Related Science News

August 4, 2021

Delivery of α-klotho as a Basis for Neuroprotective Treatments

Klotho is one of the few well-established longevity-associated genes that works in both directions in animal models: less klotho shortens life span, while more klotho extends life. Klotho also improves cognitive function. The mechanisms by which klotho produces these outcomes remain poorly understood: there is the usual grab-bag of identified […]
August 2, 2021

How neurons get past “no”

Inhibitory neurons target the weakest-responding neurons in the brain to facilitate transmission of signals. When looking at a complex landscape, the eye needs to focus in on important details without losing the big picture—a charging lion in a jungle, for example. Now, a new study by Salk scientists shows how […]
August 2, 2021

How plants quickly adapt to shifting environmental conditions

Salk scientists find that canopy shade from competing plants triggers cellular changes in as little as five minutes. Scientists and gardeners have long known that plants grow taller and flower sooner when they are shaded by close-growing neighbors. Now, for the first time, researchers at the Salk Institute have shown […]
August 2, 2021

Researchers find molecular switch that regulates fat burning in mice

Linked to serious health problems including cancer, diabetes and cardiovascular disease, obesity affects more than a third of adults in the United States. Presently, there are few safe and effective nonsurgical therapeutic interventions available to patients with obesity.  Now, a multi-disciplinary team of researchers has demonstrated that a metabolic regulatory […]
August 1, 2021

Histopathology driven artificial intelligence predicts TMB-H colorectal cancer

Biomarkers are important determinants of appropriate and effective therapeutic approaches for various diseases including cancer. There is ample evidence pointing toward the significance of immune check point inhibitors (ICI) against cancer, and they showed promising clinical benefits to a specific group of patients with colorectal cancer (CRC). Several reports demonstrated […]