Related Science News – Page 160 – Innovita Research

Related Science News

July 14, 2020

NIH researchers reframe dog-to-human aging comparisons

One of the most common misconceptions is that one human year equals seven dog years in terms of aging. However, this equivalency is misleading and has been consistently dismissed by veterinarians. A recent study, published in the journal Cell Systems(link is external), lays out a new framework for comparing dog-to-human aging. In […]
July 14, 2020

Fertility decline in ageing fruit flies is about ‘more than just sperm’

Research by the universities of Liverpool and Oxford reveals new insight into age-related fertility decline in male fruit flies. Infertility is one of the most striking effects of ageing. The impact of ageing on females’ fertility is more severe and much better understood, but it also affects males. Male reproductive […]
July 14, 2020

Living close to natural green space benefits gut bacteria of urban, formula-fed infants

First study of its kind shows formula-fed babies’ gut microbiomes more like those of breastfed babies when they live near natural environments. Living close to natural green space can mitigate some of the changes in infant gut bacteria associated with formula feeding, according to new research published in the journal Environment International. “Not […]
July 14, 2020

New database aims to make Alzheimer's diagnosis easier and earlier

Volunteers can add data with a five-minute online session. Do you get nervous when you can’t think of a word? Chances are it’s a momentary lapse, but problems with language are one of the symptoms that can indicate a neurodegenerative disorder like Alzheimer’s disease. Unfortunately, diagnosing these conditions requires scoring […]
July 14, 2020

Sensory Neurons Outside the Brain Drive Autistic Social Behaviors, Penn Study Suggests

A new study from Penn Medicine lends further evidence that the social behaviors tied to autism spectrum disorders (ASD) emerge from the abnormal function of sensory neurons outside the brain. It’s an important finding, published in the journal Cell Reports because peripheral sensory systems—which determine how we perceive the environment around us […]
July 14, 2020

To Let Neurons Talk, Immune Cells Clear Paths Through Brain’s ‘Scaffolding’

To make new memories, our brain cells first must find one another. Small protrusions that bud out from the ends of neurons’ long, branching tentacles dock neurons together so they can talk. These ports of cellular chatter – called synapses, and found in the trillions throughout the brain – allow […]
July 14, 2020

New Model of Breast Cancer’s Causes Developed by UCSF-led Team

A new model of the causes of breast cancer, created by a team led by researchers at UC San Francisco, Genentech and Stanford University, is designed to capture the complex interrelationships between dozens of primary and secondary breast cancer causes and stimulate further research. Breast cancer is the most common […]
July 14, 2020

Largest-Ever Study of Prostate Cancer Genomics in Black Men IDs Potential Targets for Precision Therapies

Black men in the United States are known to suffer disproportionately from prostate cancer, but few studies have investigated whether genetic differences in prostate tumors could have anything to do with these health disparities. Now, in the largest study of its kind to date, researchers from Boston University School of […]
July 14, 2020

Brain Benefits of Exercise Can Be Gained with a Single Protein

A little-studied liver protein may be responsible for the well-known benefits of exercise on the aging brain, according to a new study in mice by scientists in the UC San Francisco Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research. The findings could lead to new therapies to […]
July 14, 2020

New molecular tool precisely edits mitochondrial DNA

UW microbiologists discovered a bacterial toxin that, when engineered, is a key part of a gene editor that can make single-base changes in human mitochondria. The genome in mitochondria — the cell’s energy-producing organelles — is involved in disease and key biological functions, and the ability to precisely alter this […]
July 13, 2020

Dissecting fruit flies’ response to life-extension diet

Changes in a few small molecules involved in a cell’s metabolism seem to indicate whether a restricted “life extension” diet will actually extend, shorten, or have no effect on lifespan, a study of fruit flies has found. The findings suggest that analyzing the level of small molecules in cells, an […]
July 13, 2020

Yale, Baylor create detailed atlas of cellular change in lungs with fibrosis

A research team from Yale and Baylor College of Medicine has completed the largest single-cell analysis to date of lungs affected by Idiopathic Pulmonary Fibrosis (IPF), revealing how cells change in response to the disease and identifying previously unknown cell types. The findings, published in the issue of Science Advances, deepen […]
July 11, 2020

Brd2 Inhibition as an Approach to Slow Aging

There are innumerable studies showing small gains in mouse life span. Most cannot be reproduced, particularly the older ones, those that took place before it was common knowledge in the research community that one has to very aggressively control for accidental calorie restriction. If an intervention makes mice eat less, […]
July 10, 2020

The Aging Gut Microbiome Produces More Trimethylamine, Harming Arterial Function

In recent years academic interest has grown in the study of the gut microbiome. Researchers are making inroads into understanding the considerable influence of these microbial populations over the progression of health and aging. The gut microbiome may be as influential as physical activity in these matters. The balance of […]
July 10, 2020

Zika infection after birth shown to have long term brain and behavior issues in animals

Emory University researchers have shown that Zika virus infection soon after birth leads to long-term brain and behavior problems, including persistent socioemotional, cognitive and motor deficits, as well as abnormalities in brain structure and function. This study is one of the first to shed light on the potential long-term effects […]
July 10, 2020

Antibodies against lipid gives protection against rheumatic systemic disease

A novel study from the Institute of Environmental Medicine at Karolinska Institutet indicates that antibodies against a small lipid entity, phosphorylcholine (PC), can be associated with protection in inflammatory systemic diseases, including SLE and Sjögren´s syndrome. The results support evidence for a potential treatment by providing antibodies (anti-PC) to patients […]
July 9, 2020

Ex Vivo Mitochondrial Transfer as a Way to Improve Stem Cell Therapy Outcomes

A sizable portion of the variable efficacy of first generation stem cell therapies as presently practiced may be due to a poor quality of cells following expansion in culture. Regardless of quality, near all such cells die shortly after transplantation. Few clinics and few approaches to cell therapy lead to […]
July 9, 2020

Ageing research: Low levels of the stress hormone cortisol contribute to ageing

Why do we age? What exactly happens in the body? And: Can something be done about it? These are questions that have occupied science since time immemorial. The pharmacists Alexandra K. Kiemer and Jessica Hoppstädter from the Saarland University have not found a philosophical stone. But: they have uncovered processes […]
July 9, 2020

How long should people work? Workers in UK don't stay healthy for that long

Everyone is aging – time is not choosing its victims. You start of young and beautiful and energized, but eventually your body and mind start falling behind and you have to retire. But when would be an appropriate time to retire? Scientists from the Newcastle University say that 50 year […]
July 8, 2020

Aichi Cancer Center and NEC Launch Joint Research on Fundamental Study Aimed at Advanced Cancer Immunotherapy

Aichi Cancer Center(1) and NEC Corporation (NEC; 6701) today announced the launch of fundamental research aiming to realize the promise of advanced personalized cancer immunotherapy by improving the performance of NEC's neoantigen prediction system and developing predictive biomarkers for patient stratification through the fusion of AI and experimental immunology. This […]
July 8, 2020

Black raspberries show promise for reducing skin inflammation

Eating black raspberries might reduce inflammation associated with skin allergies, a new study indicates. In a study done with mice and published earlier in the journal Nutrients, researchers found that a diet high in black raspberries reduced inflammation from contact hypersensitivity – a condition that causes redness and inflammation in […]
July 7, 2020

Brain imaging can predict Alzheimer’s-related memory loss

Researchers at Karolinska Institutet have imaged tau protein in the brains of living patients with Alzheimer’s disease. The amount and spread of tau proved a predictor of future memory loss. Brain imaging for measuring tau can be useful both for improving diagnosis and for developing more effective treatments, say the […]
July 7, 2020

Team develops new approach to treat certain neurological diseases

Research produces dramatic results in laboratory studies involving fatal myelin disease that strikes children. A team led by Case Western Reserve University medical researchers has developed a potential treatment method for Pelizaeus-Merzbacher disease (PMD), a fatal neurological disorder that produces severe movement, motor and cognitive dysfunction in children. It results […]
July 6, 2020

Targeting Cellular Senescence as an Intervention in Aging

Senolytic drugs that destroy senescent cells, and later on, other senotherapies that either prevent senescence or block the senescence-associated secretory phenotype (SASP), are going to be very important in the treatment of aging. Senescent cells accumulate with age and are highly damaging to tissues. Via the SASP, even comparatively small […]
July 6, 2020

Aging Impacts Progenitor Cells in the Thymus

The age-related decline of the immune system has several causes, but the involution of the thymus is an important one. The thymus is responsible for the production of mature T cells of the adaptive immune system, but the organ atrophies with age. The supply of new T cells falls off […]
July 6, 2020

Far Too Little Consideration is Given to the Failure of the Immune System in the Old

There is no situation so terrible that it will not be silently accepted as set in stone, only given that it has lasted for long enough to become routine. So it is with aging, and all of the pain, suffering, and death that accompanies it. The present furor surrounding COVID-19 […]
July 6, 2020

Receptor makes mice strong and slim

Increasing abdominal girth and shrinking muscles are two common side effects of aging. Researchers at the University of Bonn have discovered a receptor in mice that regulates both effects. Experiments with human cell cultures suggest that the corresponding signaling pathways might also exist in humans. The study, which also involved […]
July 6, 2020

Poor sleep in infancy is related to mental disorders in adolescence

Some studies take months to complete, some take years and some can even take decades. When scientists from the University of Birmingham set out to research what kind of effects infant sleep problems have for their adult life, they knew that this study will take a long time. And it […]
July 3, 2020

Secrets of naked mole-rat cancer resistance unearthed

Naked mole-rats can live for an incredibly long time and have an exceptional resistance to cancer thanks to unique conditions in their bodies that stop cancer cells multiplying, according to new research. Understanding how these remarkable animals are almost completely immune to cancer could improve our understanding of the early stages […]
July 3, 2020

How Old Is Your Dog in Human Years? Scientists Develop Better Method than ‘Multiply by 7’

By mapping molecular changes in the genome over time, UC San Diego researchers developed a formula to more accurately compare dog age to human age—a tool that could also help them evaluate how well anti-aging products work. If there’s one myth that has persisted through the years without much evidence, […]