Related Science News – Page 12 – Innovita Research

Related Science News

April 15, 2020

3D imaging of blood vessels could shed new light on cardiovascular disease

Cardiovascular disease is often the result of blood vessels becoming clogged by plaques—buildups of fat, calcium, and other substances that may restrict blood flow. Not every plaque is created equal, however; some are more likely to induce a heart attack or stroke than others. Now a new three-dimensional imaging technique […]
April 15, 2020

Diet may help preserve cognitive function

According to a recent analysis of data from two major eye disease studies, adherence to the Mediterranean diet – high in vegetables, whole grains, fish, and olive oil – correlates with higher cognitive function. Dietary factors also seem to play a role in slowing cognitive decline. Researchers at the National […]
April 15, 2020

Study tracks genomics of lung tumor behavior

A study by Vanderbilt researchers has identified genomic alterations in early-stage adenocarcinomas of the lung that may indicate whether the lesions develop into aggressive tumors. The study published in the American Journal of Respiratory and Critical Care Medicine is the largest analysis of in situ and early adenocarcinomas lesions using targeted sequencing. […]
April 15, 2020

Large-scale analysis links glucose metabolism proteins in the brain to Alzheimer’s disease biology

In the largest study to date of proteins related to Alzheimer’s disease, a team of researchers has identified disease-specific proteins and biological processes that could be developed into both new treatment targets and fluid biomarkers. The findings suggest that sets of proteins that regulate glucose metabolism, together with proteins related to […]
April 15, 2020

Tailoring treatment for triple-negative breast cancer

Immunotherapies have revolutionized treatment for people with a variety of cancers. But when given to those with triple-negative breast cancer (TNBC), a particularly aggressive form of the disease, less than 20% respond. “A big question in the field has been, Why are the rest not responding?” says Rumela Chakrabarti, an assistant […]
April 14, 2020

Therapies show knockout potential for rare, deadly liver cancer

A new study identifies some of the most critical genes that may drive a rare but deadly liver cancer, providing a road map for developing drugs that target those genes. The cancer, fibrolamellar carcinoma, accounts for 1-5% of all liver cancers, and disproportionately affects children and young adults. By the […]
April 14, 2020

New research gives insights into how a group of novel organelle-based disorders affects cells

A pioneering study has shed new light on how a group of novel organelle-based disorders affect cells. The study led by Professor Michael Schrader from the University of Exeter, and featuring an international, multi-disciplinary team of scientists, has explored on peroxisome alterations and their contribution to the disease. Organelles are the functional units […]
April 14, 2020

New study shows how oxygen transfer is altered in diseased lung tissue

A multidisciplinary team of researchers at the University of Illinois at Urbana-Champaign has developed tiny sensors that measure oxygen transport in bovine lung tissue. The study – which establishes a new framework for observing the elusive connection between lung membranes, oxygen flow and related disease – was published in the […]
April 14, 2020

Switching on a key cancer gene could provide first curative treatment for heart disease

Researchers trying to turn off a gene that allows cancers to spread have made a surprising U-turn. By making the gene overactive and functional in the hearts of mice, they have triggered heart cell regeneration. Since adult hearts cannot usually repair themselves once damaged, harnessing the power of this gene […]
April 14, 2020

Researchers Uncover Importance of Aligning Biological Clock with Day-Night Cycles

Timing is everything. A fresh example supporting the old saying has been found in connection with the systems regulated by biological clocks. Research on circadian rhythms, our internal 24-hour patterns that affect sleep-wake and metabolic cycles, has shown that timing is key for human health. When our activities and internal […]
April 14, 2020

Technique tracks gene expression changes as cells change

A new technique makes it possible to track changes in gene activity across a cell’s entire genome over time in more detail than has been possible before, researchers in Seattle report. “We hope this method will improve our understanding of normal cell physiology and as well as of cell dynamics […]
April 14, 2020

Yale test of immunotherapy drug for advanced lung cancer shows promise

Lung cancer spreads to the brain in about one-quarter of patients with an advanced form of the disease. To date, radiation has been the only treatment option, but it comes with toxic side effects. Researchers at Yale Cancer Center (YCC) have found that the use of the checkpoint inhibitor pembrolizumab in […]
April 9, 2020

Autoimmunity may be rising in the United States

Autoimmunity, a condition in which the body’s immune system reacts with components of its own cells, appears to be increasing in the United States, according to scientists at the National Institutes of Health and their collaborators. In a study published in Arthritis and Rheumatology, the researchers found that the prevalence […]
April 9, 2020

Tiny Nanoparticles Offer Large Potential for Brain Cancer Treatment

For patients with malignant brain tumors, the prognosis remains dismal. With the most aggressive treatments available, patients are usually only expected to live about 14 months after diagnosis. This is because, chemotherapy, the most common form of treatment for cancer, is uniquely challenging for brain tumor patients. The delicate organ […]
April 8, 2020

Loss of Autophagy in Hematopoietic Cells Contributes to Osteoporosis

This open access paper is an example of one of the less well known connections between processes of aging. Loss of efficiency of the cellular maintenance processes of autophagy is a characteristic of cells in old tissues. Here, researchers note that this dysfunction in the hematopoietic cells responsible for creating blood and immune […]
April 8, 2020

Engineered Stem Cells Survive Longer and Improve Outcomes in a Heart Patch

In most cell therapies, the transplanted cells do not survive for long, or in large numbers. They produce beneficial effects, such as reduced inflammation or enhanced regeneration, via signaling that changes the behavior of native cell populations. Considerable effort is going into finding ways to make cells used in therapy survive for […]
April 8, 2020

PARP Inhibitor Drugs Can be “Tuned” for Better Killing of Tumor Cells

A prospective “PARP inhibitor” drug that has struggled to show effectiveness in clinical trials against cancers can be structurally modified to greatly increase its power to kill tumor cells, researchers from Penn Medicine report in Science. The team also showed that PARP inhibitor compounds can be “tuned” in the opposite […]
April 8, 2020

Genes sow seeds of neuropsychiatric diseases even before birth

From early prenatal development through childhood, the prefrontal cortex of the human brain undergoes an avalanche of developmental activity. In some cases, it also contains seeds of neuropsychiatric illnesses and conditions such as autism spectrum disorder and schizophrenia, according to a new genetic analysis led by researchers at Yale University […]
April 8, 2020

Celiac disease linked to increased mortality

People with celiac disease have increased risk of dying prematurely, despite increased awareness of the disease in recent years and better access to gluten-free food. This is according to a new study from Karolinska Institutet in Sweden and Columbia University in the U.S. published in the prestigious journal JAMA. Celiac […]
April 7, 2020

Physical force alone spurs gene expression, study reveals

Cells will ramp up gene expression in response to physical forces alone, a new study finds. Gene activation, the first step of protein production, starts less than one millisecond after a cell is stretched – hundreds of times faster than chemical signals can travel, the researchers report. The scientists tested […]
April 7, 2020

Probiotics could help people with autoimmune diseases

Millions of people around the world are suffering from autoimmune diseases. It is conditions when immune system mistakenly attacks body’s healthy cells. Think Multiple Sclerosis (MS), Lupus, and rheumatoid arthritis. Now scientists from Victoria University in Australia found that  a common probiotic could help people with autoimmune diseases by reducing […]
April 7, 2020

Human skin suppresses inflammation after exposure to ultraviolet radiation

A study led by an NIHR Manchester Biomedical Research Centre scientist has identified, for the first time, how the human skin suppresses inflammation after exposure to ultraviolet radiation (UVR). Dr. Nathan Hawkshaw is the lead author of a research paper published in Clinical & Translational Immunology, open access, peer-reviewed journal. […]
April 7, 2020

Alzheimer’s trial screening data links high amyloid levels with early stage disease

The first published data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) study supports the hypothesis that higher levels of the amyloid protein in the brain represent an early stage of Alzheimer’s disease. Results of an analysis of participant screening data for the study, published in JAMA Neurology, also […]
April 7, 2020

Protein implicated in dry eye and PTSD visualized at atomic level

Researchers have captured an atomic-level high-definition image of a protein and the small molecule that binds to it. Both have been implicated in conditions including dry eye and post-traumatic stress disorder (PTSD). Full understanding of their structures will hopefully lead to the development of an effective drug to regulate the […]
April 7, 2020

Blue Light? Orange Light? Tuning up sleep with tunable lighting

Lighting color and intensity affects sleep at nursing home. The science of lighting is about more than brightness, efficiency, and cost. Just ask anyone with seasonal affective disorder, or SAD, how gray skies and short days can affect their mood. It turns out that light—the right kind of light, at […]
April 7, 2020

Fighting cancer with slime chemistry and BNCT – Research video

Expectations are growing for Boron Neutron Capture Therapy (BNCT), a new cancer treatment, with few side effects, that combines thermal neutron irradiation and drug delivery. In BNCT, drugs are used to introduce boron specifically into cancer cells. The cancer cells are then irradiated, killing them with thermal neutrons. By targeting […]
April 7, 2020

Red wine compound could help you live a longer and healthier life

Consuming excess alcohol has always been associated with poor health. However, some scientists suggest that a small glass of wine per day can actually do a lot of good for you. Why? As this new study from UCL has noted it is all due to a dietary compound resveratrol, found […]
April 7, 2020

Can lobster really teach us how to live forever?

You know lobsters from TV documentaries, school biology books and restaurant menus. You may know that they can grow up to be pretty big and that they are delicious. You might also have seen a bizarre fact about them floating on the internet – lobsters do not age and are […]
April 6, 2020

Chilling concussed cells shows promise for full recovery

In the future, treating a concussion could be as simple as cooling the brain. That’s according to research conducted by the University of Wisconsin–Madison engineers, whose findings support the treatment approach at the cellular level. “There are currently no effective medical treatments for concussions and other types of traumatic brain […]
April 6, 2020

How understanding the dynamics of yeast prions can shed light on neurodegenerative diseases

Prions, a class of misfolded proteins, have a tendency to form infectious aggregates, causing deadly neurodegenerative diseases in humans (such as Alzheimer's). In a new study, scientists at Tokyo Institute of Technology (Tokyo Tech) and Kanazawa University use high-speed atomic force microscopy to uncover the structural and dynamic properties of […]