Related Science News

April 2, 2021

Pancreatic Cancer Cells Hijack Muscle Protein to Beef Up Their Metabolism

Cancer starts with mutations in a cell’s DNA, but new UC San Francisco research shows that the endurance of a tumour relies on its ability to rapidly evolve and adapt to challenges brought about by the environment in which it grows. “A major obstacle cancer cells must overcome is their […]
April 2, 2021

Mice naturally engage in physical distancing, study finds

When someone is sick, it’s natural to want to stay as far from them as possible. It turns out this is also true for mice, according to an MIT study that also identified the brain circuit responsible for this distancing behaviour. In a study that explores how otherwise powerful instincts […]
April 2, 2021

Disrupted biochemical pathway in the brain linked to bipolar disorder

Bipolar disorder affects millions of Americans, causing dramatic swings in mood and, in some people, additional effects such as memory problems. While bipolar disorder is linked to many genes, each one making small contributions to the disease, scientists don’t know just how those genes ultimately give rise to the disorder’s […]
April 2, 2021

How industrialized life remodels the microbiome

Thousands of different bacterial species live within the human gut. Most are beneficial, while others can be harmful. A new study from an MIT-led team has revealed that these bacterial populations can remake themselves within the lifetime of their host, bypassing genes back and forth. The researchers also showed that […]
April 1, 2021

Preventive treatment reduces diabetic retinopathy complications

In a clinical trial, early treatment with anti-vascular endothelial growth factor (VEGF) injections slowed diabetic retinopathy, a complication of diabetes that causes damage to the blood vessels of the light-sensitive tissue in the retina. However, two years into the four-year study, the early treatment’s effect on vision – including changes […]
April 1, 2021

Chemo for glioblastoma may work better in morning than evening

An aggressive type of brain cancer, glioblastoma has no cure. Patients survive an average of 15 months after diagnosis, with fewer than 10% of patients surviving longer than five years. While researchers are investigating potential new therapies via ongoing clinical trials, a new study from Washington University in St. Louis […]
April 1, 2021

Developing a new platform for DNA sequencing

New research from the lab of Marija Drndić showcases a potential new platform for parallel DNA sequencing. Published in The Journal of Chemical Physics, the study uses state-of-the-art fabrication and analytical techniques and demonstrates a path to how solid-state materials can be further developed for high-throughput sequencing. The research was conducted by Drndić, PhD […]
April 1, 2021

Study: Stem Cell Transplants Prevent Relapses of Most Common Childhood Cancer

Children and young adults who receive CAR T-cell therapy for the most common childhood cancer, acute lymphoblastic leukaemia, suffer remarkably fewer relapses and are far more likely to survive when the treatment is paired with a subsequent stem cell transplant, a new study finds. The research, with an average, follow […]
April 1, 2021

UO lab advances research on memory formation and recall

Difficulty remembering a password or where a car is parked outside a store doesn’t necessarily suggest memory problems. It’s likely that interference is clouding the brain, suggests University of Oregon neuroscientist Brice Kuhl. How do people encode new information and accurately recall it later? That’s the focus of the Kuhl […]
April 1, 2021

Sugar not so nice for your child’s brain development

Sugar practically screams from the shelves of your grocery store, especially those products marketed to kids. Children are the highest consumers of added sugar, even as high-sugar diets have been linked to health effects like obesity and heart disease and even impaired memory function. However, less is known about how […]
March 31, 2021

COVID-19 increases allure of at-home colon cancer tests

A year ago, when the COVID-19 lockdown began, Dr. Rachel Issaka expected that colonoscopies would decline. She was surprised by how much. In the first two months, in-clinic colon cancer screenings fell by 90%.  “I was shocked,” said Issaka, a UW Medicine gastroenterologist and researcher with the Fred Hutchinson Cancer Research Center. There […]
March 31, 2021

Cancer: a bitter disease that thrives in a bitter environment

When cancer invades the brain, normal salt levels are quickly thrown off-kilter, but detecting this change in patients has been difficult. A team of Yale researchers has developed a non-invasive way to observe these changes in close detail at the early stages of cancer growth. This method, developed in the […]
March 31, 2021

New research on vitamin D and respiratory infections important for risk groups

Earlier studies have shown that supplementary vitamin D seems to provide a certain degree of protection against respiratory infections. A new study involving researchers from Karolinska Institutet has now made the most comprehensive synthesis to date of this connection. The study, which is published in the journal Lancet Diabetes & […]
March 31, 2021

T cells recognize recent SARS-CoV-2 variants

When variants of SARS-CoV-2 (the virus that causes COVID-19) emerged in late 2020, concern arose that they might elude protective immune responses generated by prior infection or vaccination, potentially making re-infection more likely or vaccination less effective. To investigate this possibility, researchers from the National Institute of Allergy and Infectious […]
March 31, 2021

Penn Medicine Researchers Reveal How a Cell Mixes its Mitochondria Before It Divides

In a landmark study, a team led by researchers at the Perelman School of Medicine at the University of Pennsylvania has discovered—and filmed—the molecular details of how a cell, just before it divides in two, shuffles important internal components called mitochondria to distribute them evenly to its two daughter cells. […]
March 31, 2021

Turning back the clock on a severe vision disorder

Gustavo Aguirre and William Beltran, veterinary ophthalmologists and vision scientists at the University of Pennsylvania School of Veterinary Medicine, have studied a wide range of different retinal blinding disorders. But the one caused by mutations in the NPHP5 gene, leading to a form of Leber congenital amaurosis (LCA), is one of the most severe. […]
March 31, 2021

NeuroBasis, a new multi-institution project, is launched

As the ability of medicine to diagnose diseases expands, so does the need for science to decipher their causes. To that end, a team of neuroscientists at the Montreal Clinical Research Institute, affiliated with Université de Montréal, has launched a new project called NeuroBasis. It’s an $8M, a multi-institution collaboration […]
March 31, 2021

A new way to visualize mountains of biological data

Researchers led by the University of Missouri create a new method for analyzing large amounts of biological data to help scientists draw faster conclusions for possible treatments. Studying genetic material on a cellular level, such as single-cell RNA-sequencing, can provide scientists with a detailed, high-resolution view of biological processes at […]
March 31, 2021

Researchers craft AI-based tool that detects bipolar disorder at earlier stages

Many people with early-stage or first-episode bipolar disorder have cognitive deficits, such as issues with visual processing and spatial memory, but those deficits are often so subtle that the disorder can go undiagnosed for years. That could change thanks to researchers at the University of Alberta who have created a […]
March 31, 2021

Study Illuminates the Molecular Details of Lung Development

Researchers at the Perelman School of Medicine at the University of Pennsylvania have produced a detailed molecular atlas of lung development, which is expected to be a fundamental reference in future studies of mammalian biology and of new treatments for diseases, such as COVID-19, that affect the lungs. The researchers, […]
March 31, 2021

Study identifies potential biomarkers for cognitive struggles after surgery

But up to half of older patients undergoing surgery face a lesser-known but similarly formidable cognitive challenge: postoperative delirium, a condition triggered by a surgery that requires anaesthesia and whose trademarks are confusion, disturbed mental faculties, loss of orientation and anxiety. In the worst cases, postoperative delirium leads to extended […]
March 30, 2021

Study shows loss of gene function is causal to congenital heart disease

A team of researchers co-led by Michael Frohman of Stony Brook University has identified an important cause of congenital heart disease. The researchers discovered that certain loss of functions in the PLD1 (phospholipase D1) gene causes congenital right-sided cardiac valve defects and neonatal cardiomyopathy. The findings are detailed in a paper in […]
March 30, 2021

New anticancer drug targets low-oxygen environment of solid tumors

Researchers are perfecting a new generation of anticancer drugs that will be able to specifically target the low-oxygen environment of solid tumors. So far, the new drug has been tested in preliminary experiments with human tumors transplanted into otherwise healthy adult mice. Low oxygen levels among the densely packed cells […]
March 29, 2021

Prior COVID infection primes immune response to one dose of Pfizer/BioNTech vaccine

People previously infected with SARS-CoV-2 show significantly higher T cell and antibody responses following a single dose of Pfizer/BioNTech vaccine compared with uninfected individuals, a collaborative study involving University of Liverpool researchers has found, While both groups show robust immune responses after one dose, the higher response experienced by previously […]
March 29, 2021

ORNL meets key FDA milestone for cancer-fighting Ac-225 isotope

A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs. The U.S. Food and Drug Administration recently acknowledged receipt of Oak Ridge National Laboratory’s drug master file for actinium-225 nitrate, which enables pharmaceutical companies to reference the document to […]
March 28, 2021

Common Alzheimer’s treatment linked to slower cognitive decline

Cholinesterase inhibitors are a group of drugs recommended for the treatment of Alzheimer’s disease, but their effects on cognition have been debated and few studies have investigated their long-term effects. A new study involving researchers from Karolinska Institutet and published in the journal Neurology shows persisting cognitive benefits and reduced […]