Related Science News – Page 97 – Innovita Research

Related Science News

August 26, 2020

Leading-edge Technology Unmasks Protein Linked to Parkinson’s Disease

An elusive protein that many consider the key of fully understanding the causes of genetic Parkinson’s disease has come much more clearly into focus. Impacting millions around the world, Parkinson’s is a neurological disorder that progressively attacks motor functions, leading to lasting damage in movement and coordination, among other areas. […]
August 26, 2020

Excessive Fructose Consumption May Cause a Leaky Gut, Leading to Fatty Liver Disease

Excessive consumption of fructose — a sweetener ubiquitous in the American diet — can result in non-alcoholic fatty liver disease (NAFLD), which is comparably abundant in the United States. But contrary to previous understanding, researchers at University of California San Diego School of Medicine report that fructose only adversely affects […]
August 26, 2020

Inflammatory Bowel Disease Linked to an Immune Cell Run Amok

Inflammatory bowel disease (IBD) is a group of intestinal disorders affecting an estimated six to eight million people worldwide. Although there are many treatments for IBD, a number of patients fail to respond long-term, leaving those afflicted with a host of chronic issues, from abdominal pain and cramping to frequent, […]
August 26, 2020

Uncontrolled ‘cAMP’ Helps Spark Rare Liver Cancer

Since humans first controlled fire, they have camped around it to circulate information, signaling each other when something approaches. Metaphorically, certain molecules have been carrying information around our cells to help regulate bodily functions as needed. One such molecule, called cyclic AMP or “cAMP,” presumably travels freely inside cells managing […]
August 26, 2020

Fresh tumour biopsies in world-first technique for cancer treatments

An innovative technique to improve cancer treatments using tumour biopsies less than 30 minutes after they’re taken has been developed at The University of Queensland. The ‘Drug uptake in ex Vivo tumours’ technique was developed after researchers found fresh patient tumour biopsies responded differently to treatments than the tissue cultures […]
August 26, 2020

Single-Cell RNA Sequencing Sheds New Light on Cancer Cells’ Varied Response to Chemotherapy

Chemotherapy works by attacking rapidly dividing cells within the body. But small pockets of cancer cells can withstand its assault, allowing the cancer eventually to return. Gaining a better understanding of why some cancer cells survive while others die is critical for making chemotherapy more effective, says Jun Hee Lee, Ph.D., […]
August 26, 2020

Newly discovered ‘support system’ for axons suggests a novel therapeutic target for neurodegenerative diseases

Axons are long, finger-like projections of neurons that transmit critical signals throughout the nervous system. But because they are fragile, they are often among the first casualties of certain neurodegenerative diseases, causing symptoms such as muscle weakness or numbness of limbs. New research from the University at Buffalo reveals that […]
August 26, 2020

Detecting pancreatic cancer at treatable stages

Pancreatic cancer is rarely detected at its early stages because symptoms often do not present themselves until after the cancer has progressed. By then, invasive procedures such as surgery, chemotherapy or radiation are often needed to treat the cancer. Now, researchers at the University of Missouri’s College of Veterinary Medicine […]
August 26, 2020

Protein ‘chameleon’ colors long-term memory

A chameleonlike protein in neurons can change its mind, and in the process change our brains. Scientists at Rice University and the University of Texas Health Science Center at Houston (UTHealth) uncovered new clues in the protein CPEB3 as part of their dogged pursuit of the mechanism that allows humans to have […]
August 25, 2020

A simple blood test could predict the success of immunotherapy

Immunotherapy is a promising technology for cancer treatment. Essentially, body’s own immune system is taught how to recognize cancer cells and kill them. When other treatments have failed, immunotherapy can still shrink tumours and prolong survival. However, it doesn’t work for everyone – how to predict which patients could benefit […]
August 25, 2020

Re-engineered enzyme could help reverse damage from stroke, spinal cord injury

A team of researchers from the University of Toronto's Faculty of Applied Science & Engineering and the University of Michigan has redesigned and enhanced a natural enzyme that shows promise in promoting the regrowth of nerve tissue following injury. The new version of the enzyme is more stable and could lead […]
August 25, 2020

Karolinska Institutet, St. Erik Eye Hospital and Novo Nordisk collaborate to find a cure for age-related macular degeneration

Karolinska Institutet and St. Erik Eye Hospital have entered into a collaboration with Novo Nordisk A/S to develop a new treatment for age-related macular degeneration. Novo Nordisk A/S will provide support and SEK 48 million in funding to enable a phase 1 clinical trial where new retinal cells generated from […]
August 25, 2020

BRCA1 and BRCA2 Gene Mutations: The Basics

Mutations in the BRCA1 and BRCA2 genes are linked to the development of breast cancer, ovarian cancer and other types of cancer. Genetic testing and counseling services can determine whether a person carries these mutations and, if they do, how the information could help inform cancer prevention or treatment decisions. In the first of […]
August 25, 2020

Increasing the Arsenal of Radioisotopes in the Fight Against Cancer

A new supply of a critical radioisotope advances personalized medicine. The Science Researchers have deployed a newly developed method to produce large quantities of copper-67. This material is a promising medical radioisotope–isotopes with applications in health care. The increased supply of copper-67 will enable clinical studies for new drug discovery […]
August 25, 2020

Study: MTL deterioration can lead to impulsive decisions

Deterioration of a part of the brain known as the medial temporal lobe can cause an older adult to make more impulsive decisions. One decision-making process — temporal discounting — places a greater value on a smaller and immediate outcome while dismissing a better but delayed outcome: instant gratification, in […]
August 25, 2020

Taking Risks for Big Rewards

Much of the world, including research at Penn Medicine, has focused its attention on how T cells — which play a central role in immune response — might shape the trajectory of COVID-19 infection, and how immunotherapy can shed light on treatment of the disease. Already a leader in immunotherapy research […]
August 24, 2020

New maps of chemical marks on DNA pinpoint regions relevant to many developmental diseases

Salk researchers mapped how DNA methylation changes over time in mice to better understand developmental disorders. In research that aims to illuminate the causes of human developmental disorders, Salk scientists have generated 168 new maps of chemical marks on strands of DNA—called methylation—in developing mice. The data, published July 29, […]
August 24, 2020

Genetic study points to cells responsible for Parkinson’s disease

Scientists have uncovered new insights into the origins of Parkinson’s disease. The team, from the UK Dementia Research Institute at Cardiff University and the Oxford Parkinson’s Disease Centre, University of Oxford, studied the genes of more than 6,000 cells from a region deep in the middle of the brain called the […]
August 24, 2020

Heart attack damage reduced by shielded stem cells

Bioengineers and surgeons from Rice University and Baylor College of Medicine (BCM) have shown that shielding stem cells with a novel biomaterial improve the cells’ ability to heal heart injuries caused by heart attacks. In a study using rodents, a team led by Rice’s Omid Veiseh and Baylor’s Ravi Ghanta showed it could […]
August 22, 2020

Alzheimer's risk can be predicted as early as teenage years

Alzheimer’s disease is a debilitating condition that is going to touch millions of aging people. It is incurable, even if treatment options are slowly getting better. Early start on these treatments is probably the best bet, but how can you predict that the person is going to develop Alzheimer’s before […]
August 21, 2020

Studying how skin cancer starts

Luis Ortiz-Rodríguez grew up on the beaches of Puerto Rico—surfing, swimming, and running in the hot sand—and swears he had never put on sunblock a day in his life. Then the day came when he peered through an ultrafast laser spectrometer at the College of Arts & Sciences and observed […]
August 21, 2020

Unique protein structures could hold the key to treatment for Parkinson’s disease

Scientists at the University Bath have discovered a series of protein structures that are thought to be highly relevant to the onset of Parkinson’s disease. It is hoped that further analysis of these structures will open up a new avenue for a potential treatment for a disease that is the […]
August 21, 2020

New 'molecular computers' find the right cells

Scientists have demonstrated a new way to precisely target cells by distinguishing them from neighboring cells that look quite similar. Even cells that become cancerous may differ from their healthy neighbors in only a few subtle ways. A central challenge in the treatment of cancer and many other diseases is […]
August 20, 2020

The Gut Microbiome Changes Shortly Before Death in Centenarians

Extremely old people have such high mortality rates that studies such as this one here become practical, answering the question of how the gut microbiome changes in the final decline into death. It is well established that the gut microbiome is influential on health, and undergoes detrimental changes across the […]
August 20, 2020

Immunotherapy extends survival in mouse model of hard-to-treat breast cancer

Immunotherapies for cancer — treatments that prime the immune system to attack tumors — are valuable weapons in the anti-cancer arsenal. But some cancers are more difficult to target with this strategy than others. Today, scientists report a new type of immunotherapy that dramatically extends the survival of mice that […]
August 20, 2020

Researchers find method to regrow cartilage in the joints

Researchers at the Stanford University School of Medicine have discovered a way to regenerate, in mice and human tissue, the cushion of cartilage found in joints. Loss of this slippery and shock-absorbing tissue layer, called articular cartilage, is responsible for many cases of joint pain and arthritis, which afflicts more than 55 […]
August 20, 2020

Researchers find way to speed up nerve regrowth for trauma patients

Electrical stimulation a week before surgery causes nerves to regenerate three to five times faster, leading to better outcomes. A University of Alberta researcher has found a treatment that increases the speed of nerve regeneration by three to five times, leading to much better outcomes for trauma surgery patients. “We […]
August 20, 2020

Genetic background may affect adaptions to aging

How we adapt to aging late in life may be genetically influenced, according to a study led by a psychologist at the University of California, Riverside. The research, published in Aging Cell, has implications for how epigenetic factors related to aging. Epigenesis is a process in which chemicals attached to DNA […]
August 20, 2020

Iron-mediated cancer cell activity: a new regulation mechanism

CNRS researchers at the Institut Curie have recently shown that cancer cells use a membrane protein that has been known for several decades to internalise iron. Published in Nature Chemistry (August 3rd, 2020), this work shows that the absorbed iron allows cancer cells to acquire metastatic properties. Biologists knew CD44 […]
August 19, 2020

Reducing LDL Cholesterol is the Wrong Target for Cardiovascular Disease

When people say “cardiovascular disease” in the context of blood cholesterol, they mean atherosclerosis. This is the name given to the build up of fatty deposits that narrow and weaken blood vessels, leading to heart failure and ultimately some form of disabling or fatal rupture – a stroke or heart […]