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UCLA scientists report that amyloid fibrils found in people with frontotemporal degeneration contain the little-known protein TMEM106B. Scientists have known for years that amyloid fibrils — fibrous, ropelike structures formed by closely linked protein molecules — are present in the brains of patients with Alzheimer’s and Parkinson’s diseases and likely […]

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The key to weight and fat loss

It is widely assumed that the fundamental cause of obesity is an energy imbalance between calories consumed and calories expended (”Calories In, Calories Out”). According to known laws of physics, however, this century-old obesity paradigm must be fallacious. The relevant physical law in terms of body mass regulation is the […]

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