Related Science News – Page 96 – Innovita Research

Related Science News

November 10, 2020

Researcher narrows time window for administering specific treatment to infants with Krabbe disease

A team of University at Buffalo researchers have published a paper in Nature Communications that is helping to define the best time to give specific treatment to infants born with Krabbe disease (KD). This treatment has been found to prolong life for these infants, for as long as a few […]
November 10, 2020

A more abundant hormone to treat atrial fibrillation

Calcitonin, a well-known thyroid hormone that helps regulate bone mass and collagen production, is also produced by cells in the heart, researchers in Canada, the U.S., the U.K. and Australia have found. Published in Nature, their breakthrough promises to aid in developing new treatments for people with atrial fibrillation (AF), a common […]
November 10, 2020

Shifts in water temperatures affect eating habits of larval tuna at critical life stage, study finds

Small shifts in ocean temperature can have significant effects on the eating habits of blackfin tuna during the larval stage of development when finding food and growing quickly are critical to long-term survival, a new study from Oregon State University researchers has found. In a year of warmer water conditions, larval […]
November 10, 2020

Predicting Heart Disease: How Common Risk Factors Measure up in Individuals with Obesity

The standard approach of assessing long-term risk for atherosclerotic cardiovascular disease (ASCVD) works just as well for patients who are overweight as they do for patients at an optimal weight, according to a new study in JAMA Network Open. Led by Rohan Khera, MD, MS, an assistant professor of cardiovascular medicine at […]
November 9, 2020

Diet and lifestyle during pregnancy linked to modifications in infants’ DNA

A new study has shown pregnant women with obesity could reduce the health risks for their infants through improved diet and more physical activity. Research published in the journal PLosMed investigates the impact of high glucose in mothers with gestational diabetes mellitus (GDM) and changes to infants DNA. GDM is […]
November 9, 2020

Researchers show how to target a 'shape-shifting' protein in Alzheimer’s disease

A new study suggests that it is possible to design drugs that can target a type of shape-shifting protein involved in Alzheimer’s disease, which was previously thought to be undruggable. A team of researchers, led by the University of Cambridge, have identified a new mechanism of targeting amyloid-beta, a protein […]
November 9, 2020

Technique to regenerate the optic nerve offers hope for future glaucoma treatment

Scientists have used gene therapy to regenerate damaged nerve fibres in the eye, in a discovery that could aid the development of new treatments for glaucoma, one of the leading causes of blindness worldwide. Axons – nerve fibres – in the adult central nervous system (CNS) do not normally regenerate […]
November 9, 2020

Genes that shift butterfly wing colors identified

Cornell researchers have identified three genes responsible for changing the color of common buckeye butterfly wings, depending on what time of year the egg hatches and larvae develop. If the larvae develop early in the year, when days are shorter and colder, the butterflies (Junonia coenia) reach maturity in summer with […]
November 9, 2020

Effective new approach for treating people affected by diabetic eye disease

A new Liverpool led study, published in Diabetologia, presents the results of the largest clinical trial for diabetic retinopathy. The study highlights a new approach that could transform diabetic eye screening around the world that also has a significant cost saving for the NHS. The number of people living with diabetes […]
November 9, 2020

Primordial shapeshifters

It's the holy grail of synthetic biologists: creating a living cell from scratch. So far they’ve managed to make simple prototypes—essentially tiny fat balloons with a soup of genetic material inside, capable of reading genetic code, producing proteins, and transporting molecules around. Yet these artificial blobs lack an essential feature […]
November 9, 2020

MU Researchers Identify how Night-Shift Work Causes Internal Clock Confusion in Body

Night-shift workers face an increased risk of obesity and diabetes, but the underlying reason for that has been a mystery. Now, University of Missouri School of Medicine researchers have found a potential cause for metabolic changes during night-shift work that creates confusion between cells in the body and the central clock in […]
November 8, 2020

Model could improve design of vaccines, immunotherapies

The body's immune system defeats diseases by sensing foreign invaders, such as bacteria or viruses, then mounting a response against them. But how immune cell receptors work together to sense multiple molecules and make these decisions remained a mystery. Now, researchers at the Pritzker School of Molecular Engineering at the University […]
November 7, 2020

Drug Screen in 3-D Cell Culture Identifies Promising Lead Against Bladder Cancer Subtype

Researchers at the University of Michigan Rogel Cancer Center have identified a promising targeted therapy against the basal subtype of bladder cancer by screening 3-D cell cultures. MEK inhibitors showed the strongest response against the basal molecular subtype, the research group reported in Oncotarget. “It’s becoming more and more clear that […]
November 7, 2020

The gut trains the immune system to protect the brain

Gut-trained immune cells at CNS borders guard against meningitis and other infections. The membranes surrounding our brains are in a never-ending battle against deadly infections, as germs constantly try to elude watchful immune cells and sneak past a special protective barrier called the meninges. In a study involving mice and […]
November 6, 2020

Blood cell mutations confound prostate cancer liquid biopsy

Unrelated mutations, when present in the blood, can lead to false positive results in men with advanced prostate cancer who are undergoing liquid biopsies.  Such tests, which look for variants in the cell-free DNA that tumors shed into the blood plasma, help determine suitable treatment options. “You can actually measure […]
November 6, 2020

Western diet impairs odor-related learning and olfactory memory in mice

Problems with the sense of smell appear to be an early indicator of cognitive decline in people with type 2 diabetes. However, it’s unknown whether factors such as diet and obesity play a role in who develops these symptoms. Now, researchers reporting in ACS Chemical Neuroscience found that mice fed a moderate-fat, […]
November 6, 2020

Climate Change Will Give Rise to More Cancers

Climate change will bring an acute toll worldwide, with rising temperatures, wildfires and poor air quality, accompanied by higher rates of cancer, especially lung, skin and gastrointestinal cancers, according to a new report from UC San Francisco. In an analysis of nearly five dozen published scientific papers, the researchers provided […]
November 5, 2020

Yale Scientists Identify New Genes Related to Congenital Hydrocephalus

When babies are born with congenital hydrocephalus (CH), a condition traditionally thought to be a result of a buildup of cerebrospinal fluid (CSF) in the brain, neurosurgeons normally treat the condition by surgically implanting a shunt that drains fluid from the brain into the abdomen. “This neurosurgical treatment can be […]
November 5, 2020

Big babies, little mothers: tsetse flies show extreme mothering

The tsetse fly is an exception to the almost universal law of nature that babies are born smaller than their mothers. In an article published in BioEssays, Drs Sinead English and Antoine Barreaux from the University of Bristol’s School of Biological Sciences, together with colleagues at the Liverpool School of Tropical Medicine, and the Universities of Greenwich, Stellenbosch and California […]
November 4, 2020

Goodnight… everything you would like to know about sleep, dreams, dreaming, and their disorders

Since an average human spends one-third of their life asleep, it is apparent that the quality of sleep has an important impact on the overall life quality. Sleep has restorative power and improves human brain functioning, in particular memory and attention. Sleepy people have problems with concentration and commit more […]
November 4, 2020

Laser technology to offer an instant analysis of cancerous brain tissue

Accuracy is everything when you’re studying and treating the brain. This is why scientists need very precise methods and tools to deal with various conditions such as brain cancer. Now scientists at the University of Waterloo took a significant step towards development of laser imaging technology, which could precisely guide […]
November 4, 2020

Scientists identify specific brain region and circuits controlling attention

The attentional control that organisms need to succeed in their goals comes from two abilities: the focus to ignore distractions and the discipline to curb impulses. A new study by MIT neuroscientists shows that these abilities are independent, but that the activity of norepinephrine-producing neurons in a single brain region, […]
November 4, 2020

Dopamine regulates synchronicity in the activity of striatal neurons

Researchers from Karolinska Institutet and the University of California have uncovered the role of a polysynaptic pathway that links cholinergic neurons together. The study was recently published in Nature Communications. Cholinergic neurons are instrumental in regulating activity in the Striatum. Their acetylcholine interacts with dopamine to create just the right […]
November 4, 2020

Spontaneous release of neurotransmitters in the brain identified as a culprit of developmental disorders in infants and children

Vanderbilt pharmacologists have reported the first evidence that aberrant spontaneous release of neurotransmitters in the brain can cause a range of severe intellectual and neurodevelopmental disorders in infants and children. Ege Kavalali, who holds the William Stokes Chair in Experimental Therapeutics and is acting chair of pharmacology, and postdoctoral scholar Baris […]
November 4, 2020

‘Fast’ MRI Detects Breast Cancers that 3-D Mammograms May Miss

Beth Reisboard, 76, was relieved in 2018 when she received the results from her annual mammogram: “Negative.” But her OB-GYN suggested she have a second screening. Reisboard has dense breasts, which means there are certain cancers that mammography may not be sensitive enough to detect. Surprised, Reisboard scheduled an appointment […]
November 4, 2020

Software for determining the 3D structure of proteins

A new software package aims to aid drug design and biomedical research by making it easy to construct 3D images of proteins and other molecules using one of the world’s most powerful microscopes. Amit Singer, professor of mathematics and the Program in Applied and Computational Mathematics, and his team are developing a package […]
November 4, 2020

Break it up: Polymer derived from material in shrimp’s shells could deliver anti-cancer drugs to tumor sites

Drug delivery is a recurring conundrum in cancer treatment. Scientists have developed many anti-cancer therapeutics. But those drugs often harm healthy tissues, and drugs can even break down in the bloodstream before reaching the tumor site. Anti-cancer drugs can last longer if dissolved in certain chemical solutions, but many come […]
November 3, 2020

Understanding mutations at different levels of the cell

Researchers working under ETH-Professor Emeritus Ruedi Aebersold have demonstrated how mutations in a gene influence the structure, function and interaction network of a protein complex. Their work plays a key foundation for personalised medicine. In the wake of proclaiming the “Age of the Genome” in the 1990s, scientists mapped the […]
November 3, 2020

New analysis method can lead to better cancer drugs

While proteins on the surface of cells are the targets for most drugs, refined methods are needed to analyse how these membrane proteins are organised. Researchers at Karolinska Institutet have developed a new DNA-based analytical method that could contribute to the development of future drugs for breast and other cancers. […]
November 3, 2020

Swipe right to help tackle brain disease

The app, dubbed NeuroSwipe, is a citizen science collaboration between students at the University’s National Software Academy and academics at the Cardiff University Brain Research Imaging Centre (CUBRIC). The app trains non-scientists to become experts at recognising brain scans that would be suitable for a scientific study, potentially saving researchers valuable […]