Related Science News

December 29, 2020

The Body is a Network: Cell Signaling in Age-Slowing Interventions

The authors of this open access papers discuss the prominent role of cell signaling in the better known classes of intervention that have been shown to slow aging in worms, flies, and mice. The body is a network in which cells in one tissue influence the behavior of cells in […]
December 29, 2020

Study links metabolic syndrome to higher cardiovascular risk in patients with psoriasis

Psoriasis, a chronic inflammatory skin disease, has long been known to increase the risk of cardiovascular disease, which includes heart attack and stroke. Now, researchers have identified a key culprit: the presence of metabolic syndrome (MetSyn), a condition that includes obesity, diabetes, high cholesterol, and hypertension, and is highly prevalent […]
December 29, 2020

AI-powered microscope could check cancer margins in minutes

When surgeons remove cancer, one of the first questions is, “Did they get it all?” Researchers from Rice University and the University of Texas MD Anderson Cancer Center have created a new microscope that can quickly and inexpensively image large tissue sections, potentially during surgery, to find the answer. The […]
December 28, 2020

Blood Pressure Drug may be Key to Increasing Lifespan, New Study Shows

Metolazone, a drug used to treat hypertension, activates a mitochondrial stress response that prolongs lifespan in the roundworm Caenorhabditis elegans A stress response of mitochondria, the part of our cells that produce energy to power bodily functions, is important to a longer life. A team of scientists from Osaka City […]
December 28, 2020

Light flips genetic switch in bacteria inside transparent worms

Baylor College of Medicine researcher Meng Wang had already shown that bacteria that make a metabolite called colanic acid (CA) could extend the lifespan of worms in her lab by as much as 50%, but her collaboration with Rice University synthetic biologist Jeffrey Tabor is providing tools to answer the bigger question of how […]
December 28, 2020

High levels of dementia found in the Torres Strait

James Cook University’s Professor Edward Strivens and Associate Professor Sarah Russell from JCU’s Healthy Ageing Research Team have found were part of a group that examined 276 Torres Strait residents aged between 45 and 93. The study took in all 18 island and 5 mainland communities in the Torres Strait […]
December 27, 2020

Artificial intelligence may diagnose the leading cause of blindness much earlier

Artificial intelligence is able to analyze vast amounts of information very quickly and efficiently. And, therefore, unsurprisingly it is very useful in medicine. Scientists from UCL and the Western Eye Hospital have now developed a new eye test, which takes advantage of AI technology to predict wet age-related macular degeneration […]
December 27, 2020

Testosterone therapy may help preventing type 2 diabetes

Type 2 diabetes is oftentimes called a lifestyle disease, because it is associated with obesity, poor levels of physical activity and a terrible diet. It can be prevented through lifestyle changes, but what are other options? A team of scientists led by the University of Adelaide conducted a 2 year […]
December 27, 2020

Scientists discover how our brains track where we and others go

For the first time, scientists have recorded how our brains navigate physical space and keep track of others’ location. Researchers used a special backpack to wirelessly monitor the brain waves of epilepsy patients as each one walked around an empty room hunting for a hidden, two-foot spot. In an article […]
December 27, 2020

Scientists at TAU develop new gene therapy for deafness

A new study from Tel Aviv University (TAU) presents an innovative treatment for deafness, based on the delivery of genetic material into the cells of the inner ear. The genetic material “replaces” the genetic defect and enables the cells to continue functioning normally. The scientists were able to prevent the gradual deterioration […]
December 26, 2020

Ketamine: New use for an old drug

Researchers at three Canadian universities find the key to unlocking the antidepressant effect of ketamine in the brain. A group of proteins called 4E-BPs involved in memory formation are key to unlocking the antidepressant effect of ketamine in the brain, according to a new study by researchers from three Canadian […]
December 26, 2020

UCSF and BridgeBio Pharma to Accelerate Therapies for Genetic Diseases

UC San Francisco and BridgeBio Pharma, Inc. (NASDAQ: BBIO) today announced a partnership to drive the advancement of academic innovations in genetically driven diseases into potential therapeutics for patients. “The BridgeBio team is developing close relationships with our investigators at UCSF with the mission of bringing potential therapies into the […]
December 26, 2020

Decoding our immune response is nothing but a genetic ‘turn off’

How genes get ‘switched on’ has fascinated scientists for decades, but equally important questions about how they are ‘turned off’ have been largely overlooked. As the messengers carrying instructions from DNA for the creation of proteins, the formation and decay of cellular RNAs is critical to maintaining cell stability and […]
December 25, 2020

Spatial maps give new view of gut microbiome

What microbes are in your gut, and where? Cornell researchers developed an imaging tool to create intricate spatial maps of the locations and identities of hundreds of different microbial species, such as those that make up the gut microbiome. The tool will help scientists understand how complex communities of microorganisms […]
December 25, 2020

Sex peptide causes female fruit fly’s gut to grow

Scientists have known that females of many species eat more to meet the demands of reproduction, and that females undergo widespread physiological and behavioral changes after mating. The mechanisms of these changes, however, are not well understood. A new study of the common fruit fly (Drosophila melanogaster) has identified a […]
December 25, 2020

What social distancing does to a brain

Have you recently wondered how social-distancing and self-isolation may be affecting your brain? An international research team led by Erin Schuman from the Max Planck Institute for Brain Research discovered a brain molecule that functions as a “thermometer” for the presence of others in an animal’s environment. Zebrafish “feel” the […]
December 25, 2020

Charting the developing brain

How can you build neuronal networks that are more complex than anything known today? Researchers at the Max Planck Institute for Brain Research in Frankfurt, Germany, have mapped the development of inhibitory neuronal circuitry and report the discovery of distinct circuit formation principles. Their findings enable scientists to monitor the […]
December 25, 2020

Embryonic development in a Petri dish

By growing mouse stem cells in a special gel, a Berlin research team succeeded to grow structures similar to parts of an embryo. The trunk-like structures develop the precursors for neural, bone, cartilage and muscle tissues from cellular clumps within five days. This could allow the investigation of the effects […]
December 25, 2020

New drug inhibits the growth of cancer cells

A newly developed compound starves cancer cells by attacking their “power plants” – the so-called mitochondria. The new compound prevents the genetic information within mitochondria from being read. Researchers from the Max Planck Institute for Biology of Ageing in Cologne, the Karolinska Institute in Stockholm and the University of Gothenburg […]
December 25, 2020

Cholesterol recycling supports myelin repair

As known from diseases such as arteriosclerosis, cholesterol deposits along blood vessels can be harmful. Similar problems occur in neurological diseases such as multiple sclerosis. Here, defects occur in the regeneration of cholesterol-rich myelin sheaths. The normal recycling of cholesterol from defective myelin sheaths by phagocytes is impaired. This leads […]
December 25, 2020

Lab-Grown Human Brain Organoids Mimic an Autism Spectrum Disorder, Help Test Treatments

Most autism spectrum disorders have a complex, multifactorial genetic component, making it difficult to find specific treatments. Rett syndrome is an exception. Babies born with this form of the disorder have mutations specifically in the MECP2 gene, causing a severe impairment in brain development that primarily affects females. Yet there is still […]
December 25, 2020

Researchers Discover Clue to How to Protect Neurons and Encourage Their Growth

Many neurodegenerative conditions, from glaucoma to Alzheimer’s disease, are characterized by injury to axons — the long, slender projections that conduct electrical impulses from one nerve cell to another, facilitating cellular communications. Injury to axons often leads to neuronal impairment and cell death. Researchers know that inhibiting an enzyme called […]
December 25, 2020

Pregnant women in third trimester unlikely to pass SARS-CoV-2 infection to newborns

Pregnant women who are infected with SARS-CoV-2, the virus that causes COVID-19, during the third trimester are unlikely to pass the infection to their newborns, suggests a study funded by the National Institutes of Health. The study followed 127 pregnant women who were admitted to Boston hospitals during the spring […]
December 25, 2020

New research highlights the importance of the thymus in successful pregnancies

How the immune system adapts to pregnancies has puzzled scientists for decades. Now, findings from an international group of researchers, led by researchers at Karolinska Institutet in Sweden, reveal important changes that occur in the thymus to prevent miscarriages and gestational diabetes. The results are published in the journal Nature. […]
December 24, 2020

A Rare and Exceptional Gift

A woman who defied a genetic mutation that guarantees early-onset Alzheimer’s donates her brain to research. Her life was nothing short of a miracle. Born into an extended family of 6,000, all of whom share a rare genetic mutation that inescapably leads to Alzheimer’s disease (AD) by the age of […]
December 23, 2020

Modified Stem Cells Bring Anti-Cancer Drugs Directly to Malignant Tissues

One of the key difficulties in the treatment of cancer is the fact of its evolution being parallel to our own. This makes developing effective drugs a complex and on-going process. Another challenge faced by researchers is the effective delivery of drugs directly to malignant cells without damaging healthy organs […]
December 22, 2020

White blood cells may cause tumor cell death — but that's not good news

White blood cells are part of many immune system responses in the human body. New research shows that a specific type of those cells may cause brain cancer tissues to die — but that’s not good news, according to researchers at Penn State College of Medicine. They said that higher amounts […]