Related Science News – Page 192 – Innovita Research

Related Science News

March 6, 2020

AI reveals differences in appearance of cancer tissue between racial populations

Scientists better predict recurrence of prostate cancer for black patients, according to new study; land $3.2 million in federal grants to explore racial bias in cancer diagnosis using Artificial Intelligence, computational imaging. Scientists at Case Western Reserve University are using Artificial Intelligence (AI) to reveal apparent cellular distinctions between black […]
March 5, 2020

Gene therapy shows promise in tackling common cause of childhood blindness

The results of a first-in-human clinical trial of gene therapy to treat a common cause of genetic blindness have shown partial reversal of sight loss in some patients. X-linked retinitis pigmentosa, caused by mutations in RPGR gene, is the most common cause of blindness in young people. The inherited mutations […]
March 5, 2020

USask researchers test out new exercises to help FORTIFY Bones

A new study has a group of University of Saskatchewan (USask) researchers taking a look at how high intensity resistance exercises can help adults over the age of 50 who are suffering with bone issues such as osteoporosis. “Ideally, you don’t want someone to be crippled the last 10 or […]
March 5, 2020

Chemotherapy rewires a novel resistance-promoting signaling pathway in ovarian cancer

Researchers from Karolinska Institutet along with clinicians from the Karolinska University Hospital have discovered a new molecular mechanism of cell oncogenic signaling switch, which is induced by platinum chemotherapy and contributes to treatment resistance in ovarian cancer. Even with the continuous development of new anti-cancer treatments, chemotherapy is used as […]
March 5, 2020

Scientists explore how the brain trains muscles to move

But research into the neurological process of learning how to move suggests that it might be more accurate to say “mindful practice makes perfect.” This may not sound revolutionary to anyone who’s ever shot a free throw like LeBron or knocked a golf ball like Nicklaus. Star athletes understand that […]
March 5, 2020

People with MS are living longer. How does neurodegeneration in these patients change as they age?

Neurodegeneration results from a number of neurological conditions affecting older adults, including Alzheimer’s disease and Parkinson’s disease. Treating such diseases is challenging enough, but in recent years, the increased longevity of patients with multiple sclerosis, which also causes neurodegeneration and brain atrophy, has highlighted the need to understand the differences […]
March 4, 2020

Modified tuberculosis vaccine as a therapy for cancer of the bladder

The human immune system can recognize and eliminate not only germs but also cancer cells. This is why treatments with weakened germs can help the immune system in its fight against cancer. Researchers at the Max Planck Institute for Infection Biology in Berlin have genetically modified the tuberculosis vaccine BCG […]
March 4, 2020

Boosting energy levels within damaged nerves may help them heal

NIH-funded project in mice provides insights into why nerves fail to regrow following injury. When the spinal cord is injured, the damaged nerve fibers — called axons — are normally incapable of regrowth, leading to permanent loss of function. Considerable research has been done to find ways to promote the […]
March 4, 2020

Illuminating the Athletic Aorta

It’s long been known that endurance athletes have larger hearts on average than the rest of the population and that cardiac enlargement is a healthy adaptation to exercise. But what wasn’t known until now was whether the aorta—the main artery leaving the heart and supplying the body with oxygenated blood—followed […]
March 3, 2020

Scientists discover new “Jekyll and Hyde” immune cell

Scientists from Trinity have identified a rare, new cell in the immune system with “Jekyll and Hyde properties”. These cells play a key protective role in immunity to infection but – if unregulated – also mediate tissue damage in autoimmune disorders. The findings should help us design more effective vaccines […]
March 3, 2020

Presence of Staph Bacteria in Skin Microbiome Promotes Netherton Syndrome Inflammation

Netherton syndrome, a rare skin disease caused by a single genetic mutation, is exacerbated by the presence of two common Staphylococcal bacteria living on human skin, one of which was previously thought to only offer protective properties, report University of California San Diego School of Medicine researchers. “Our study shows how closely […]
March 3, 2020

Research identifies how new cancer treatments can activate tuberculosis infection

Researchers at the University of Southampton have identified how new checkpoint inhibitor treatments for cancer can activate tuberculosis in some patients. Immune therapies for cancer are transforming treatment by activating the body’s immune cells to fight off cancer. Immune checkpoints are part of the human body’s immune system that prevent […]
March 3, 2020

Scientists show drug may greatly improve cancer immunotherapy success

A study led by the University of Southampton, funded by Cancer Research UK, has shown a new drug – originally developed to tackle the scarring of organ tissue – could help to significantly improve the success rate of cancer immunotherapy treatment. Scientists have shown in mouse cancers, that GKT137831 (Setanaxib) […]
March 3, 2020

Brain immune cells, neurodegeneration differ in males, females

Immune cell activity in the brain differs between males and females in ways that may explain why some neurodegenerative diseases affect the sexes differently, according to a new study from Weill Cornell Medicine scientists. Dr. Li Gan, the Burton P. and Judith B. Resnick Distinguished Professor in Neurodegenerative Diseases in […]
March 3, 2020

Egg stem cells do not exist, new study shows

Researchers at Karolinska Institutet in Sweden have analysed all cell types in the human ovary and found that the hotly debated so-called egg stem cells do not exist. The results, published in Nature Communications, open the way for research on improved methods of treating involuntary childlessness. The researchers used single-cell […]
March 3, 2020

Blood test method may predict Alzheimer’s protein deposits in brain

Researchers report an advance in the development of a blood test that could help detect pathological Alzheimer’s disease in people who are showing signs of dementia. This approach could be less invasive and less costly than current brain imaging and spinal fluid tests. The blood test detects the abnormal accumulation […]
March 3, 2020

New Blood Test Could Make Alzheimer’s Diagnosis Easier Than Ever

A simple blood test may soon be able to diagnose patients with two common forms of dementia – Alzheimer’s disease and frontotemporal dementia (FTD) – and tell the two apart. Researchers at UC San Francisco analyzed the blood test in more than 300 patients and say they hope to see […]
March 3, 2020

Study: AI improves radiologists’ readings of mammograms

Machine-learning algorithms could help improve the accuracy of breast cancer screenings when used in combination with assessments from radiologists, according to a study published in JAMA Network Open. The study was based on results from the Digital Mammography (DM) DREAM Challenge, a crowd-sourced competition to engage an international scientific community to assess whether […]
March 3, 2020

Study underscores importance of molecular highways for organ health

Turns out, even your cells hate traffic jams. In order for cells to function properly, they need to be able to coordinate traffic within their walls and let information flow in and out. Inside a cell, molecules, organelles and information travel along microtubules, which work like highways or conveyor belts. […]
March 2, 2020

New chemo combo shows promise versus pancreatic cancer

The targeted drug palbociclib may boost the effectiveness of chemotherapy in pancreatic cancer if the two treatments are given in the right sequence, according to new preclinical research by Weill Cornell Medicine and NewYork-Presbyterian investigators. The study, published in Cancer Cell, found that palbociclib may stop pancreatic cancer cells from repairing […]
March 2, 2020

Stable conditions during cell division

Errors during cell division can trigger the development of cancer. No wonder that this central process is controlled by multiple regulators and guards. Alex Bird's research group at the Max Planck Institute of Molecular Physiology has discovered a hitherto unknown key player and how it provides the necessary stability to […]
March 2, 2020

New Cas9 variant makes genome editing even more precise

CRISPR-Cas9 has revolutionized the field of genetics by its ability to cut DNA at defined target sites. Researchers are using the Cas9 enzyme to specifically switch off genes, or insert new DNA fragments into the genome. But no matter how specific the Cas9 enzyme is – sometimes it cuts where […]
March 2, 2020

A weak heart also damages the brain

If the heart pumps too little blood into the body, the brain is usually not adequately supplied with oxygen. Until now, however, it was unclear how this affects brain structure. Researchers at the Max Planck Institute for Human Cognitive and Brain Sciences together with colleagues from the Leipzig Heart Clinic, […]
March 2, 2020

An Epigenetic Clock for Skeletal Muscle

Epigenetic clocks are multiplying year by year. Each is a weighted algorithmic combination of the status of various methylation sites on the genome, built by analyzing the epigenome of many different people at different ages in order to arrive at correlations with chronological age, or, more usefully, with metrics such as mortality risk that reflect biological […]
March 2, 2020

Length of pregnancy alters the child's DNA

Researchers from Karolinska Institutet led by Professor Erik Melén have together with an international team mapped the relationship between the length of pregnancy and chemical DNA changes in more than 6,000 newborn babies. For each week's longer pregnancy, DNA methylation changes in thousands of genes were detected in the umbilical […]