Related Science News

December 7, 2018

Prenatal exposure to chemicals in personal care products may speed puberty in girls

Girls exposed to chemicals commonly found in toothpaste, makeup, soap and other personal care products before birth may hit puberty earlier, according to a new longitudinal study led by researchers at UC Berkeley. The results, which were published in the journal Human Reproduction, came from data collected as part of the […]
December 7, 2018

NIH-funded tissue chips rocket to International Space Station

When traveling in space, astronauts experience physiological changes normally associated with aging, such as bone loss, muscle deterioration and altered immune systems. When the astronauts return to Earth, the changes often reverse. To better understand the relevance of the astronauts’ experience to human health — both on the ground and […]
December 7, 2018

Older women who suffer from tooth loss are more likely to develop high blood pressure

Postmenopausal women who have experienced loss of all teeth are at higher risk of developing high blood pressure, according to a University at Buffalo study published Dec. 4 in the American Journal of Hypertension. Multiple studies have suggested an association between periodontal disease and tooth loss with hypertension, but the […]
December 7, 2018

Scientists to produce anti-cancer drugs in yeast

Nature is so complex that natural molecules used for i.e. cancer treatment still can’t be produced by chemical synthesis. Today, major chemical and pharmaceutical companies harvest large amounts of rare plants and seeds in order to extract valuable substances. But the production methods based on extracts from natural resources are […]
December 6, 2018

Researchers classify Alzheimer's patients into 6 subgroups

Researchers studying Alzheimer’s disease have created an approach to classify patients with Alzheimer’s disease, a finding that may open the door for personalized treatments. “Alzheimer’s, like breast cancer, is not one disease,” said lead author Shubhabrata Mukherjee, research assistant professor of medicine at the University of Washington School of Medicine. ”I […]
December 6, 2018

Researchers at MU identify enzyme responsible for helping cancer tumors spread

Researchers at the University of Missouri have unraveled how a cancer-critical enzyme is positioned on cell surfaces. The enzyme enables tumor cells to tunnel through collagen, creating a convenient path for tumors to spread cancer throughout the body. This breakthrough is an important step toward the development of pharmaceuticals that can prevent […]
December 5, 2018

Vascudyne to commercialize biologic engineered tissue with potential to transform medical device technology

University of Minnesota Technology Commercialization today announced the formal launch of Vascudyne Inc., a startup company based in Stillwater, Minn., focused on the development of biologically engineered tissue for medical device and therapeutics applications. The technology offers a regenerative capacity unavailable until now in materials and devices used for medical […]
December 5, 2018

New possible target for treating major common diseases

There is a large, untapped potential for developing drugs against cancer, fibrosis and cardiovascular diseases by targeting a family of receptors known as Frizzleds, researchers at Karolinska Institutet in Sweden believe. In a new study published in Science Signaling, they identify how these receptors are activated in the cell membrane and […]
December 5, 2018

World War II weapon used in new battle: combatting Parkinsons disease

Purdue University research shows the antidote can effectively remove acrolein, a neurotoxin produced in the body that is directly correlated with Parkinson’s disease. A World War II chemical weapon antidote is shown to be effective combating a new enemy: Parkinson’s disease. Parkinson’s is characterized by the steady and progressive loss […]
December 4, 2018

Epigenetic Map May Pave Way for New Therapeutic Solutions to Hearing Loss

Epigenetics is the expression and control of genes. The epigenetics involved in the inner ear is a critical part of the mystery of hearing. A team led by Prof. Karen B. Avraham, Vice Dean of the Sackler Faculty of Medicine at Tel Aviv University, has now created the first map of “methylation” — one […]
December 4, 2018

ABCD study completes enrollment, announces opportunities for scientific engagement

The National Institutes of Health announced that enrollment for the Adolescent Brain Cognitive Development (ABCD) Study is now complete and, in early 2019, scientists will have access to baseline data from all ABCD Study participants. There are 11,874 youth, ages 9-10, participating in the study, including 2,100 young people who […]
December 4, 2018

Treating spinal pain with ‘engineered living tissue’ moves closer to reality

For the first time, bioengineered spinal discs were successfully implanted and provided long-term function in the largest animal model ever evaluated for tissue-engineered disc replacement. A new Penn Medicine study published in Science Translational Medicine provides compelling translational evidence that the cells of patients suffering from neck and back pain could be used to […]
December 4, 2018

Experimental cancer drug shows promise for Parkinson’s

A drug originally developed for prostate cancer may have exciting potential for treating Parkinson’s. The study, funded by Parkinson’s UK, suggests that the drug, tasquinimod, which is not yet on the market, works by controlling genes that may cause Parkinson’s. This happens when the drug interacts with a protein inside […]
December 4, 2018

New tools illuminate mechanisms behind overlooked cellular components’ critical roles

In two papers published in the journal Cell, researchers from multiple Princeton departments report on the conditions that lead to the formation of membraneless organelles and the impact that the formation has on cellular DNA. Clifford Brangwynne, associate professor of chemical and biological engineering and leader of the research teams, said the […]
December 4, 2018

The long and short of CDK12

Mutations in the BRCA1 and BRCA2 genes pose a serious risk for breast and ovarian cancer because they endanger the genomic stability of a cell by interfering with homologous recombination repair (HR), a key mechanism for accurately repairing harmful double-stranded breaks in DNA. Without the ability to use HR to […]
December 4, 2018

New drug combination could be more effective against melanoma

A class of cancer drugs called protein kinase inhibitors is one of the most effective treatments for melanoma. However, in many cases, tumors eventually become resistant to the drugs and cause a relapse in the patient. A new study from MIT suggests that combining kinase inhibitors with experimental drugs known […]
December 4, 2018

Study: Immunotherapy Better than Chemotherapy for Subtype of Head and Neck Cancer

A randomized clinical trial involving 97 medical centers in 20 countries, including Moores Cancer Center at UC San Diego Health, found that treating patients who have chemotherapy-resistant head and neck cancer with the immunotherapy drug pembrolizumab is more effective and less toxic than standard chemotherapy, reports an international team of […]
December 4, 2018

First Jellyfish Genome Reveals Ancient Beginnings of Complex Body Plan

Jellyfish undergo an amazing metamorphosis, from tiny polyps growing on the seafloor to swimming medusae with stinging tentacles. This shape-shifting has served them well, shepherding jellyfish through more than 500 million years of mass extinctions on Earth. “Whatever they’re doing has really worked for them,” said David Gold, an assistant professor […]
December 4, 2018

Study reveals new role for methotrexate in fighting cancer

A study of the dual pathways that process the essential vitamin folate by Weill Cornell Medicine investigators unexpectedly revealed a new way the cancer drug methotrexate works and may suggest strategies to boost its cancer-killing effects. For the study, published in Cell, the investigators used genome editing and biochemical experiments […]
December 3, 2018

Microglia: Teasing Out Diversity

Immune cells known as microglia have been found to protect the brain from injury and infection and are critical during brain development, helping circuits wire properly. They also seem to play a role in disease—showing up, for example, around brain plaques in people with Alzheimer’s. In an ambitious study, perhaps […]
December 3, 2018

Plant’s recycling system important in sickness and in health

Reduce, reuse, recycle. Or just stick with recycle. A plant relies on cellular machinery to recycle materials during times of stress, but that same machinery has a remarkable influence on the plant’s metabolism even under healthy growing conditions, according to new research from Washington University in St. Louis. Autophagy is […]
December 1, 2018

Smoking could be linked to schizophrenia and psychosis

You know that smoking is not good for you, but do you know exactly how? Most smokers do not really care to hear about the damaging effects of smoking, although they definitely should remember them. It is not just about an increased risk of lung cancer, yellow teeth, bad smell, […]
November 30, 2018

FDA Approves New Targeted Drug for Leukemia Tested at University of Pennsylvania

The U.S. Food and Drug Administration (FDA) has approved the first ever inhibitor drug specifically approved for treating patients with relapsed or refractory acute myeloid leukemia (AML) with a mutation in the Fms-like tyrosine kinase 3 (FLT3) gene. Patients with these mutations who have relapsed or refractory AML have very […]