Related Science News – Page 16 – Innovita Research

Related Science News

April 23, 2019

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

Treating breast tumors with two cancer drugs simultaneously may prevent endocrine resistance by attacking the disease along two separate gene pathways, scientists at the University of Illinois found in a new study. The two drugs used in the study, selinexor and 4-OHT, caused the cancer cells to die and tumors […]
April 23, 2019

Common anti-inflammatory could protect baby brains

Administering ibuprofen immediately after birth may reduce brain damage in tiny growth-restricted babies, University of Queensland researchers have found. The UQ Centre for Clinical Research’s Dr Julie Wixey said the drug could help reduce the incidence of serious long-term neurological problems in these babies. “It’s often difficult to diagnose babies at risk of being […]
April 23, 2019

‘Super-Hero’ Stem Cells Survive Radiation to Regrow Muscles

Muscle damage is a common side effect of radiation therapy for cancer treatment, and is made worse because the very stem cells responsible for repairing injured muscles typically bear the brunt of radiation damage. Now UC San Francisco researchers have discovered a new type of stem cell in mouse muscles […]
April 23, 2019

Stanford doctors, materials scientists hope a blood test will encourage more colon cancer screenings

Colorectal cancer is the second leading cause of cancer deaths in the U.S. and a growing problem around the world, but not because it’s a particularly difficult cancer to detect and halt. The problem, doctors and researchers believe, is that not enough people are being screened for early signs of […]
April 23, 2019

‘Longevity gene’ responsible for more efficient DNA repair

Explorers have dreamt for centuries of a Fountain of Youth, with healing waters that rejuvenate the old and extend life indefinitely. Researchers at the University of Rochester, however, have uncovered more evidence that the key to longevity resides instead in a gene. In a new paper published in the journal Cell, the […]
April 23, 2019

Simple and Fast Method for Radiolabelling Antibodies against Breast Cancer

Radioactive antibodies that target cancer cells are used for medical diagnostics with PET imaging or for targeted radioimmunotherapy. Researchers from the University of Zurich have created a new method for radiolabelling antibodies using UV light. In less than 15 minutes, the proteins are ready-to-use for cancer imaging or therapy. Radioactive […]
April 23, 2019

Healthy meal kits can boost children’s long-term health

A scheme that helped parents plan well-balanced family dinners for three months kept their children healthier for years after, a study has found. Low-income families who were given simple recipe kits to cook five healthy meals a week decreased their children’s body mass index (BMI) compared with peers who continued […]
April 23, 2019

Appetite-regulating hormone levels in breast milk vary by mother’s weight

Nearly 20 percent of children and adolescents and 14 percent of toddlers in the United States are obese. One contributing factor, among many possibilities, may be what a baby eats during their critical first six months of life and how it affects their continued growth. Ideally, breast milk is their […]
April 23, 2019

Treating Excess of One Hormone Shows Promise for Decreasing the Risk of Obstructive Sleep Apnea

Treating the overproduction of one hormone may be a way to help a subset of the millions of Americans who suffer from obstructive sleep apnea, according to a new study. People with obstructive sleep apnea stop breathing for short periods while they are sleeping, which leads to a poor night’s […]
April 19, 2019

New research could prevent jaw damage in patients being treated for cancer or osteoporosis

SC researchers and collaborators report a breakthrough to prevent damage to the jaw, a side effect suffered by some people undergoing treatment for cancer or osteoporosis. The newly published research is an important step toward a cure for osteonecrosis of the jaw, a rare side effect caused by drugs commonly used to […]
April 19, 2019

Gene therapy restores immunity in infants with rare immunodeficiency disease

A small clinical trial has shown that gene therapy can safely correct the immune systems of infants newly diagnosed with a rare, life-threatening inherited disorder in which infection-fighting immune cells do not develop or function normally. Eight infants with the disorder, called X-linked severe combined immunodeficiency (X-SCID), received an experimental […]
April 19, 2019

Fuel for Drug Resistance

About one in eight women in the U.S. will develop breast cancer in her lifetime. The vast majority of these cancers rely on the hormone estrogen to grow. Estrogen-receptor positive (ER+) breast cancer tumors are frequently treated with the drug tamoxifen, which blocks the hormone’s effect on the tumor. However, […]
April 19, 2019

Preventing triple negative breast cancer from spreading

A breast cancer cell is like a house with three locks on the front door. Keys, or receptors, allow drugs to unlock the door and kill the cell. However, in triple-negative breast cancer, these keys are absent, thereby resulting in few options for drug therapy, until now. A protein called […]
April 19, 2019

A ‘virtual’ view with a little bit of math

MU scientists advance a way to track changes in a person’s cardiovascular system Every heart beat sends blood flowing throughout the human body. While an electrocardiogram uses a contact approach to measure the electrical activity of the heart, a ballistocardiogram is a non-contact way of measuring the mechanical effect of […]
April 19, 2019

Bioengineers program cells as digital signal processors

Synthetic biologists have added high-precision analog-to-digital signal processing to the genetic circuitry of living cells. The research, described online in the journal Science, dramatically expands the chemical, physical and environmental cues engineers can use to prompt programmed responses from engineered organisms. Using a biochemical process called cooperative assembly, Caleb Bashor of Rice University, Ahmad “Mo” […]
April 19, 2019

Behavioral disorders in kids with autism linked to reduced brain connectivity

More than a quarter of children with autism spectrum disorder are also diagnosed with disruptive behavior disorders. For the first time, Yale researchers have identified a possible biological cause: a key mechanism that regulates emotion functions differently in the brains of the children who exhibit disruptive behavior. The study appears […]
April 18, 2019

Microbes in the human body swap genes, even across tissue boundaries

Bacteria in the human body are sharing genes with one another at a higher rate than is typically seen in nature, and some of those genes appear to be traveling – independent of their microbial hosts – from one part of the body to another, researchers report in the journal […]
April 18, 2019

Blood pressure drug shows promise for treating Parkinson’s and dementia in animal studies

A prescription drug to treat high blood pressure has shown promise against conditions such as Parkinson’s, Huntington’s and forms of dementia in studies carried out in mice and zebrafish at the University of Cambridge. A common feature of these diseases – collectively known as neurodegenerative diseases – is the build-up […]
April 18, 2019

Maternal gestational diabetes linked to diabetes in children

Children of mothers who had gestational diabetes during pregnancy could be at increased risk of type 1 diabetes themselves, according to a new study led by a team at the Research Institute of the McGill University Health Centre (RI-MUHC) that was published in the Canadian Medical Association Journal (CMAJ). Early detection of […]
April 18, 2019

Healthy hearts need two proteins working together

Two proteins that bind to stress hormones work together to maintain a healthy heart in mice, according to scientists at the National Institutes of Health and their collaborators. These proteins, stress hormone receptors known as the glucocorticoid receptor (GR) and mineralocorticoid receptor (MR), act in concert to help support heart […]
April 18, 2019

Scientists Print First 3D Heart Using Patient’s Own Cells and Materials

In a major medical breakthrough, Tel Aviv University researchers have “printed” the world's first 3D vascularised engineered heart using a patient's own cells and biological materials. Their findings were published in a study in Advanced Science. Until now, scientists in regenerative medicine — a field positioned at the crossroads of biology and technology […]
April 18, 2019

Cancer-Killing Combination Therapies Unveiled with New Drug-Screening Tool

UC San Francisco scientists have designed a large-scale screen that efficiently identifies drugs that are potent cancer-killers when combined, but only weakly effective when used alone. Using this technique, the researchers eradicated a devastating blood cancer and certain solid tumor cells by jointly administering drugs that are only partially effective […]
April 18, 2019

Princeton scientists discover an interaction that helps cancers spread to bone

“A large majority of human cancers are carcinomas derived from epithelial cells,” said Kang, a professor of molecular biology and the corresponding author of the paper. Carcinomas grow from a single mutated cell into a tumor, a solid mass of cancerous cells. As long as it remains contained at its […]
April 17, 2019

Indicators of Mental Illness and Despair on the Rise among Gen X-ers, Study Suggests

A new study looking at the mental health of so-called Gen X-ers (i.e., people born between 1974-1983), published in the American Journal of Public Health, shows a marked increase in the tell-tale signs of despair, often characterised by depression, thoughts of suicide, drug use, and excessive drinking. Back in 2016, […]
April 17, 2019

Molecular switch for the X chromosome

A large number of genes have to be switched on or off at different times during development. A particular challenge occurs when two copies of the same gene must acquire opposing states of activation within the same cell, as it is the case, for example, for the two X chromosomes in […]
April 17, 2019

Genetic defects without consequences

Many diseases are caused by genetic defects. However, their severity can vary among individual patients, so that even mild forms can occur. Scientists at the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now decrypted a molecular mechanism responsible for this phenomenon. Accordingly, the mRNA of […]
April 17, 2019

The fluid that feeds tumor cells

Before being tested in animals or humans, most cancer drugs are evaluated in tumor cells grown in a lab dish. However, in recent years, there has been a growing realization that the environment in which these cells are grown does not accurately mimic the natural environment of a tumor, and […]
April 17, 2019

Redefining the world of cancer

More than a decade ago, UCI biology professor Arthur Lander, broadened the focus of his research. Instead of studying a particular biological molecule or specific cell type, he reasoned that biomedical researchers would learn more, at a faster pace, if they explored biological systems — how networks of molecules, cells, tissues, […]
April 17, 2019

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer’s disease, researchers show

Alzheimer’s is a disease of aggregation. Neurons in the human brain make a protein called amyloid beta. Such proteins on their own, called monomers of amyloid beta, perform important tasks for neurons. But in the brains of people with Alzheimer’s disease, amyloid beta monomers have abandoned their jobs and joined together. First, […]
April 17, 2019

Alternative Landscape

The recent emergence of immunotherapy has marked a sea change in research and care for many forms of cancer, bringing new hope to patients and families around the world. For those who respond to treatment, the results can be dramatic. Activation of a patient’s immune system against cancer can kill […]