Related Science News – Page 36 – Innovita Research

Related Science News

February 15, 2019

How Breast Tissue Stiffening Promotes Breast Cancer Development

A study provides new insight into how the stiffening of breast tissue plays a role in breast cancer development. By examining how mammary cells respond in a stiffness-changing hydrogel, bioengineers at the University of California San Diego discovered that several pathways work together to promote the transformation of breast cells […]
February 15, 2019

‘Improbable Things Happen’

For some of us, they carry the bright blue of our grandfather’s eyes. For others they result in the characteristic cleft chin or the familial tendency toward color blindness. But in some families, the genetic mutations handed down from generation to generation aren’t as benign. And for one family in […]
February 15, 2019

Taking Sleep to Heart

Getting enough sleep is key to good health, and studies have shown that insufficient sleep increases the risk of serious problems, including cardiovascular disease. Now, Harvard Medical School researchers based at Massachusetts General Hospital have discovered one way that sleep protects against atherosclerosis, the buildup of arterial plaques. In their […]
February 15, 2019

With Age Comes Hearing Loss and a Greater Risk of Cognitive Decline

Hearing impairment is a common consequence of advancing age. Almost three-quarters of U.S. adults age 70 and older suffer from some degree of hearing loss. One unanswered question has been to what degree hearing impairment intersects with and influences age-related cognitive decline. In a new study, researchers at University of […]
February 15, 2019

Morning exercise improves brain health in older, overweight adults

An international research team led by The University of Western Australia and The Baker Institute in Melbourne has found a morning bout of exercise reduces the detrimental impact on the pattern of brain blood flow of prolonged sitting in older adults who are overweight or obese. Lead researcher Michael Wheeler, […]
February 15, 2019

Scientists catch heartbeat ‘molecular switch’ in action

Oxford University Radcliffe Department of Medicine researchers have developed a new method that uses a protein originally found in marine corals to visualise the flow of calcium that makes the heart beat.  In a paper published in the journal Circulation Research, they used this technique to uncover the effects of genetic […]
February 14, 2019

Stem Cells Provide Greater Insight into Rotator Cuff Disease

Rotator cuff tears are common injuries, and proper healing of the shoulder muscle is often difficult. “Chronic tears often result in fat accumulation within the rotator cuff muscles, resulting in negative clinical outcomes, including weakening and atrophy of the muscles,” says Manuel Schubert, M.D., resident in orthopaedic surgery at Michigan Medicine. […]
February 14, 2019

Hibernating hamsters could provide new clues to Alzheimer's disease

Syrian hamsters are golden-haired rodents often kept as house pets. Cold and darkness can cause the animals to hibernate for 3-4 days at a time, interspersed with short periods of activity. Surprisingly, the hibernation spurts of these cute, furry creatures could hold clues to better treatments for Alzheimer’s disease (AD), […]
February 14, 2019

Shared genetic marker offers new promise in targeting specific ovarian and lung cancers

Two new papers, published simultaneously in Nature Communications and led by researchers at McGill University, offer promise that a drug currently used to treat estrogen positive breast cancer may be effective in treating two different types of cancer, one rare and one common form. The breakthrough discovery launching this research came in […]
February 13, 2019

Gene Therapy Treatment Targets Rare Mutation Tied to Blindness

Eye troubles detected at infancy began to take their toll when Emma Kate Roden started walking. The toddler would often bump into things because of poor eyesight. Now age 7, a rare genetic condition has continued to eat away at her vision. She can’t see after dark, so there are […]
February 13, 2019

3 Ways Genetic Counselors Provide Clarity on Eye Disease

The specialists can review an individual’s DNA following a doctor’s suspicion of retinitis pigmentosa, Stargardt disease or cone-rod dystrophy, among other vision-related conditions. The goal: to identify genetic mutations and associated inheritance patterns related to the disorder. “We consider genetic testing to be an integral part of making a diagnosis in […]
February 13, 2019

Circular RNA Holds Promise as Cancer Biomarker

As new technology allows researchers to plunge deeper into the genome and exome, a new class of RNA called circRNA, or circular RNA, may play an intriguing role. Researchers at the University of Michigan Rogel Cancer Center have cataloged circular RNA in multiple cancers. Their initial research suggests these stable structures could […]
February 13, 2019

Less anesthesia during surgery doesn’t prevent post-op delirium, but reduces death risk

Many older adults who have major surgery experience postoperative delirium in the days after their operations. Previous research has suggested that closely monitoring the brain during surgery and making adjustments to protect the brain from too much anesthesia could reduce risk of postoperative delirium. But in a new study of […]
February 13, 2019

Women’s brains appear three years younger than men’s

Time wears differently on women’s and men’s brains. While the brain tends to shrink with age, men’s diminish faster than women’s. The brain’s metabolism slows as people grow older, and this, too, may differ between men and women. A new study from Washington University School of Medicine in St. Louis […]
February 12, 2019

Study of Arctic fishes reveals the birth of a gene – from ‘junk’

Though separated by a world of ocean, and unrelated to each other, two fish groups – one in the Arctic, the other in the Antarctic – share a surprising survival strategy: They both have evolved the ability to produce the same special brand of antifreeze protein in their tissues. A […]
February 12, 2019

Discovery may bolster chemotherapy potency while protecting the heart from side-effects

Researchers from the University of Alberta may have found a way to make chemotherapy more effective at treating cancer while blocking its harmful side-effects on the heart. While chemotherapy can be an effective treatment for cancer, the aggressive attack on cancer cells often cause damage to other cells throughout the […]
February 12, 2019

Study Links Adult Fibromyalgia to Childhood Sexual Abuse

A new Tel Aviv University study finds that fibromyalgia syndrome — a chronic condition characterized by widespread pain, fatigue and cognitive difficulties — may be a consequence of post-traumatic physical and psychological distress associated with childhood sexual abuse. The research suggests that survivors of childhood sexual abuse who develop fibromyalgia may be […]
February 12, 2019

Functional Insulin-Producing Cells Grown In Lab

UC San Francisco researchers have for the first time transformed human stem cells into mature insulin-producing cells, a major breakthrough in the effort to develop a cure for type 1 (T1) diabetes. Replacing these cells, which are lost in patients with T1 diabetes, has long been a dream of regenerative […]
February 12, 2019

Scientists seeking to regrow kidneys make promising discovery

Scientists seeking to regrow damaged kidneys have discovered that blocked kidneys in newborns have a remarkable ability to repair themselves after the obstruction is removed. The finding offers insights into how that happens and could eventually help doctors regenerate kidneys in adults. The new research, from the University of Virginia […]
February 12, 2019

HIV drug could treat Alzheimer’s, age-associated disorders

A new study found that an HIV drug significantly reduces age-related inflammation and other signs of aging in mice. “This holds promise for treating age-associated disorders including Alzheimer’s,” said John Sedivy, professor of medical science and biology at Brown University. “And not just Alzheimer’s but many other diseases: Type 2 […]
February 12, 2019

Brain blood flow finding gives hope for Alzheimer’s therapy

You know that dizzy feeling you get when, after lying down for an extended period, you stand up a little too quickly? That feeling is caused by a sudden reduction of blood flow to the brain, a reduction of around 30 percent. Now imagine living every minute of every day […]
February 12, 2019

Brain does not forget amputated limbs even after several decades

Human body is very adaptable to various changes that occur during your lifetime. You notice that when some functions of your body become impaired. For example, those who lose limbs learn o get around without them very quickly. Now scientists from UCL and the University of Oxford found that detailed […]
February 11, 2019

Cancer cells’ plasticity makes them harder to stop

When metastatic cancer cells need to avoid a threat, they simply reprogram themselves. Rice University scientists are beginning to get a handle on how they survive hostile environments. Members of Rice’s Center for Theoretical Biological Physics (CTBP) and cancer metabolism researchers at Baylor College of Medicine have created a basic framework of […]
February 8, 2019

Drug target identified for chemotherapy-resistant ovarian, breast cancer

People who inherit a faulty copy of the so-called “breast cancer genes” BRCA1 and BRCA2 are at high risk of cancer. About 10 percent of breast cancer cases and 15 percent of ovarian cancers can be traced back to a flaw in one of these genes. A class of drugs known as PARP inhibitors […]
February 8, 2019

Study links psoriasis treatment and improvement in heart artery disease

Researchers have found that treating psoriasis, a chronic inflammatory skin disease, with biologic drugs that target immune system activity can reduce the early plaque buildup that clogs arteries, restricts blood flow, and leads to heart attacks and stroke. The findings highlight how immunotherapies that treat inflammatory conditions might play a […]
February 7, 2019

Anti-Rejection Drug Could be Repurposed to Treat Cancer

Research from the University of Pittsburgh School of Medicine in animal models and patient tissues has identified a new molecular pathway in the liver that suggests a commonly used anti-rejection medication could be repurposed to treat certain liver cancers. “What we’ve found is that liver cancers with a specific mutation in the […]
February 7, 2019

Measuring stress around cells

Tissues and organs in the human body are shaped through forces generated by cells, that push and pull, to “sculpt” biological structures. Thanks to a new tool developed at McGill University, scientists will now be able to watch, and map these forces. Christopher Moraes, an assistant professor in McGill’s Department […]
February 6, 2019

How Men Continually Produce Sperm — and How that Discovery Could Help Treat Infertility

The production of sperm — otherwise known as spermatogenesis — generates more than 1,000 sperm per second in normal males. This productivity comes, in part, from a special cell type called the spermatogonial stem cell. The staying power of this stem cell has allowed many celebrities, including Robert DeNiro and […]
February 6, 2019

The Hitchhiker’s Guide to Defeating Glioblastoma

MicroRNAs can weaken cancer cells in advance of standard therapy in preclinical models, study shows. In the quest for new cancer therapies, microRNAs—tiny strings of nucleotides churned out inside cells—have been a source of both excitement and disappointment. While preclinical studies have found that microRNAs play an important role in […]
February 6, 2019

Some gut cells slow down metabolism, accelerate cardiovascular disease

Researchers have discovered how specific cells in the guts of mice slow down metabolism and eventually contribute to obesity, diabetes, hypertension and atherosclerosis. The findings, scientists say, could have important implications for the prevention and treatment of these kinds of metabolic diseases in humans. The study was funded by the […]