Related Science News – Page 35 – Innovita Research

Related Science News

May 26, 2021

Flickering Lights and Sound Could Be New Weapon Against Alzheimer’s

For the past few years, Annabelle Singer and her collaborators have been using flickering lights and sound to treat mouse models of Alzheimer’s disease, and they’ve seen some dramatic results. Now they have resulted from the first human feasibility study of the flicker treatment, and they’re promising. “We looked at safety, tolerance, and adherence, […]
May 26, 2021

Nasal spray could be used to treat Parkinson's disease

Parkinson’s disease is an incurable neurodegenerative condition, affecting millions of people in the world. It is one of the leading causes of age-related dementia as well as a very common cause of disability or death. Now scientists at the University of York are pushing to make a nasal spray treatment […]
May 25, 2021

People with familial longevity show better cognitive aging

If you come from a family where people routinely live well into old age, you will likely have better cognitive function (the ability to clearly think, learn and remember) than peers from families where people die younger. Researchers affiliated with the Long Life Family Study (LLFS) recently broadened that finding […]
May 25, 2021

Full-Genome CRISPR Screen Reveals Surprising Ways Neurons Survive Oxidative Stress

When a single gene in a cell is turned on or off, its resulting presence or absence can affect the function and survival of the cell. In a new study appearing in Nature Neuroscience, UCSF researchers have successfully catalogued this effect in the human neuron by separately toggling each of […]
May 25, 2021

Imaging project finds the machinery behind brain cells

Ultrahigh-resolution, high-speed imaging of fruit fly brains has allowed University of Oregon scientists to capture mechanical motions that stem cells use to make neurons, the cells that make up the brain. The motions coordinate cell division during differentiation, when some newly born cells become neurons. Differentiation is essential for building […]
May 25, 2021

Researchers intend to discover microbiome’s role in personalized nutrition

Personalized nutrition has emerged in recent years as a key potential solution to a variety of diseases that originate in the gut, and Nebraska scientists are mining microbiome data to determine how individuals’ digestive systems might respond to different nutritional approaches. Ultimately, these findings could help scientists and doctors recommend […]
May 25, 2021

Brain’s memory center stays active during ‘infantile amnesia’

One trait shared by all humans is that they don’t remember specific life episodes that occurred before the age of 3 or 4.  Many scientists have attributed this so-called “infantile amnesia” to a lack of development in the hippocampus, an area of the brain located in the temporal lobe that is […]
May 24, 2021

Whole Genome Sequencing of Supercentenarians in Search of Genetic Contributions to Longevity

Researchers here report on DNA sequencing carried out in a (necessarily small) number of supercentenarians (age 110 and over) and semi-supercentenarians (age 105 to 109), and identification of genetic variants associated with DNA repair and clonal hematopoiesis that are more common in these survivors to late old age. We should […]
May 24, 2021

Nerve signaling alerts the host to bacterial infection within hours

An exciting new way has been found in which the body senses a bacterial infection within 4 hours and uses nerve pathways to trigger an immune response in distant organs. The speed by which an infection can be identified, and how the defence mechanisms are triggered is critical to infection […]
May 23, 2021

Targeting Microglia in the Aging Brain

The progressive age-related dysfunction of microglia in the aging brain is implicated in the progression of neurodegenerative disease, as well as the increased inflammation and forms of pathology found in the brain tissue of older individuals. In mice, clearance of microglia can be efficiently achieved and leads to a rapid […]
May 23, 2021

The microenvironment of breast cancer in three dimensions

Cancerous tumors thrive on blood, extending their roots deep into the fabric of the tissue around them. They alter the genetics of surrounding cells and evolve to avoid the protective attacks of immune cells. Now, Penn State researchers have developed a way to study the relationship between solid, difficult-to-treat tumors and the […]
May 22, 2021

Towards Many Efforts to Produce Rejuvenation Therapies Based on Cellular Reprogramming

There is enthusiasm in the research community for in vivo cellular reprogramming as a path to treat aging. Reprogramming somatic cells to pluripotency recaptures some of the processes that take place in the developing embryo, and has been shown to restore youthful patterns of gene expression, leading to improved mitochondrial […]
May 22, 2021

How plants leave behind their parents’ genomic baggage

Passing down a healthy genome is a critical part of creating viable offspring. But what happens when you have harmful modifications in your genome that you don’t want to pass down? Baby plants have evolved a method to wipe the slate clean and reinstall only the modifications that they need to grow […]
May 22, 2021

Pioneering dementia scanner set to be rolled out across Wales

It comes after a successful pilot between Cardiff University’s Wales Research and Diagnostic PET Imaging Centre at the University Hospital of Wales, Aneurin Bevan University Health Board and the Royal College of Psychiatrists in Wales. From this week the technology will be available across all health boards – and it is hoped […]
May 22, 2021

Researchers grow mini-organs to study brain development and disease

“Organoids.” It’s a word that has a science-fiction sound to it, but, in fact, organoids are at the core of what scientist Jeff Wrana calls “revolutionizing biology.” That’s because organoids offer the promise of new treatments for a host of diseases and conditions, from inflammatory bowel disease to autism spectrum disorder. “An […]
May 22, 2021

Body chemistry can predict severity of depression after death of spouse

A new study from researchers at Rice University has found that bodily inflammation after the death of a spouse can predict future depression. “Inflammation and future depressive symptoms among recently bereaved spouses” will appear in the June 2021 edition of the journal Psychoneuroendocrinology. Lead author Lydia Wu, a Rice psychology […]
May 21, 2021

Getting to the Root of Alzheimer’s

Harvard Medical School researchers at Massachusetts General Hospital have discovered how amyloid-beta—the neurotoxin believed to be at the root of Alzheimer’s disease—forms in axons and related structures that connect neurons in the brain, where it causes the most damage. Their findings, published in Cell Reports, could serve as a guidepost for […]
May 21, 2021

New insights into hormone's action could help in battle against prostate cancer

Researchers at UVA Cancer Center have unveiled important new insights into how hormones known as androgens act on our cells – and the discovery could boost efforts to develop better treatments for prostate, ovarian and breast cancers. The findings shed light on how androgens interact with their receptors inside cells […]
May 21, 2021

New test will benefit children with asymptomatic Zika

The research team found they could detect heart abnormalities in infants and toddlers months or years after their exposure to the virus. A new device will let doctors monitor infants and toddlers who are asymptomatic with Zika after contracting the virus in utero from their mothers, according to a recently published report in the […]
May 21, 2021

Molecule enlists patient’s immune system to combat HIV

Antiretroviral therapy, the common approach in the treatment of HIV, halts replication of the virus and has saved the lives of millions of people. However, for patients, the drug cocktail becomes a lifetime necessity because they continue to harbour latent HIV in a small number of immune system cells. In […]
May 21, 2021

The New Credible Science of Longevity versus the Old Anti-Aging Snake Oil

The “anti-aging” marketplace has long been a pit of fraud, lies, hopes, and dreams, and blatantly so. Whatever the supplement sellers and cosmetics companies that dominate that industry have to say about the capabilities of their products is essentially nonsense, and this play-acting is accepted by the public as just […]
May 20, 2021

Team completes a large-scale study into the role of RNA maturation for organ development in mammals

Researchers from Russia and Germany have created a genome-wide atlas of developmental alternative splicing changes of seven organs in six mammal species and chicken. The research was published in the journal Nature Genetics. As the protein encoding RNA matures in eukaryotes, it gets spliced, with some parts cut out and […]
May 20, 2021

Engineering T cells to attack cancer broadly

Through T cell engineering, researchers at Virginia Commonwealth University Massey Cancer Center show that it’s possible to arrest tumor growth for a variety of cancers and squash the spread of cancer to other tissues. This research will be published in tomorrow’s print edition of Cancer Research. The paper builds on […]
May 20, 2021

Rogue antibodies wreak havoc in severe COVID-19 cases

The development of antibodies to the COVID-19 virus has been the great long-term hope of ending the pandemic. However, immune system turncoats are also major culprits in severe cases of COVID-19, Yale scientists report in the journal Nature. These autoantibodies target and react with a person’s tissues or organs similar to […]
May 20, 2021

Researchers get closer to gene therapy that would restore hearing for the congenitally deaf

Researchers at Oregon State University have found a key new piece of the puzzle in the quest to use gene therapy to enable people born deaf to hear. The work centres around a large gene responsible for an inner-ear protein, otoferlin. Mutations in otoferlin are linked to severe congenital hearing […]
May 20, 2021

Western diet may increase risk of gut inflammation, infection

Eating a Western diet impairs the immune system in the gut in ways that could increase the risk of infection and inflammatory bowel disease, according to a study from researchers at Washington University School of Medicine in St. Louis and Cleveland Clinic. The study, in mice and people, showed that […]
May 20, 2021

Eating habits change only slightly after gestational diabetes diagnosis, NIH study suggests

Pregnant women made only modest dietary changes after being diagnosed with gestational diabetes, according to a study by researchers at the National Institutes of Health. Women with gestational diabetes are generally advised to reduce their carbohydrate intake, and the women in the study did cut their daily intake of juice […]
May 20, 2021

New findings provide hope for treatment of multiple myeloma

Researchers at Karolinska Institutet have investigated the use of low dose venetoclax, an experimental drug, for the treatment of the heterogeneous cancer disease multiple myeloma in patients who had relapsed on standard therapies. The findings are published in the American Journal of Hematology and provide new hope for the treatment […]
May 20, 2021

Good results with online CBT for atopic eczema

The common skin disease atopic eczema (AE) impacts heavily on the life quality and general health of sufferers. Researchers at Karolinska Institutet have now evaluated its treatment with internet-delivered cognitive behavioural therapy (iCBT). The study suggests that patients feel better after iCBT compared with a control group who received only […]
May 20, 2021

New study shows flies mutant for schizophrenia-associated genes respond well to anti-psychotics

Scientists at Bristol have successfully treated flies displaying behavioural problems linked to newly discovered schizophrenia-associated genes in humans, using common antipsychotics. Schizophrenia is a severe long-term mental health condition that is historically poorly understood and treated. It is relatively common, affecting one to two per cent of the population, and […]