Related Science News – Page 113 – Innovita Research

Related Science News

June 22, 2021

Targeted Therapy for ‘Undruggable’ Lung Cancer Stems from Decades of UCSF Research

Over the past two decades, targeted cancer therapies have changed the prognosis for thousands of patients. By targeting the specific genetic mutation behind a patient’s cancer, these therapies have enabled increasing numbers of patients to experience fewer toxic side effects and, often, live free of disease following their treatment. But […]
June 22, 2021

Nrf2: The Custodian Regulating Oxidative Stress and Immunity Against Acrylamide Toxicity

Acrylamide, which is extensively used in industries, causes peripheral neuropathy or encephalopathy. Now, scientists from Japan examined the response against oxidative stress in acrylamide-induced neurotoxicity and found that nuclear factor erythroid 2-related factor 2 (Nrf2), a master regulator of the immune system and response to oxidative stress, was at the […]
June 22, 2021

Gene edits quell rhythm problem from heart stem-cell grafts

Regenerative medicine researchers have made progress toward overcoming a seemingly intractable obstacle to stem cell-derived heart cell transplantation for repairing damaged heart muscle. Their approach is a significant advance toward making heart cell transplants a potential reality for patients with cardiac disease. Their findings were presented at the International Society for Stem […]
June 22, 2021

Asymptomatic pertussis more common than believed

New study challenges long-standing assumptions about disease severity in infants. Pertussis, also known as whooping cough, remains a significant cause of death in infants and young children around the world and, despite global vaccination programs, many countries are experiencing a resurgence of this highly contagious disease. A new study by Boston […]
June 21, 2021

How Cells “Read” Artificial Ingredients Tossed into Genetic Recipe

If the genome is the recipe of life, base pairs are the individual ingredients listed. These chemical structures form DNA, and every living organism on Earth has just four. The specific arrangements of these four base pairs — A, T, C, G — make us who and what we are. […]
June 21, 2021

Gut to brain: nerve cells detect what we eat

The gut and the brain communicate with each other in order to adapt satiety and blood sugar levels during food consumption. The vagus nerve is an important communicator between these two organs. Researchers from the Max Planck Institute for Metabolism Research in Cologne, the Cluster of Excellence for Ageing Research […]
June 21, 2021

Bio-inspired hydrogel protects the heart from post-op adhesions

A hydrogel that forms a barrier to keep heart tissue from adhering to surrounding tissue after surgery was developed and successfully tested in rodents by a team of University of California San Diego researchers. The team of engineers, scientists and physicians also conducted a pilot study on porcine hearts, with […]
June 21, 2021

Start-stop system of hunting immune cells

Neutrophils belong to the first responders of our immune system. They circulate in our bodies and hunt in infected tissues to ingest, kill, and digest harmful pathogens. To become such effective killers in the very complex situation of an inflamed tissue, they work together as a collective. They release chemical […]
June 21, 2021

First months decisive for immune system development

Many diseases caused by a dysregulated immune system, such as allergies, asthma and autoimmunity, can be traced back to events in the first few months after birth. To date, the mechanisms behind the development of the immune system have not been fully understood. Now, researchers at Karolinska Institutet show a […]
June 21, 2021

Unraveling the origin of Alzheimer’s disease

Case Western Reserve University researchers studying prions—misfolded proteins that cause lethal incurable diseases—have identified for the first time surface features of human prions responsible for their replication in the brain. The ultimate goal of the research is to help design a strategy to stop prion disease in humans—and, ultimately, to […]
June 21, 2021

Studying the preteen brain for insights into mental health disorders

University of Utah Health scientists and collaborators with the Adolescent Brain Cognitive Development (ABCD) Consortium have developed a rich resource for studying how the brain changes and matures during adolescence: a collection of functional MRI scans revealed patterns of brain activity in more than 6,000 9- and 10-year-old children. The […]
June 20, 2021

The Longest-Running Evolution Experiment

Evolution is hardly predictable. But it works. And works so well, that this efficiency of evolving is often underestimated by a large part of scientific community. Quick fact: in less than two weeks bacteria can evolve to resist antibiotics thousands of times stronger than what would have killed them at […]
June 20, 2021

New study on brain cooling turns treatment advice on its head

A large international study on the effects of cooling the brain after a cardiac arrest shows that contrary to current treatment recommendations, it doesn’t actually improve survival or recovery. The study, published in the New England Journal of Medicine, suggests that a less intensive approach to temperature control in these patients […]
June 19, 2021

Electroconvulsive therapy: Peeling back the mystery

Christina often struggled to get through the average day. A former teacher diagnosed with treatment-resistant depression – along with OCD, bipolar disorder and Complex Post-Traumatic Stress Disorder (CPTSD) – was unable to work. At one point she was taking almost 60 different pills per day, with little to no effect […]
June 18, 2021

Intermittent fasting ‘no magic bullet for weight loss’ says new study

New research published challenges a popular belief that intermittent fasting diets such as alternate day fasting or the ‘5:2’ are the most effective ways to lose weight. Over recent years, diets that see people fast on a few days each week have increased in popularity, reinforced by images of people’s […]
June 17, 2021

Several persistent chemicals were found in fetal organs

Researchers at Karolinska Institutet found industrial chemicals in the organs of fetuses conceived decades after many countries had banned the substances. In a study published in the journal Chemosphere, the researchers urge decision-makers to consider the combined impact of the mix of chemicals that accumulate in people and nature. “These […]
June 17, 2021

Mitochondrial ribosome assembly in 3D

In a study published in Nature Communications, researchers at Karolinska Institutet provide insight into the sequence of events leading to the formation of functional mitoribosomes and sheds light on the mechanism of action of nine mitoribosome assembly factors involved in this process. The results may help yield novel opportunities for […]
June 17, 2021

Top U.S. cancer centers call for urgent action to get cancer-preventing HPV vaccination back on track

Case Comprehensive Cancer Center, a partnership of Case Western Reserve University, University Hospitals and Cleveland Clinic, has joined with 71 other National Cancer Institute (NCI)-designated cancer centers and partner organizations to issue a joint statement urging the nation’s physicians, parents and young adults to get the human papillomavirus (HPV) vaccination back on […]
June 17, 2021

Scientists unravel the function of a sight-saving growth factor

Researchers at the National Eye Institute (NEI) have determined how certain short protein fragments, called peptides, can protect neuronal cells found in the light-sensing retina layer at the back of the eye. The peptides might someday be used to treat degenerative retinal diseases, such as age-related macular degeneration (AMD). The […]
June 17, 2021

Study sheds light on treatment options for devastating childhood brain cancer

Medulloblastoma is a rare but devastating childhood brain cancer. This cancer can spread through the spinal fluid and be deposited elsewhere in the brain or spine. Radiation therapy to the whole brain and spine followed by an extra radiation dose to the back of the brain prevents this spread and […]
June 17, 2021

Immune system protein may defend against deadly intestinal disease in babies

The intestinal disease necrotizing enterocolitis is a leading cause of death among premature infants born in the U.S. and across the globe. Characterized by excessive inflammation that can cause tissue decay in the bowels, the disease provides a pathway for infectious and deadly bacteria to enter the bloodstream. Despite four […]
June 17, 2021

Black and White Women Have Same Mutations Linked to Breast Cancer Risk

The prevalence of genetic mutations associated with breast cancer in Black and white women is the same, according to a new JAMA Oncology study of nearly 30,000 patients led by researchers in the Basser Center for BRCA at the Abramson Cancer Center. About five percent of both Black and white women have a genetic mutation […]
June 17, 2021

Sickle cell advance incorporates Rice lab’s tech

A Rice University professor involved in the search for a way to treat and perhaps cure sickle cell disease is available to comment on a major advance revealed today in Science Translational Medicine. Rice University bioengineer Gang Bao is a pioneer in sickle cell research and a co-author of the breakthrough study released led […]
June 17, 2021

Digital Breast Tomosynthesis Offers Modest Benefits over Standard Mammography

According to the Centers for Disease Control and Prevention, breast cancer ranks as the most prevalent cancer among American women. For over 40 years, mammography was the standard of care for breast cancer screening and detection but recently the popularity and use of digital breast tomosynthesis (DBT), or 3D mammography, […]
June 16, 2021

Those breakfast foods are fortified for a reason

Adults who skip breakfast are likely to miss out on key nutrients that are most abundant in the foods that make up morning meals, a new study suggests. An analysis of data on more than 30,000 American adults showed that skipping breakfast – and missing out on the calcium in […]