Related Science News – Page 61 – Innovita Research

Related Science News

March 31, 2021

COVID-19 increases allure of at-home colon cancer tests

A year ago, when the COVID-19 lockdown began, Dr. Rachel Issaka expected that colonoscopies would decline. She was surprised by how much. In the first two months, in-clinic colon cancer screenings fell by 90%.  “I was shocked,” said Issaka, a UW Medicine gastroenterologist and researcher with the Fred Hutchinson Cancer Research Center. There […]
March 31, 2021

Cancer: a bitter disease that thrives in a bitter environment

When cancer invades the brain, normal salt levels are quickly thrown off-kilter, but detecting this change in patients has been difficult. A team of Yale researchers has developed a non-invasive way to observe these changes in close detail at the early stages of cancer growth. This method, developed in the […]
March 31, 2021

New research on vitamin D and respiratory infections important for risk groups

Earlier studies have shown that supplementary vitamin D seems to provide a certain degree of protection against respiratory infections. A new study involving researchers from Karolinska Institutet has now made the most comprehensive synthesis to date of this connection. The study, which is published in the journal Lancet Diabetes & […]
March 31, 2021

T cells recognize recent SARS-CoV-2 variants

When variants of SARS-CoV-2 (the virus that causes COVID-19) emerged in late 2020, concern arose that they might elude protective immune responses generated by prior infection or vaccination, potentially making re-infection more likely or vaccination less effective. To investigate this possibility, researchers from the National Institute of Allergy and Infectious […]
March 31, 2021

Younger age of first cannabis use or prescription drug misuse is associated with faster development of substance use disorders

A new study shows that in the time after first trying cannabis or first misusing prescription drugs, the percentages of young people who develop the corresponding substance use disorder are higher among adolescents (ages 12-17) than young adults (ages 18-25). In addition, 30% of young adults develop a heroin use […]
March 31, 2021

Penn Medicine Researchers Reveal How a Cell Mixes its Mitochondria Before It Divides

In a landmark study, a team led by researchers at the Perelman School of Medicine at the University of Pennsylvania has discovered—and filmed—the molecular details of how a cell, just before it divides in two, shuffles important internal components called mitochondria to distribute them evenly to its two daughter cells. […]
March 31, 2021

Turning back the clock on a severe vision disorder

Gustavo Aguirre and William Beltran, veterinary ophthalmologists and vision scientists at the University of Pennsylvania School of Veterinary Medicine, have studied a wide range of different retinal blinding disorders. But the one caused by mutations in the NPHP5 gene, leading to a form of Leber congenital amaurosis (LCA), is one of the most severe. […]
March 31, 2021

UC Consortium Launches First Clinical Trial Using CRISPR to Correct Gene Defect That Causes Sickle Cell Disease

Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient’s own blood-forming stem cells. The trial will combine CRISPR […]
March 31, 2021

NeuroBasis, a new multi-institution project, is launched

As the ability of medicine to diagnose diseases expands, so does the need for science to decipher their causes. To that end, a team of neuroscientists at the Montreal Clinical Research Institute, affiliated with Université de Montréal, has launched a new project called NeuroBasis. It’s an $8M, a multi-institution collaboration […]
March 31, 2021

A new way to visualize mountains of biological data

Researchers led by the University of Missouri create a new method for analyzing large amounts of biological data to help scientists draw faster conclusions for possible treatments. Studying genetic material on a cellular level, such as single-cell RNA-sequencing, can provide scientists with a detailed, high-resolution view of biological processes at […]
March 31, 2021

Researchers craft AI-based tool that detects bipolar disorder at earlier stages

Many people with early-stage or first-episode bipolar disorder have cognitive deficits, such as issues with visual processing and spatial memory, but those deficits are often so subtle that the disorder can go undiagnosed for years. That could change thanks to researchers at the University of Alberta who have created a […]
March 31, 2021

Study Illuminates the Molecular Details of Lung Development

Researchers at the Perelman School of Medicine at the University of Pennsylvania have produced a detailed molecular atlas of lung development, which is expected to be a fundamental reference in future studies of mammalian biology and of new treatments for diseases, such as COVID-19, that affect the lungs. The researchers, […]
March 31, 2021

Study identifies potential biomarkers for cognitive struggles after surgery

But up to half of older patients undergoing surgery face a lesser-known but similarly formidable cognitive challenge: postoperative delirium, a condition triggered by a surgery that requires anaesthesia and whose trademarks are confusion, disturbed mental faculties, loss of orientation and anxiety. In the worst cases, postoperative delirium leads to extended […]
March 30, 2021

Study shows loss of gene function is causal to congenital heart disease

A team of researchers co-led by Michael Frohman of Stony Brook University has identified an important cause of congenital heart disease. The researchers discovered that certain loss of functions in the PLD1 (phospholipase D1) gene causes congenital right-sided cardiac valve defects and neonatal cardiomyopathy. The findings are detailed in a paper in […]
March 30, 2021

New anticancer drug targets low-oxygen environment of solid tumors

Researchers are perfecting a new generation of anticancer drugs that will be able to specifically target the low-oxygen environment of solid tumors. So far, the new drug has been tested in preliminary experiments with human tumors transplanted into otherwise healthy adult mice. Low oxygen levels among the densely packed cells […]
March 29, 2021

Measurable changes in brain activity during first few months of studying a new language

A study with first-time learners of Japanese has measured how brain activity changes after just a few months of studying a new language. The results show that acquiring a new language initially boosts brain activity, which then reduces as language skills improve. “In the first few months, you can quantitatively […]
March 29, 2021

Prior COVID infection primes immune response to one dose of Pfizer/BioNTech vaccine

People previously infected with SARS-CoV-2 show significantly higher T cell and antibody responses following a single dose of Pfizer/BioNTech vaccine compared with uninfected individuals, a collaborative study involving University of Liverpool researchers has found, While both groups show robust immune responses after one dose, the higher response experienced by previously […]
March 29, 2021

ORNL meets key FDA milestone for cancer-fighting Ac-225 isotope

A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs. The U.S. Food and Drug Administration recently acknowledged receipt of Oak Ridge National Laboratory’s drug master file for actinium-225 nitrate, which enables pharmaceutical companies to reference the document to […]
March 28, 2021

Common Alzheimer’s treatment linked to slower cognitive decline

Cholinesterase inhibitors are a group of drugs recommended for the treatment of Alzheimer’s disease, but their effects on cognition have been debated and few studies have investigated their long-term effects. A new study involving researchers from Karolinska Institutet and published in the journal Neurology shows persisting cognitive benefits and reduced […]
March 28, 2021

World-first clinical trial targets immune molecule IL23 as potential treatment for sarcoma

Sydney researchers are testing whether an existing medication could be repurposed to treat sarcoma. Recruitment is now open for a national clinical trial that will test whether an existing therapy for psoriasis can help treat patients with sarcomas, which are rare cancers arising in the connective tissues (bone, muscle, tendons, […]
March 27, 2021

New Clues to Classic Cancer Target Found in Immune Cells

New clues to a long-pursued drug target in cancer may reside within immune cells, researchers at the University of Michigan Rogel Cancer Center have discovered. The findings, which appear in Nature Immunology, not only shed new light on cancer immunology, they also suggest clinical trials related to this key target — an interaction that […]
March 27, 2021

Engineered immune cells deliver anticancer signal, prevent cancer from spreading

Scientists have genetically engineered immune cells, called myeloid cells, to precisely deliver an anticancer signal to organs where cancer may spread. In a study of mice, treatment with the engineered cells shrank tumors and prevented the cancer from spreading to other parts of the body. The study, led by scientists […]
March 27, 2021

DNA damage “hot spots” discovered within neurons

Researchers at the National Institutes of Health (NIH) have discovered specific regions within the DNA of neurons that accumulate a certain type of damage (called single-strand breaks or SSBs). This accumulation of SSBs appears to be unique to neurons, and it challenges what is generally understood about the cause of […]
March 27, 2021

Research Group Identifies Potential Therapeutic Target for Lupus

A recent study published in JCI found that a neutrophil’s endoplasmic reticulum, the organelle that normally makes proteins in the cell, becomes stressed in the autoimmune disorder lupus. This stress activates a molecule called IRE1α, which appears to play a critical role in lupus pathogenesis in mice. A multidisciplinary research group at the University […]
March 27, 2021

Preparing for exascale: Aurora supercomputer to help scientists visualize the spread of cancer

Scientists are preparing a cancer modeling study to run on Argonne’s upcoming Aurora supercomputer before it goes online in 2022. The U.S. Department of Energy’s (DOE) Argonne National Laboratory will be home to one of the nation’s first exascale supercomputers when Aurora arrives in 2022. To prepare codes for the architecture and scale of […]
March 27, 2021

Research reveals how the brain inhibits remyelination in MS and how to treat it

Two papers by University at Buffalo researchers reveal important new findings as to how regeneration of myelin in multiple sclerosis fails and, potentially, more efficient ways to treat it. The findings include the first demonstration that an existing drug, currently being studied as a cancer therapy, can alter key signalling […]
March 27, 2021

Predicting when epileptic seizures will happen

Epileptics, listen up: imagine being able to have a “weather forecast for your brain,” a way to get advance of the onset of your next seizure, thanks to a microchip planted under your scalp. Science fiction, you think? Not for two researchers at the Centre hospitalier de l’Université de Montréal […]
March 27, 2021

How cells transport molecules with ‘active carpets’

New research provides insights into the process of diffusion in living systems, with implications from novel active coatings to understanding how pathogens are cleared from lungs. A drop of food colouring slowly spreading in a glass of water is driven by a process known as diffusion. While the mathematics of […]
March 27, 2021

Study finds evidence of Bartonella infection in schizophrenia patients

A new study led by University of Wisconsin–Madison School of Veterinary Medicine professor Erin Lashnits shows evidence of Bartonella infection in the blood of people with schizophrenia and schizoaffective disorder. “Researchers have been looking at the connection between bacterial infection and neuropsychiatric disease for some time,” Lashnits says in a news release by North Carolina […]
March 26, 2021

Quantitative Detection of Fatty Liver Disease by Assessing Fat Distribution in the Liver

Excessive fat accumulation in the liver can lead to serious medical problems, including liver failure. Thus, understanding the distribution of lipids within the liver is a critical step in diagnosing fatty liver diseases. A team of researchers at Tokyo University of Science has now shown that near-infrared hyperspectral imaging permits […]