Related Science News – Page 195 – Innovita Research

Related Science News

January 17, 2020

Hormone resistance in breast cancer linked to DNA ‘rewiring’

Epigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatment for ER+ breast cancer, which accounts for 70% of all diagnoses. Reversing these changes, researchers say, has significant potential to help reduce breast cancer relapse. A team led by […]
January 16, 2020

Genome editing at the crossroads of scandal and cure

Genetic modification of babies in China one year ago was universally condemned. At the same time, CRISPR treatments are on their way into our clinics. Jacob Corn explains the difference. A huge outcry broke out a year ago when Chinese researcher He Jiankui announced at a conference that he had […]
January 16, 2020

BPA activates immune response in mice that passes down through generations

Some plastic food and beverage containers still contain bisphenol A (BPA), which can mimic the hormone estrogen. Although experts say that small amounts of BPA detected in foods are unlikely to cause problems, some people worry that constant low-level exposures could have health effects, especially for developing fetuses, infants and […]
January 16, 2020

New Mechanisms Describe How the Genome Regulates Itself

An organism's genome contains all of the information necessary for each of its cells and tissues to develop and function properly. Written in DNA, each individual gene encodes for something, whether it is a structural protein that helps define a tissue's shape, an enzyme that catalyzes the chemical reactions of […]
January 16, 2020

Mutations in donors’ stem cells may cause problems for cancer patients

A stem cell transplant — also called a bone marrow transplant — is a common treatment for blood cancers, such as acute myeloid leukemia (AML). Such treatment can cure blood cancers but also can lead to life-threatening complications, including heart problems and graft-versus-host disease, in which new immune cells from […]
January 16, 2020

Study Paves Way for New Vaccines to Protect Infants Against Infections

A new Penn Medicine study puts researchers within closer reach of vaccines that can protect infants against infections by overcoming a mother’s antibodies, which are known to shut down immune defenses initiated by conventional vaccines. That hurdle largely explains why vaccinations for infectious diseases like influenza and measles not given until […]
January 16, 2020

Use of hormone provides no neuroprotection in preemies

A study published in the  New England Journal of Medicine suggests that erythropoietin treatment may not provide neuroprotection for extremely premature babies. This multicenter study was led by Sandra E. Juul, professor of pediatrics  and head, Division of Neonatology, at the University of Washington School of Medicine in Seattle. The researchers randomized more […]
January 15, 2020

A Simple Twist of Cell Fate

How do a couple of universally expressed proteins in stem cells and developing embryos influence an individual cell’s ultimate fate — whether it ultimately becomes, for example, a retinal cell, a heart muscle cell, or a stomach lining cell? That’s the question that Rajesh C. Rao, M.D., and his colleagues at […]
January 15, 2020

Cancer’s big appetite

THERE’S NO SHORTAGE of ways to kill a cancer cell. Cut it out, poison it, blast it with radiation, shower it with killer immune cells—they all get the job done. But there is a shortage of good ways to kill cancer cells. One that knocks out all the bad cells in one swipe, […]
January 15, 2020

Brain Tumor Organoids May be Key to Time-sensitive Treatments for Glioblastomas

Lab-grown brain organoids developed from a patient’s own glioblastoma, the most aggressive and common form of brain cancer, may hold the answers on how to best treat it. A new study in Cell from researchers at Penn Medicine showed how glioblastoma organoids could serve as effective models to rapidly test personalized treatment […]
January 14, 2020

Investigational drugs block bone loss in mice receiving chemotherapy

Bone loss that can lead to osteoporosis and fractures is a major problem for cancer patients who receive chemotherapy and radiation. Since the hormone estrogen plays an important role in maintaining bone health, bone loss is especially pronounced among postmenopausal women with breast cancer who are treated using therapies aimed […]
January 13, 2020

Researchers Identify Cellular Pathways that Extend Lifespan by 500%

Working on C. elegans – a nematode worm commonly used in aging research due to its weeks-long lifespan and genetic similarities with humans – an international team of researchers from the U.S. and China have identified synergistic cellular pathways for longevity which can extend the host’s lifespan by as many […]
January 13, 2020

U-M Team Sheds New Light on the Role of Regulatory T Cells in Pancreatic Cancer

A multidisciplinary Michigan Medicine team is shedding new light on the role of regulatory T cells in pancreatic cancer — and, in mouse models, have uncovered a new potential target to improve immunotherapy approaches to the deadly disease. Regulatory T cells are a subpopulation of immune cells that help keep […]
January 13, 2020

Genetic Testing: Advantages and Limitations

DNA testing has become one of the most valuable tools that humans can rely on to discover possible traits and limitations. Simply put, DNA is the code in our cells, the most complex and richest piece of information we have about our existence. Genetic testing helped us identify changes in […]
January 3, 2020

When you eat might be as important as what you eat

During the years 1976 through 1980, 15% of U.S. adults were obese. Today, about 40% of adults are obese. Another 33% are overweight. Coinciding with this increase in weight are ever-rising rates of heart disease, diabetes, cancer and health complications caused by obesity, such as hypertension. Even Alzheimer’s disease may […]
January 3, 2020

Versatile bile acids

Could bile acids—the fat-dissolving juices churned out by the liver and gallbladder—also play a role in immunity and inflammation? The answer appears to be yes, according to two separate Harvard Medical School studies published in Nature. The findings of the two studies, both conducted in mice, show that bile acids promote […]
January 3, 2020

Redefining Sexual Identity with Parkinson’s Disease

Discussions about sexual health can be awkward, but for Daniela Wittmann, Ph.D., MSW, they go with the territory. As a social certified sex therapist, she sees patients with sexual health issues at the Michigan Medicine Center for Sexual Health and in the Department of Urology. She also discusses these types of issues with Parkinson’s disease patients during […]
January 2, 2020

Closer to identifying leukemic stem cells

Acute myeloid leukaemia is the most common type of leukaemia in adults. It is characterized by the pathological expansion of immature cells (myeloblasts) that invade the bone marrow and expand into the blood, affecting the production of the rest of the healthy cells. Although patients usually respond well to chemotherapy-based […]
January 2, 2020

New treatment for heart attack scar could address heart failure

Heart disease remains the largest killer in Australia and around the world. A new study has shown that a protein therapy– recombinant human platelet-derived growth factor-AB (rhPDGF-AB) – could improve outcomes following heart attack. After a heart attack, scar tissue forms and this negatively affects heart function. Now, researchers from […]
January 2, 2020

Short or long sleep associated with Pulmonary Fibrosis

Scientists have discovered that people who regularly sleep for more than 11 hours or less than 4 hours are 2-3 times more likely to have the incurable disease, pulmonary fibrosis, compared to those that sleep for 7 hours in a day. They attribute this association to the body clock. The […]
January 2, 2020

Alzheimer ‘Tau’ Protein Far Surpasses Amyloid in Predicting Toll on Brain Tissue

Brain imaging of pathological tau-protein “tangles” reliably predict the location of future brain atrophy in Alzheimer’s patients a year or more in advance, according to a new study by scientists at the UC San Francisco Memory and Aging Center. In contrast, the location of amyloid “plaques,” which have been the […]
December 31, 2019

Developmental changes in the brain may influence how often adolescents get drunk

A new study led by researchers at King’s College London has found that adolescents with particular patterns of brain development report an increased frequency in drunkenness. The research was published in JAMA Psychiatry. Using brain imaging data collected from 726 healthy adolescents, the researchers analysed changes in the volume of […]
December 31, 2019

Study finds potential link between cardiovascular death and some types of pesticides

A new study from the University of Iowa suggests that people who have higher levels of a chemical in their body that indicates exposure to commonly used insecticides die of cardiovascular disease at a significantly higher rate. Findings from the study, published in the journal JAMA Internal Medicine, suggest those who have […]