Related Science News

March 1, 2021

Research shows how the brain reorganises old memories when new ones are laid down

Researchers have discovered that the arrangement of existing memories in the brain is altered when we embed new memories. In fact, brain architecture is sophisticated enough to integrate new information while allowing new and old memories to interact, rather than having to forget old experiences to make room for new […]
March 1, 2021

Common artificial sweeteners may be contributing to antibiotic resistance

Artificial sweeteners are very useful for people who do not tolerate sugar. We all need some sweetness in our lives to bring out the flavours of the tea or make coffee a little less bitter. Saccharin, aspartame and other common artificial sweeteners  are great alternatives to sugar. However, a new […]
February 28, 2021

Genotoxic E. coli “caught in the act”

Escherichia coli bacteria are constitutive members of the human gut microbiota. However, some strains produce a genotoxin called colibactin, which is implicated in the development of colorectal cancer. While it has been shown that colibactin leaves very specific changes in the DNA of host cells that can be detected in colorectal […]
February 28, 2021

Oxygen deficit makes nerve cells grow

Oxygen deficit, also called hypoxia, in the brain is actually an absolute state of emergency and can permanently damage nerve cells. Nevertheless, there is growing evidence that to a certain extent, hypoxia can also be an important signal for growth. Together with scientists from the University Hospitals of Copenhagen and […]
February 28, 2021

Some sperms poison their competitors

Competition among sperm cells is fierce – they all want to reach the egg cell first to fertilize it. A research team from Berlin now shows in mice that the ability of sperm to move progressively depends on the protein RAC1. Optimal amounts of active protein improve the competitiveness of […]
February 28, 2021

Reading between the lines of the genome

An international team of researchers discovered a rare genetic disease characterized by severe malformations of the limbs. As  scientists from the Max Planck Institute for Molecular Genetics describe, the condition is caused by a newly identified epigenetic mechanism involving sequences of the genome with previously unknown function. This process could also […]
February 28, 2021

Healing with hydrogels

Inspired by personal tragedy, graduate student Hyunwoo Yuk used his background in soft materials to develop a bioadhesive tape for repairing damaged tissue. In November, mechanical engineering PhD candidate Hyunwoo Yuk earned the top prize at the Collegiate Inventors Competition hosted by the National Inventor’s Hall of Fame. Yuk was […]
February 28, 2021

New type of bone cell could reveal targets for osteoporosis treatment

Researchers at the Garvan Institute of Medical Research have discovered a new type of bone cell that may reveal new therapeutic approaches for osteoporosis and other skeletal diseases. The new cells, which the researchers term ‘osteomorphs’, are found in the blood and bone marrow, and fuse together to form osteoclasts, […]
February 28, 2021

Study: fading memories make childhood trauma research a challenge in adults

A new study from the University of Iowa finds that the limitations of human memory make it difficult for researchers to link adverse childhood experiences to physical health issues later in life. The researchers found that so many people either forget what happened to them in childhood or don’t remember it […]
February 28, 2021

Vanderbilt-developed obesity treatments will be advanced through collaboration with Soleno Therapeutics

A new partnership between Vanderbilt University’s Warren Center for Neuroscience Drug Discovery and clinical-stage biopharmaceutical company Soleno Therapeutics will further research into new clinical treatments for multiple obesity syndromes. Leading the collaboration are WCNDD director Craig Lindsley, who holds the William K. Warren, Jr. Chair in Medicine, and Jerod Denton, professor of anesthesiology and pharmacology […]
February 28, 2021

New Model Predicts Cancer Drug Efficacy Across and Within Cancer Types

The goal of “precision oncology” is to be able to tailor treatments to each individual patient based on their cancer’s unique molecular fingerprints. New technologies and large, “-omics” datasets are now allowing researchers to examine shared features not just within a single type of cancer — such as breast cancer […]
February 27, 2021

Identification of ‘violent’ processes that cause wheezing could lead to better diagnosis and treatment for lung disease

A team of engineers has identified the ‘violent’ physical processes at work inside the lungs which cause wheezing, a condition that affects up to a quarter of the world’s population. The researchers, from the University of Cambridge, used modelling and high-speed video techniques to show what causes wheezing and how […]
February 27, 2021

Researchers detect key flaw in brain modeling

A type of cell derived from human stem cells that has been widely used for brain research and drug development may have been leading researchers astray for years, according to a study from scientists at Weill Cornell Medicine and Columbia University Irving Medical Center. The cell, known as an induced […]
February 27, 2021

Fungi in the gut prime immunity against infection

Common fungi, often present in the gut, teach the immune system how to respond to their more dangerous relatives, according to new research from scientists at Weill Cornell Medicine. Breakdowns in this process can leave people susceptible to deadly fungal infections. The study, published in Cell, reveals a new twist […]
February 27, 2021

Tumor microenvironment helps aggressive lymphomas

The environment surrounding the cancerous cells of a lymphoma tumor has a strong influence on the progression of these blood-cell cancers and their responses to therapies, according to a new study by Weill Cornell Medicine investigators. Measuring this molecular and cellular environment, or “microenvironment,” appears to represent a new type […]
February 27, 2021

Study finds ‘Achilles’ heel’ of Crohn’s-linked bacteria

The discovery of an “Achilles’ heel” in a type of gut bacteria that causes intestinal inflammation in patients with Crohn’s disease may lead to more targeted therapies for the difficult-to-treat disease, according to researchers at Weill Cornell Medicine and NewYork-Presbyterian. In a study published in Cell Host and Microbe, the investigators showed […]
February 27, 2021

Gene critical to immune cell development identified

Much of the three-dimensional architecture of the genome in antibody-producing immune cells is dependent on a gene called SMC3. When this gene is not working properly it can lead to improper immune cell development and to cancer, by disrupting how DNA is structured inside the cell nucleus, according to a […]
February 27, 2021

Genetics May Play Role in Determining Immunity to COVID-19

Neutralizing antibodies develop within two weeks of a SARS-CoV-2 infection, but their durability and intensity can vary by individual, prompting concerns about the prospects of long-lasting immunity and efficacy of COVID-19 vaccines. In a PLOS ONE paper researchers at University of California San Diego School of Medicine report that individual immune […]
February 27, 2021

First-in-Human Clinical Trial to Assess Gene Therapy for Alzheimer’s Disease

UC San Diego researchers will inject harmless virus carrying a restorative gene into participants’ brains, where earlier animal studies suggest it may slow, prevent or reverse progression of the neurological disorder. Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to […]
February 27, 2021

Last-Itch Effort: Fighting the Bacteria That Exacerbate Eczema with Bacteria

In a new study out of University of California San Diego School of Medicine, researchers have identified a universal strain of bacteria derived from healthy human skin that can treat the most common type of eczema, also known as atopic dermatitis. In the paper published in Nature Medicine, the research […]
February 27, 2021

A new way beckons to treat severe obesity

New research by a prestigious Université de Montréal researcher could pave the way for the treatment of early morbid familial obesity, a disease that affects four to six per cent of people suffering from early severe obesity. Co-authored by Michel Bouvier and Patricia René of UdeM’s Institute for Research in […]
February 27, 2021

Bioinformatics tool accurately tracks synthetic DNA

Tracking the origin of synthetic genetic code has never been simple, but it can be done through bioinformatic or, increasingly, deep learning computational approaches. Though the latter gets the lion’s share of attention, new research by computer scientist Todd Treangen of Rice University’s Brown School of Engineering is focused on whether sequence alignment and pan-genome-based methods can outperform recent […]
February 27, 2021

Weill Neurohub joins with Genentech, Roche to advance neuroscience research

The University of California, San Francisco (UCSF) and UC Berkeley announced a long-term research partnership with Genentech, a member of the Roche Group, and its parent company, Roche Holding AG, to speed the development of new therapeutics for debilitating brain diseases and disorders of the central nervous system (CNS), such […]
February 26, 2021

Researchers take an early step toward leukemia drug therapy

A McMaster stem cell research team has made an important early step in developing a new class of therapeutics for patients with a deadly blood cancer. The team has discovered that for acute myeloid leukemia (AML) patients, there is a dopamine receptor pathway that becomes abnormally activated in the cancer […]
February 26, 2021

Scientists capture the choreography of a developing brain

The formation of a brain is one of nature’s most staggeringly complex accomplishments. The intricate intermingling of neurons and the labyrinth of connections also make it a particularly difficult feat for scientists to study. Now, Yale researchers and collaborators have devised a strategy that allows them to see this previously […]
February 26, 2021

New strategy blocks chronic lung disease in mice

Inflammatory lung diseases such as asthma, COPD and, most recently, COVID-19, have proven difficult to treat. Current therapies reduce symptoms and do little to stop such diseases from continuing to damage the lungs. Much research into treating chronic inflammatory diseases has focused on blocking chemicals called cytokines, which trigger cascades […]
February 26, 2021

New experiences enhance learning by resetting key brain circuit

A study of spatial learning in mice shows that exposure to new experiences dampens established representations in the brain’s hippocampus and prefrontal cortex, allowing the mice to learn new navigation strategies. The study, published in Nature, was supported by the National Institutes of Health. “The ability to flexibly learn in new […]
February 26, 2021

NIH study: people with SARS-CoV-2 antibodies may have a low risk of future infection

People who have had evidence of a prior infection with SARS-CoV-2, the virus that causes COVID-19, appear to be well protected against being reinfected with the virus, at least for a few months, according to a newly published study from the National Cancer Institute (NCI). This finding may explain why reinfection appears […]