardiovascular diseases and fatty liver. A study in mice from Karolinska Institutet shows that it is possible to eliminate the deleterious effects of a high-fat diet by lowering the levels of apolipoprotein CIII (apoCIII), a […]
March 15, 2021

Accurate Aging of Wild Animals Thanks to First Epigenetic Clock for Bats

New research by the University of Bristol as part of a team led by the University of Maryland (UMD) identifies age-related changes to DNA, revealing longevity-related differences among bat species. The study found that DNA from tissue samples can be used to accurately predict the age of bats in the […]
March 15, 2021

How Useful is Next-Generation Sequencing for Patients with Advanced Cancer?

Patients with cancers of unknown origin greatly benefited from next-generation sequencing; widespread inherited cancer risk also suggests broad utility, a study finds. When standard cancer treatments don’t work, or if doctors can’t determine where a patient’s cancer originated, genomic sequencing can help pinpoint mutations in a tumor that might be […]
March 15, 2021

Extra signal in brain helps form new memories, but impairs long-term recall

Mouse study focuses on signal from astrocytes to nerves. Researchers were able to enhance memory formation in mice by increasing a specific signal between astrocytes, one of the most numerous types of cell in the brain that occupy more space in the brain than nerve cells. Experts have long known […]