Related Science News – Page 62 – Innovita Research

Related Science News

December 11, 2020

Testing memory over four weeks could predict Alzheimer's disease risk

New research suggests testing people's memory over four weeks could identify who is at higher risk of developing Alzheimer's disease before it has developed. Importantly, the trial found testing people's ability to retain memories for longer time periods could predict this more accurately than classic memory tests, which test memory […]
December 11, 2020

New research identifies which T cells patrol the body

The blood is the main source of studies on the immune system, despite the fact that most diseases are combated by immune cells in the body’s tissues. A new study from Karolinska Institutet and the University of Pennsylvania has identified which immune cells patrol the human body’s tissues and circulate […]
December 11, 2020

Genetic differences important for Alzheimer's diagnosis

The two used methods for detecting amyloid pathology in Alzheimer's disease do not give unambiguous results, with the risk of incorrect or delayed care interventions. Now, researchers at Karolinska Institutet have found genetic explanations for the differences. The study is published in Molecular Psychiatry and may be important for more […]
December 11, 2020

Toxin provides clues to long-term effects of diarrhea caused by E. coli

For people in wealthy countries, diarrhea is usually nothing more than an uncomfortable inconvenience for a few days. But for a poor child in a developing country, repeated bouts of diarrhea can lead to serious health consequences such as malnutrition, stunted growth and cognitive deficits. Researchers at Washington University School […]
December 11, 2020

The Long Reach of Pandemics

Epidemics and pandemics are not equal-opportunity killers. Seen through the archaeological record, incomplete as it may be, these waves of death victimized the marginalized and most vulnerable populations wherever they struck. In the U.S., the COVID-19 pandemic appears to be no different, striking Indigenous, Black and Latinx communities at far […]
December 11, 2020

Using CRISPR, new technique makes it easy to map genetic networks

CRISPR-Cas9 makes it easy to knock out or tweak a single gene to determine its effect on an organism or cell, or even another gene. But what if you could perform several thousand experiments at once, using CRISPR to tweak every gene in the genome individually and quickly see the […]
December 10, 2020

News Releases News Topics Media Advisories University Statements Study: Memory deficits resulting from epigenetic changes in Alzheimer’s disease can be reversed

Memory loss associated with Alzheimer’s disease (AD) may be able to be restored by inhibiting certain enzymes involved in abnormal gene transcription, according to a preclinical study by researchers at the University at Buffalo. The findings could pave the way toward new treatments for Alzheimer’s disease. The paper will be […]
December 10, 2020

Making Memories

On a late summer day in 1953, a young man who would soon be known as patient H.M. underwent experimental surgery. In an attempt to treat his debilitating seizures, a surgeon removed portions of his brain, including part of a structure called the hippocampus. The seizures stopped. Unfortunately, for patient […]
December 10, 2020

Obesity and Cancer

Obesity has been linked to increased risk for over a dozen different types of cancer, as well as worse prognosis and survival. Over the years, scientists have identified obesity-related processes that drive tumour growth, such as metabolic changes and chronic inflammation, but a detailed understanding of the interplay between obesity […]
December 9, 2020

Scientists reveal genetic map of the human face

An international team of researchers has connected specific genetic regions which influence facial features. This means they can see the signals of normal facial features in the genome – but it is also hoped their work can shed light on craniofacial malformations such as cleft lip and palate. The findings […]
December 9, 2020

Multiple gene edits and computer simulations could help treat rare genetic diseases

The lab of Kris Saha at the University of Wisconsin–Madison has developed an innovative combination of gene-editing tools and computational simulations that can be used to develop new strategies for editing genes associated with genetic disorders. In proof-of-concept experiments, the lab’s researchers efficiently corrected multiple mutations responsible for a rare metabolic disorder, known […]
December 9, 2020

Cells optimized to produce antimicrobial agents

Big changes are taking place in the research laboratories at DTU Biosustain on Lyngby Campus—but it requires a microscope to spot them, as the changes are occurring in microorganisms such as the bacterium, Streptomyces.  The bacterium is known to produce antimicrobial agents. In the New Bioactive Compound Section, researchers are […]
December 9, 2020

Hidden structure found in essential metabolic machinery

In his first year of graduate school, Rice University biochemist Zachary Wright discovered something hidden inside a common piece of cellular machinery that’s essential for all higher-order life from yeast to humans. What Wright saw in 2015 — subcompartments inside organelles called peroxisomes — is described in a study published in Nature […]
December 9, 2020

Secret of how fish repair their hearts could help cardiac patients

The ability of certain fish to heal damage to their hearts could lead to new treatments for patients who have suffered heart attacks and may also help to unravel how the lifestyle of our parents and grandparents can affect our own heart health. The human heart cannot heal itself. After […]
December 8, 2020

Research could lead to step-change in NHS hearing aid provision

Cutting-edge research being led by the NIHR Manchester Biomedical Research Centre (BRC) and the University of Manchester, aimed at increasing adult hearing aid use, could make a dramatic change to people with hearing loss. The study ‘Follow-up and structured monitoring for adults offered an NHS hearing aid for the first […]
December 8, 2020

Magnetic bacteria as micropumps

ETH scientists use magnetic bacteria to control liquids at the micro-level. They are already thinking about using them in the human bloodstream for precision delivery of cancer drugs to a tumour. Cancer drugs have side effects, so for many years, scientists have been exploring ways to transport the active substances […]
December 8, 2020

Novel form of Alzheimer’s protein found in spinal fluid indicates stage of the disease

A novel form of an Alzheimer’s protein found in the fluid that surrounds the brain and spinal cord indicates what stage of the disease a person is in, and tracks with tangles of tau protein in the brain, according to a study from researchers at Washington University School of Medicine […]
December 8, 2020

Dynamic plants

Just like other organisms, plants must respond dynamically to a variety of cues over their lifetime. Going through different developmental stages, or altering their form in response to a drought or drastic temperature change requires altering which of their genes are expressed into proteins and when those processes occur. In […]
December 8, 2020

Hydrogel Could Open New Path for Glaucoma Treatment Without Drugs or Surgery

Researchers have developed a potential new treatment for the eye disease glaucoma that could replace daily eye drops and surgery with a twice-a-year injection to control the buildup of pressure in the eye. The researchers envision the injection being done as an office procedure that could be part of regular […]
December 8, 2020

Researchers develop rapid antibody generation technology

Using the same strain of yeast that ferments wine and makes dough rise, a team led by the University of California, Irvine and Harvard Medical School researchers has developed an in vitro technology that can rapidly hypermutate antibodies. The new technology generates antibodies faster than animal immune systems and better than […]
December 7, 2020

Colloidal silver – the snake oil of the XXIst century, or a miracle?

We live in a world that cultivates eternal youth. The pharmaceutical market is full of new, shiny, “revolutionary” products, which are meant to put us in good shape and give us a pristine, young appearance, and long life in well-shape. Advertisements scream of various supplements, vitamins, or syrups, supposed to […]
December 7, 2020

Down syndrome symposium highlights clinical, fundamental progress

Whether they are working with patients in clinical trials or with chromosomes in cell cultures, scientists and physicians in the Boston area and beyond are testing a wide variety of new ways to help people with Down syndrome. At the New England Down Syndrome Symposium, presented by the Alana Down […]
December 7, 2020

Brain activity and repetitive behaviour

“Civilization advances by extending the number of important operations which we can perform without thinking of them.” In this quote, the philosopher A. Whitehead underlines the importance of automated low-level tasks when performing a complex and repetitive task. Tying shoelaces, writing, walking… our mind is relieved from the elementary actions […]
December 7, 2020

Advancing Gene Editing With New CRISPR/Cas9 Variant

Using a new variant to repair DNA will improve both safety and effectiveness of the much-touted CRISPR-Cas9 tool in genetic research, Michigan Medicine researchers say. Those two key problems – safety and efficacy – are what continue to hold CRISPR-Cas9 gene targeting back from its full clinical potential, explains co-senior […]
December 7, 2020

New Alzheimer’s disease pathway discovered, providing earlier target for potential therapies

Researchers at the Case Western Reserve University School of Medicine have identified a new target in the development of Alzheimer’s disease (AD) that could lead to therapies focused on treating the neurodegenerative condition early in its progression. The discovery helps bolster a promising approach to AD research: finding and manipulating […]
December 7, 2020

Resistance Pulse

In recent years, targeted therapies have cemented their place as some of the most important tools in cancer treatment. These medicines are designed to block specific signals that tumour cells use to grow and spread, while at the same time leaving normal cells unharmed. Targeted therapies can significantly extend patients’ […]
December 7, 2020

UVA aims to improve sepsis treatment, save lives in Africa

Doctors at the University of Virginia School of Medicine are launching an ambitious effort in sub-Saharan Africa to target the dual scourges of sepsis and tuberculosis, a combination that kills up to half the people who contract it. UVA Health Drs. Scott Heysell, Christopher Moore and Tania Thomas are seeking to […]
December 7, 2020

A novel approach to Parkinson's disease

When scientists study the neuronal mechanisms responsible for neurodegenerative diseases like Parkinson’s, they can open the door to promising new approaches to treating those diseases with drugs. But when a person with Parkinson's dies, looking at their brain reveals little about the cells inside and offers only a glimpse into […]
December 5, 2020

New DNA modification ‘signature’ discovered in zebrafish

Researchers at the Garvan Institute of Medical Research have uncovered a new form of DNA modification in the genome of zebrafish, a vertebrate animal that shares an evolutionary ancestor with humans ~400 million years ago. Dr Ozren Bogdanovic and his team discovered that unusually high levels of DNA repeats of […]
December 5, 2020

Clinical guidance for two rare immune conditions revealed

An international study co-led by researchers at the Garvan Institute of Medical Research has provided new guidance for the clinical treatment of two rare inherited immune disorders. Researchers combined global data on the two conditions, caused by variants of the genes CD27 and CD70, and diagnosed mostly in children. Their study revealed that […]