Related Science News – Page 56 – Innovita Research

Related Science News

April 2, 2019

‘Jumping genes’ drive many cancers

Mistakes in DNA are known to drive cancer growth. But a new study, from Washington University School of Medicine in St. Louis, heavily implicates a genetic phenomenon commonly known as “jumping genes” in the growth of tumors. The study is published in the journal Nature Genetics. Since jumping genes aren’t […]
April 2, 2019

Researchers target metastasis in fight against cancer

An experimental combination drug therapy attacking the DNA integrity of cancer cells is showing promise for a possible new cancer therapy in the future. Scientists at the University of Alberta used two drugs together to enhance DNA damage to human breast cancer cells in mice and reduce their capacity to […]
April 2, 2019

Most precise measurements of sickle cell disease building blocks could lead to new treatments

In a breakthrough study of sickle cell disease, biomedical engineers in the University of Minnesota College of Science and Engineering have revealed that the building blocks of the disease are much less efficient at organizing than previously thought. The findings open the door to new treatments, including new medicines that […]
April 2, 2019

Introducing a kinder, gentler way to blow holes in cells

When scientists attempt to slip big molecules, like the Cas9 enzyme that is key to CRISPR gene editing, into cells, things can get messy. One popular technique, bulk electroporation, involves jolting cells with electricity. This blows holes everywhere in the cell, allowing anything and everything to get inside. Delicate cells, […]
April 2, 2019

3D-printed tissues may keep athletes in action

Bioscientists are moving closer to 3D-printed artificial tissues to help heal bone and cartilage typically damaged in sports-related injuries to knees, ankles and elbows. Scientists at Rice University and the University of Maryland reported their first success at engineering scaffolds that replicate the physical characteristics of osteochondral tissue – basically, hard bone beneath a […]
April 2, 2019

Breakthrough Study of Cell Signaling Holds Promise for Immune Research and Beyond

A team of physical chemists led by Berkeley Lab has unraveled the inner workings of a process that allows hard-working T cells to tune out fake signals. For the first time ever, scientists have imaged the process by which an individual immune system molecule is switched on in response to […]
April 1, 2019

Biologists find a way to boost intestinal stem cell populations

Cells that line the intestinal tract are replaced every few days, a high rate of turnover that relies on a healthy population of intestinal stem cells. MIT and University of Tokyo biologists have now found that aging takes a toll on intestinal stem cells and may contribute to increased susceptibility […]
April 1, 2019

Visualizing better cancer treatment

A team of researchers from New York University has engineered nanoscale protein micelles capable of both delivering chemotherapeutic drugs and of being tracked by magnetic resonance imaging (MRI). The innovation falls into the category of “theranostics,” meaning that it combines diagnostic capability and drug delivery, allowing researchers to administer therapy […]
April 1, 2019

Scientists find metabolic target to prevent, treat heart failure at earliest stage

Researchers with The Ohio State University College of Medicine and The Ohio State University Wexner Medical Center have identified a metabolic process in the heart that, if treated, could someday prevent or slow the progression of heart failure. The American Heart Association journal published in the Circulation. Before any physical signs or symptoms of heart […]
April 1, 2019

Harnessing T-cell “stemness” could enhance cancer immunotherapy

A new study led by scientists in the Center for Cancer Research (CCR) at the National Cancer Institute (NCI) sheds light on one way tumors may continue to grow despite the presence of cancer-killing immune cells. The findings, published in Science, suggest a way to enhance the effectiveness of immunotherapies […]
April 1, 2019

Trial to answer dilemma of treating childhood epilepsy

One of the largest ever clinical trials in children with Rolandic epilepsy, coordinated by the University of Liverpool, is launching on ‘Purple Day’, the family-focused epilepsy awareness day. Researchers from the Clinical Trials Research Centre at the University of Liverpool have been involved with designing and coordinating the nationwide CASTLE trial, which is one […]
April 1, 2019

Neuropathy Study Finds Promise in Healthy Fats

People who are diabetic, prediabetic or obese are at high risk of developing diabetic neuropathy, which is chronic nerve damage that often affects the feet and hands. Researchers at Michigan Medicine may have identified a new way to reverse this common, painful and debilitating condition through simple changes in diet. […]
April 1, 2019

New medication gives mice bigger muscles

Researchers from Aarhus University have studied a new group of medicinal products which increase the muscle- and bone mass of mice over a few weeks. This offers hope to the elderly and people suffering from weak muscles and bones due to illness. It is common knowledge that as people grow […]
April 1, 2019

Dissolving the Gordian Knot

In a great stride toward finding an effective treatment for early-stage neurodegenerative diseases, UC Santa Barbara neurobiologist Kenneth S. Kosik and collaborators have uncovered a “druggable” mechanism of pathological tau protein aggregation. For the millions of people at risk for frontotemporal dementia and a host of other such conditions including Alzheimer's, this […]
March 29, 2019

When Does It Become Morally Wrong to Engineer Your Children Genetically

All parents want their children to be not only healthy but also better than them in many ways. Can genetic engineering help them achieve that? Scientific and Moral Aspects of Genetic Modification Gene manipulation has made colossal strides over the last decades. Scientists claim that genetic engineering of children has […]
March 29, 2019

First disease caused by defective myoglobin discovered

Researchers at Karolinska Institutet have discovered the underlying cause of a hereditary muscle disease first characterised in a Swedish family in 1980. It proves to be the first identified disease caused by defective myoglobin, the protein that transports oxygen in muscle cells. The study is published in Nature Communications. Sarcoplasmic body […]
March 29, 2019

Cannabis during pregnancy bumps psychosis risk in offspring

Pregnant women who use cannabis may slightly increase the risk their unborn child will develop psychosis later in life, suggests new research from Washington University in St. Louis. “Our research shows that prenatal marijuana exposure after maternal knowledge of pregnancy is associated with a small increase in psychosis proneness during […]
March 29, 2019

Testosterone discovery may explain low levels in men with diabetes

Scientists at the University of Virginia and elsewhere have mapped out how the body transports testosterone, and their surprising findings may explain low testosterone levels seen in men with diabetes or patients on certain medications. The discovery allows scientists to understand exactly how testosterone, the male sex hormone, binds to a […]
March 29, 2019

Clear Advance for Corneal Regeneration

An adhesive gel packed with light-activated chemicals can seal cuts or ulcers on the cornea, the clear surface of the eye, and then encourage the regeneration of corneal tissue, according to a preclinical study by Harvard Medical School researchers at Massachusetts Eye and Ear published online in Science Advances. The new […]
March 29, 2019

Personalized in vitro model enables drug screening for kidney cancer

A new UW Carbone Cancer Center study, published online in EBioMedicine, has developed a model that mimics the tumor’s blood supply on a three-dimensional  platform designed in the laboratory of Dr. David Beebe, professor of biomedical engineering and pathology. The authors of the study, led by Drs. Jose “Tony” Jimenez-Torres and Maria […]
March 29, 2019

Engineered Vessels Evolve into Living Tissue

In one of the longest follow-up studies of its kind, researchers found that their specially bioengineered blood vessels evolved into living tissue after human implantation. Researchers from Yale and the North Carolina-based company Humacyte published results in Science Translational Medicine on the progress of their bioengineered human vessels (HAVs). The results show […]
March 28, 2019

Study: Brain Stem Cells Age Faster in MS Patients

Brain stem cells in people with the most severe form of multiple sclerosis look much older than they really are, according to a study led by UConn Health and published in the Proceedings of the National Academy of Sciences (PNAS). The prematurely old cells act differently in the brain than normal ones, […]
March 28, 2019

Study gives new perspective on production of blood cells and immune cells

A healthy adult makes about 2 million blood cells every second, and 99 percent of them are oxygen-carrying red blood cells. The other one percent are platelets and the various white blood cells of the immune system. How all the different kinds of mature blood cells are derived from the […]
March 28, 2019

Study in mice examines impact of reused cooking oil on breast cancer progression

A new study in mice suggests that consuming the chemical compounds found in thermally abused cooking oil may trigger genetic changes that promote the progression of late-stage breast cancer. Thermally abused frying oil – cooking oil that has been repeatedly reheated to high temperatures – may act as a toxicological […]
March 28, 2019

New website walks parents through early childhood development, alerts them to early signs of autism

Your baby delights you but he’s causing you concern. Why is it so hard to get him to look at you? Why doesn’t he gesture as much as other babies you know? Your relatives say you worry too much. They blame your parenting for the child’s frequent tantrums. Still, you […]
March 28, 2019

Lab grown "brains" successfully model disease

The human brain is one of the most complex organs. Its complexity challenges our ability to study its structure and function. As a result, many brain-related diseases are not fully understood and adequate treatments are often lacking. Scientists from Max Planck Institute of Psychiatry were able to model a developmental […]
March 28, 2019

Obesity and emotional problems develop together as children age, study shows

High BMI and mental ill-health go increasingly hand-in-hand to present a combined health risk for children from mid-childhood, according to a new study. Researchers from the University of Liverpool and University College London analysed data on more than 17,000 children born across the UK in 2000-01, who are taking part […]
March 28, 2019

Tumor-Associated Immune Cells Hinder Frontline Chemotherapy Drug in Pancreatic Cancer

A frontline chemotherapy drug given to patients with pancreatic cancer is made less effective because similar compounds released by tumor-associated immune cells block the drug’s action, research led by the University of Michigan Rogel Cancer Center found.The chemotherapy drug gemcitabine is an anti-metabolite. It’s similar to normal metabolites taken up by the […]
March 28, 2019

New Study Identifies Causative Genes in Osteoporosis

Researchers identified two novel genes that affect bone-formation cells relevant to fractures and osteoporosis; understanding these genes could lead to more effective treatments. Examining a person’s DNA can help scientists understand if the individual is at risk for osteoporosis, the chronic bone-weakening condition that affects millions of Americans. In a […]
March 28, 2019

Exercising is good for your brain, but how?

Physical exercise is good for you. You already know that and if you are not exercising is just because you are too lazy. However, it is still quite strange that exercising is not only good for your body, but for your brain as well. How? An international team from The […]