Related Science News – Page 2 – Innovita Research

Related Science News

February 27, 2021

Gene critical to immune cell development identified

Much of the three-dimensional architecture of the genome in antibody-producing immune cells is dependent on a gene called SMC3. When this gene is not working properly it can lead to improper immune cell development and to cancer, by disrupting how DNA is structured inside the cell nucleus, according to a […]
February 27, 2021

Genetics May Play Role in Determining Immunity to COVID-19

Neutralizing antibodies develop within two weeks of a SARS-CoV-2 infection, but their durability and intensity can vary by individual, prompting concerns about the prospects of long-lasting immunity and efficacy of COVID-19 vaccines. In a PLOS ONE paper researchers at University of California San Diego School of Medicine report that individual immune […]
February 27, 2021

First-in-Human Clinical Trial to Assess Gene Therapy for Alzheimer’s Disease

UC San Diego researchers will inject harmless virus carrying a restorative gene into participants’ brains, where earlier animal studies suggest it may slow, prevent or reverse progression of the neurological disorder. Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to […]
February 27, 2021

Last-Itch Effort: Fighting the Bacteria That Exacerbate Eczema with Bacteria

In a new study out of University of California San Diego School of Medicine, researchers have identified a universal strain of bacteria derived from healthy human skin that can treat the most common type of eczema, also known as atopic dermatitis. In the paper published in Nature Medicine, the research […]
February 27, 2021

Genetic Tool Improves Estimation of Prostate Cancer Risk in Diverse Ethnic/Racial Groups

Building upon previous research, an international team led by scientists at University of California San Diego School of Medicine, has validated a more inclusive and comprehensive genetic tool for predicting age of onset of aggressive prostate cancer, a disease that killed more than 33,000 American men in 2020. Reporting in […]
February 27, 2021

A new way beckons to treat severe obesity

New research by a prestigious Université de Montréal researcher could pave the way for the treatment of early morbid familial obesity, a disease that affects four to six per cent of people suffering from early severe obesity. Co-authored by Michel Bouvier and Patricia René of UdeM’s Institute for Research in […]
February 27, 2021

Bioinformatics tool accurately tracks synthetic DNA

Tracking the origin of synthetic genetic code has never been simple, but it can be done through bioinformatic or, increasingly, deep learning computational approaches. Though the latter gets the lion’s share of attention, new research by computer scientist Todd Treangen of Rice University’s Brown School of Engineering is focused on whether sequence alignment and pan-genome-based methods can outperform recent […]
February 27, 2021

Weill Neurohub joins with Genentech, Roche to advance neuroscience research

The University of California, San Francisco (UCSF) and UC Berkeley announced a long-term research partnership with Genentech, a member of the Roche Group, and its parent company, Roche Holding AG, to speed the development of new therapeutics for debilitating brain diseases and disorders of the central nervous system (CNS), such […]
February 26, 2021

Researchers take an early step toward leukemia drug therapy

A McMaster stem cell research team has made an important early step in developing a new class of therapeutics for patients with a deadly blood cancer. The team has discovered that for acute myeloid leukemia (AML) patients, there is a dopamine receptor pathway that becomes abnormally activated in the cancer […]
February 26, 2021

Scientists capture the choreography of a developing brain

The formation of a brain is one of nature’s most staggeringly complex accomplishments. The intricate intermingling of neurons and the labyrinth of connections also make it a particularly difficult feat for scientists to study. Now, Yale researchers and collaborators have devised a strategy that allows them to see this previously […]
February 26, 2021

New strategy blocks chronic lung disease in mice

Inflammatory lung diseases such as asthma, COPD and, most recently, COVID-19, have proven difficult to treat. Current therapies reduce symptoms and do little to stop such diseases from continuing to damage the lungs. Much research into treating chronic inflammatory diseases has focused on blocking chemicals called cytokines, which trigger cascades […]
February 26, 2021

New experiences enhance learning by resetting key brain circuit

A study of spatial learning in mice shows that exposure to new experiences dampens established representations in the brain’s hippocampus and prefrontal cortex, allowing the mice to learn new navigation strategies. The study, published in Nature, was supported by the National Institutes of Health. “The ability to flexibly learn in new […]
February 26, 2021

NIH study: people with SARS-CoV-2 antibodies may have a low risk of future infection

People who have had evidence of a prior infection with SARS-CoV-2, the virus that causes COVID-19, appear to be well protected against being reinfected with the virus, at least for a few months, according to a newly published study from the National Cancer Institute (NCI). This finding may explain why reinfection appears […]
February 26, 2021

Joining Forces to Cure Glaucoma

First-time analyses of glaucoma across multiple ancestries find new genetic variants. In the largest genome-wide association study of glaucoma to date, which compared the genes of 34,179 people with the disease to 349,321 control participants, an international consortium of researchers identified 44 new gene loci and confirmed 83 previously reported […]
February 26, 2021

Treating rheumatoid arthritis with micromotors

Rheumatoid arthritis is a chronic inflammatory disorder marked by joint pain, swelling and damage. Although medications, such as steroids, anti-inflammatory drugs and immunosuppressants, can help slow joint destruction and relieve pain, they have side effects and aren’t completely successful. Now, researchers reporting in ACS’ Nano Letters have developed magnesium-based micromotors propelled by […]
February 26, 2021

AI researchers ask: What’s going on inside the black box?

Cold Spring Harbor Laboratory (CSHL) Assistant Professor Peter Koo and collaborator Matt Ploenzke reported a way to train machines to predict the function of DNA sequences. They used “neural nets,” a type of artificial intelligence (AI) typically used to classify images. Teaching the neural net to predict the function of short stretches […]
February 26, 2021

Tweaking corn kernels with CRISPR

Corn—or maize—has changed over thousands of years from weedy plants that make ears with less than a dozen kernels to the cobs packed with hundreds of juicy kernels that we see on farms today. Powerful DNA-editing techniques such as CRISPR can speed up that process. Cold Spring Harbor Laboratory (CSHL) […]
February 26, 2021

Pancreatic cancer clinical trial program to target genome and scar tissue

A national clinical trial program will test promising new targeted therapy for pancreatic cancer, one of the deadliest forms of cancers of which more than 3000 cases are diagnosed annually in Australia alone. The clinical trial program (MoST–P), led by researchers and clinicians at UNSW Sydney and the Garvan Institute […]
February 25, 2021

Common anti-depressant may be first-ever treatment for osteoarthritis

A disease of the joints, osteoarthritis affects more than 30 million adults and is the fifth-leading cause of disability in the United States. In a new study, scientists have discovered the cellular pathway that leads to osteoarthritis and have identified a commonly used anti-depressant — paroxetine — that inhibits this […]
February 25, 2021

Long-term stress linked to increased risk of heart attack

Can long-term stress lead to heart attacks? Most people would probably answer in the affirmative, but the scientific evidence of this is scarce. A new study reveals that the levels of the stress hormone cortisol were increased in the months preceding a heart attack. The results suggest that long-term stress […]
February 25, 2021

Basic cell health systems wear down in Huntington’s disease, analysis shows

A new computational approach for analyzing complex datasets shows that as disease progresses, neurons and astrocytes lose the ability to maintain homeostasis. Using an innovative computational approach to analyze vast brain cell gene expression datasets, researchers at MIT and Sorbonne Université have found that Huntington’s disease may progress to advanced […]
February 25, 2021

Critical step forward for radiotherapy with a new method to treat cancer

A new research development from The University of Manchester and The Christie NHS Foundation Trust has shown progress for developing a potential new cancer treatment using high energy electron beams. The collaborative research team have published their findings in Nature’s journal, Scientific Reports, and demonstrated that Very High Energy Electron (VHEE) beams can have […]
February 25, 2021

Using predictive biomarkers could improve success rate of new cancer drugs

In recent decades, researchers have made big advances in developing new cancer medicines such as Herceptin, the targeted drug to treat women diagnosed with HER2-positive breast cancer. Yet, despite these successes, cancer remains the second leading cause of death after heart disease and nearly 90 per cent of all cancer drugs entering […]
February 25, 2021

"Good bacteria" in breast milk changes over time

The cocktail of beneficial bacteria passed from mother to infant through breast milk changes significantly over time and could act like a daily booster shot for infant immunity and metabolism. The research, conducted by scientists from Montreal and Guatemala and published in Frontiers in Microbiology, has important implications for infant development […]
February 25, 2021

From out of the blue comes a better bladder-cancer detector

Decades ago, blue lights helped shoppers scope out sales. Today they’re helping urologists scope out cells, specifically those of non-muscle-invasive bladder cancer. UW Medicine urologists with the Seattle Cancer Care Alliance possess a mechanism that makes the tumors glow bright pink. All the better to see them. “Seventy percent of bladder […]
February 25, 2021

Penn Scientists Discover Microbial Transplants Require Key T Cells for Success

Scientists have known for more than a decade that “good bacteria” from healthy intestines can treat and ward off potentially deadly intestinal infections by Clostridium difficile bacteria. Now researchers at the Perelman School of Medicine at the University of Pennsylvania have discovered that immune cells called Treg cells are crucial for the success […]
February 25, 2021

Fat cells may influence how the body reacts to heart failure, study shows

University of Alberta researchers have found that limiting the amount of fat the body releases into the bloodstream from fat cells during heart failure could help improve outcomes for patients. In a recent study published in the American Journal of Physiology, Jason Dyck, professor of paediatrics in the Faculty of Medicine & Dentistry and director […]
February 25, 2021

Seeing schizophrenia: X-rays shed light on neural differences, point toward treatment

An international research team used the ultrabright X-rays of the Advanced Photon Source to examine neurons in the brains of schizophrenia patients. What they learned may help neurologists treat this harmful brain disorder. Schizophrenia, a chronic, neurological brain disorder, affects millions of people around the world. It causes a fracture […]
February 25, 2021

Reactivating Aging Stem Cells in the Brain

As people get older, their neural stem cells lose the ability to proliferate and produce new neurons, leading to a decline in memory function. Researchers at the University of Zurich have now discovered a mechanism linked to stem cell aging – and how the production of neurons can be reactivated. […]
February 24, 2021

Challenge: Device to Address Calcified Coronary Arteries

NineSigma, representing a global 500 medical device company, invites proposals for technologies that can alleviate the deleterious effects of calcified coronary arteries in a manner that is both easier and safer than traditional angioplasty or atherectomy procedures. The goal of this RFP is to identify technologies, beyond those that are traditionally […]