Related Science News – Page 13 – Innovita Research

Related Science News

May 30, 2021

Switching off heart protein could protect against heart failure

Switching off a heart muscle protein could provide a new way for drugs to combat heart failure in people who’ve had a heart attack, according to research led by the University of Cambridge and published in the journal Nature. There is an unmet need to find drugs that can successfully improve […]
May 30, 2021

Many of us could carry up to 17kg of fat due to a change in a single gene

New research has found that one in every 340 people might carry a mutation in a single gene that makes them more likely to have a greater weight from early childhood and, by 18 years of age, they could be up to 30 pounds heavier with the excess weight likely […]
May 30, 2021

AI technique detects cancer ‘drivers,’ ‘passengers’

Scientists have made major advances in understanding and developing treatments for many cancers by identifying genetic mutations that drive the disease. Now, a team led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and the New York Genome Center (NYGC) has developed a machine learning technique for detecting other modifications to DNA that have a […]
May 30, 2021

Solving the Peroxisome Puzzle

The ability to make membrane-bound organelles is a defining characteristic of eukaryotic cells — cells that constitute the bodies of all animals, plants and fungi on Earth. Membranes create enclosures that provide specialized environments for certain structures and their functions, such as the nuclei that store genetic information, or the […]
May 30, 2021

Tiniest of moments proves key for baby's healthy brain

University of Virginia School of Medicine researchers have shed new light on how our brains develop, revealing that the very last step in cell division is crucial for the brain to reach its proper size and function. The new findings identify a potential contributor to microcephaly, a birth defect in […]
May 29, 2021

Researchers reveal key information about how genes turn on and off

Human bodies have roughly 30,000 genes dictating not only how we look, but also critical biological processes. Now, a Florida State University and Australia National University research team has discovered a key aspect of gene regulation and ultimately how that process is implicated in cancer. Jonathan Dennis, an associate professor […]
May 29, 2021

Researchers create cellular blueprint of healthy lungs

The primary function of the lung is to facilitate the transfer of oxygen to the bloodstream. Crucial to this lifegiving task are endothelial cells, which line blood vessels permeating the lung and through which gas exchange occurs. Malfunction of these cells is implicated in a range of different diseases, including […]
May 29, 2021

Brain injury research to focus on moderate concussion

Viji Santhakumar, an associate professor of molecular, cell and systems biology at the University of California, Riverside, has received funding from the National Institute of Neurological Disaster and Stroke of the National Institutes of Health to further pursue research on moderate concussive brain injury, which results from car accidents or sports-related concussions. […]
May 28, 2021

Head and neck cancer cells hijack nearby healthy tissue, promoting further invasion of cancer cells

Up to half of patients with head and neck squamous cell carcinoma will experience tumor recurrence or new tumors—tumors that often spread and are difficult to treat. A team of scientists led by the University of Michigan School of Dentistry identified a mechanism by which head and neck cancer cells […]
May 28, 2021

Final results of SPRINT study confirm controlling blood-pressure critically important in preventing heart disease and stroke

Follow-up data from the landmark SPRINT study of the effect of high blood pressure on cardiovascular disease have confirmed that aggressive blood-pressure management—lowering systolic blood pressure to less than 120 mm Hg—dramatically reduces the risk of heart disease, stroke and death from these diseases, as well as death from all […]
May 28, 2021

Immediate skin-to-skin contact after birth improves survival of pre-term babies

Continuous skin-to-skin contact starting immediately after delivery even before the baby has been stabilised can reduce mortality by 25 per cent in infants with very low birth weight. This according to a study in low- and middle-income countries coordinated by the WHO on the initiative of researchers at Karolinska Institutet […]
May 28, 2021

Smoking during pregnancy associated with child’s risk of having congenital heart disease

Children born to mothers who smoked during pregnancy were at increased risk of having congenital heart disease, a new study published in the Journal of the American Heart Association has found. The study was led by the University of Bristol, in an international collaboration with researchers from seven institutions. It […]
May 28, 2021

Many of us could carry extra fat due to a change in a single gene

New research has found that one in every 340 people might carry a mutation in a single gene that makes them more likely to have a greater weight from early childhood and, by 18 years of age, they could be up to 30 pounds heavier with the excess weight likely […]
May 28, 2021

Cardiac MRI effective in detecting asymptomatic, symptomatic myocarditis in athletes

A cardiac MRI of athletes who had COVID-19 is seven times more effective in detecting inflammation of the heart than symptom-based testing, according to a study led by researchers at The Ohio State University Wexner Medical Center and College of Medicine with 12 other Big Ten programs. The findings are published online by JAMA Cardiology. The […]
May 28, 2021

When cancer cells “put all their eggs in one basket”

Normal cells usually have multiple solutions for fixing problems. For example, when DNA becomes damaged, healthy white blood cells can use several different strategies to make repairs. But cancer cells may “put all their eggs in one basket,” getting rid of all backup plans and depending on just one pathway […]
May 27, 2021

Engineered organism could diagnose Crohn's disease flareups

In an important step toward the clinical application of synthetic biology, Rice University researchers have engineered a bacterium with the capability of diagnosing a human disease. An engineered strain of the gut bacteria E. coli senses pH and glows when it encounters acidosis, an acidic condition that often occurs during flareups of inflammatory bowel […]
May 27, 2021

Scientists discover brain cells that compete to sustain or suppress traumatic memories

Two clusters of brain cells compete to promote either the persistence or disappearance of traumatic memories, according to a new study conducted in mice. The findings could provide important insights into human conditions such as post-traumatic stress disorder (PTSD), anxiety disorders, and associated problems such as alcohol use disorder (AUD) […]
May 26, 2021

Mothers can influence offspring’s height, lifespan and disease risk in unexpected ways – through their mitochondria

Mitochondria –  the ‘batteries’ that power our cells – play an unexpected role in common diseases such as type 2 diabetes and multiple sclerosis, concludes a study of over 350,000 people conducted by the University of Cambridge. The study, published in Nature Genetics, found that genetic variants in the DNA […]
May 26, 2021

Protein simulation, experiments unveil clues on origins of Parkinson's disease

Parkinson’s disease is the second most common neurodegenerative disease and affects more than 10 million people around the world. To better understand the origins of the disease, researchers from Penn State College of Medicine and The Hebrew University of Jerusalem have developed an integrative approach, combining experimental and computational methods, to understand how individual […]
May 26, 2021

Researchers use ‘hole-y’ math and machine learning to study cellular self-assembly

A new study shows that mathematical topology can reveal how human cells organize into complex spatial patterns, helping to categorize them by the formation of branched and clustered structures. The field of mathematical topology is often described in terms of donuts and pretzels. To most of us, the two differ […]
May 26, 2021

Commonly Used Drugs for Schizophrenia Linked to Greater Cognitive Impairment

Writing in the journal The American Journal of Psychiatry, a multi-institution team of scientists led by researchers at University of California San Diego School of Medicine report that medications commonly prescribed to reduce the severity of physical and mental health symptoms associated with schizophrenia may have a cumulative effect of […]
May 26, 2021

Older Adults with Functional Impairments Linked to Prescription Drug Use/Misuse

According to the Centers for Disease Control and Prevention, approximately 22 percent of older adults in the United States suffer from a functional impairment, defined as difficulties performing daily activities, such as bathing or getting dressed, or problems with concentration or decision-making affected by physical, mental or emotional conditions. In […]
May 26, 2021

Genetic Tools Help Identify a Cellular Culprit for Type 1 Diabetes

By mapping its genetic underpinnings, researchers at University of California San Diego School of Medicine have identified a predictive causal role for specific cell types in type 1 diabetes, a condition that affects more than 1.6 million Americans. The findings were published in the journal Nature. Type 1 diabetes is […]
May 26, 2021

Metabolic hormone ‘leptin’ linked to vaccine response

Reduced levels of a metabolic hormone known as leptin is linked to poor vaccine antibody responses in the general population, a University of Queensland study has found. The researchers made the discovery while investigating several cohorts’ responses to the influenza vaccine or hepatitis B vaccine pre-COVID. UQ’s Professor Di Yu […]
May 26, 2021

Case Western Reserve-led research team aims to determine which diabetic individuals can successfully donate corneas for transplant (and which should not)

About a third of the corneal transplant surgeries in the United States involve people with diabetes who donate their corneas after death. The number of corneal transplants has grown over the last decade, but through continuous research, the medical community has learned that not all corneal tissue from diabetics may […]
May 26, 2021

In vivo drug discovery for β-cell proliferation in diabetes

In a study published in Nature Metabolism, researchers at the Department of Cell and Molecular Biology developed a novel technique to identify small molecules that can make insulin-producing β-cells divide. Olov Andersson and Jeremie Charbord explain: Diabetes is characterized by the progressive loss of functional β-cells. One possible approach to curing diabetes is […]
May 26, 2021

Electrical nerve stimulation research could pave the way to new treatments

A project to measure the effects of electrical stimulation of a major nerve that could hold the key to new treatments for a range of diseases from epilepsy to depression is underway at the University of Bath. Members of C3Bio, the University’s Centre for Biosensors, Bioelectronics and Biodevices, are working to […]
May 26, 2021

Microglia Become More Pro-Inflammatory in the Aging Brain

In this open access commentary, the authors discuss efforts to uncover the mechanisms by which microglia in the aging brain are primed to undertake inflammatory responses, more so than those in the young brain. This may be due in part towards increased numbers of senescent microglia, secreting pro-inflammatory signals. This […]
May 26, 2021

New findings to boost IVF success rates

In vitro fertilization fulfils the wishes of half a million parents each year, yet fertility treatment leaves plenty of room for improvement. A majority of potential embryos are ruled out for implantation, flagged by a genetic test designed to root out abnormalities early on.  This selection process limits the success […]
May 26, 2021

New wiki on salivary proteins may transform diagnostic testing and personalized medicine

To improve the development of new saliva-based diagnostic tests and personalized medicine, the National Institute of Dental and Craniofacial Research (NIDCR) has supported the development of the Human Salivary Proteome Wiki, the first public platform that catalogues and curates data on each of the thousands of proteins within our saliva. Detailed […]