Related Science News – Page 81 – Innovita Research

Related Science News

October 5, 2020

Don’t blame ‘beer belly’ on beer

In many people, ageing makes it harder to burn fat, which accumulates in the abdomen as a “beer belly.” Now, a team led by Christina Camell, an assistant professor in the Department of Biochemistry, Molecular Biology and Biophysics of the U of M Medical School and College of Biological Sciences, […]
October 5, 2020

Element in blood is part of stress response

A new study published in the journal Critical Care Explorations shows for the first time that part of the stress response in people and animals involves increasing the levels of a naturally circulating element in the blood. The discovery demonstrates a biological mechanism that rapidly responds to severe physiologic stress and […]
October 4, 2020

Scientists uncovered how biological cells get and maintain their shapes

Biological cells can be all kinds of shapes and sizes, even though they don’t have skeletons or other rigid structures to maintain that shape. Different forms help different types of cells accomplish different functions. How do they do that? Scientists at the Swiss Federal Institute of Technology in Zürich discovered […]
October 3, 2020

Difficulty learning new things may be one of the earliest signs of Alzheimer's

There is no cure for Alzheimer’s disease. And millions of people are going to get it, even though not everyone will hear the diagnosis. There are, however, some therapies that can slow down the progression of this neurodegenerative condition, but it has to be spotted early. Now scientists at the […]
October 2, 2020

Cancer researchers collaborate, target DNA damage repair pathways for cancer therapy

Cancer therapies that target specific molecular defects arising from mutations in tumor cells are currently the focus of much anticancer drug development. However, due to the absence of good targets and to the genetic variation in tumors, platinum-based chemotherapies are still the mainstay in the treatment of many cancers, including […]
October 2, 2020

How local forces deform the lipid membranes

ETH Zurich researchers have been able to show why biological cells can take on such an astonishing variety of shapes: it has to do with how the number and strength of local forces acting on the cell membrane from within. This knowledge feeds into the development of better minimal model […]
October 1, 2020

Stanford scientists solve secret of nerve cells marking a form of schizophrenia

When nerve cells aren’t busy exchanging information, they’re supposed to keep quiet. If they’re just popping off at random, like in a noisy classroom, it obscures the signals they’re supposed to be transmitting. But in the most common genetic cause of schizophrenia, it seems that nerve cells won’t shut up, Stanford […]
October 1, 2020

Cancer cells use nerve-cell tricks to spread from one organ to the next

Tumors come in many shapes and forms—curable or deadly, solid or liquid, lodged inside the brain, bone, or other tissues. One thing they all have in common, however, is a knack for molecular deceit. It is often by posing as normal cells, or by hijacking them, that cancer cells advance […]
October 1, 2020

The heat is on for building 3D artificial organ tissues

Bioengineers are devising a hot new technology to remotely control the positioning and timing of cell functions to build 3-dimensional, artificial, living tissues. The labs of Kelly Stevens at the UW Medicine Institute of Stem Cell and Regenerative Medicine in Seattle, and Jordan Miller at Rice University in Houston, are collaborating to develop bio-printed, organ-like tissues, […]
October 1, 2020

Penn Researchers Discover Potential Cause of Immunotherapy-Related Neurotoxicity, Chart Path Forward

New research has uncovered the previously unknown presence of CD19 — a B cell molecule targeted by chimeric antigen receptor (CAR) T cell immunotherapy to treat leukaemia, lymphoma, and multiple myeloma — in brain cells that protect the blood-brain barrier (BBB). This discovery may potentially be the cause for neurotoxicity […]
September 30, 2020

Persistent immune memory of COVID-19 found in recovered patient T cells

Oxford University researchers have found that natural infection with COVID-19 produces a robust T cell response, including inducing T cell ‘memory’ to potentially fight future infections. The results, published in Nature Immunology, are a joint effort from the Oxford COVID-19 immunology group, led by the Medical Research Council Human Immunology […]
September 30, 2020

Raised blood pressure and diabetes alter brain structure to slow thinking speed and memory

In a new study published neuroscientists at Oxford University have found that raised blood pressure and diabetes in mid-life alter brain structure to slow thinking speed and memory. Looking at results from 22,000 volunteers in the UK Biobank who underwent brain scanning, the scientists found that raised blood pressure and […]
September 30, 2020

Gene expression altered by direction of forces acting on cell

Tissues and cells in the human body are subjected to a constant push and pull – strained by other cells, blood pressure and fluid flow, to name a few. The type and direction of the force on a cell alters gene expression by stretching different regions of DNA, researchers at […]
September 30, 2020

New research sheds light on why tumour cells become resistant to chemotherapy

A team of University of Alberta researchers has identified a new mechanism through which tumour cells become resistant to chemotherapy—a discovery that could lead to better treatments for women with breast cancer. Michael Jewer, a post-doctoral researcher in the Faculty of Medicine & Dentistry, said that more than 20 per cent […]
September 30, 2020

Dementia Prediction

Harvard Medical School investigators based at Massachusetts General Hospital and Beth Israel Deaconess Medical Center have developed a machine learning-based sleep test that shows potential as a biomarker associated with unhealthy brain ageing, including processes leading to dementia. The findings, published in JAMA Network Open, may help clinicians identify patients who have […]
September 30, 2020

UM171 saves another life

In a world-first, a young man suffering from severe aplastic anaemia who could not be helped by standard treatments has been given a life-saving blood transplant with the made-in-Canada UM171 molecule. The procedure was done by a medical team at the Institute of Hemato-oncology and Cellular Therapy (iHOTC) of Maisonneuve-Rosemont […]
September 29, 2020

Spinal Cord Stimulation Reduces Pain and Motor Symptoms in Parkinson’s Disease Patients

A team of researchers in the United States and Japan reports that spinal cord stimulation (SCS) measurably decreased pain and reduced motor symptoms of Parkinson’s disease, both as a singular therapy and as a “salvage therapy” after deep brain stimulation (DBS) therapies were ineffective. Writing in the journal Bioelectronic Medicine, […]
September 29, 2020

Strong activation of anti-bacterial T cells linked to severe COVID-19

A type of anti-bacterial T cells, so-called MAIT cells, are strongly activated in people with moderate to severe COVID-19 disease, according to a study by researchers at Karolinska Institutet in Sweden that is published in the journal Science Immunology. The findings contribute to an increased understanding of how our immune […]
September 29, 2020

Mammogram device under development to use light, ultrasound to better screen patients for breast cancer

The University at Buffalo has received a four-year, $1.4 million grant from the National Institutes of Health (NIH) to develop a new, portable breast-imaging system that has the potential to better identify breast cancer. Called a dual scan mammoscope (DSM), the device combines light and ultrasound technology to better screen […]
September 29, 2020

Researchers uncover epigenetic drivers for Alzheimer’s disease

New findings suggest that late-onset Alzheimer’s Disease is driven by epigenetic changes—how and when certain genes are turned on and off—in the brain. Results were published in Nature Genetics. Research led by Raffaella Nativio, a former research associate of epigenetics, Shelley Berger, a professor of genetics, biology and cell and developmental diology and director […]
September 29, 2020

Women could conceive after ovarian tumours

Women receiving fertility-sparing surgery for treatment of borderline ovarian tumours were able to have children, a study from Karolinska Institutet in Sweden published in Fertility & Sterility shows. Natural fertility was preserved in most of them and only a small proportion required assisted reproductive treatment such as in vitro fertilization. […]
September 29, 2020

Cancer's Hidden Vulnerabilities

One of the biggest challenges to the development of medical treatments for cancer is the fact that there is no single kind of cancer. Cancers derive from many kinds of cells and tissues, and each has their own characteristics, behaviours, and susceptibilities to anti-cancer drugs. A treatment that works on […]
September 28, 2020

Insomnia, sleeping less than six hours may increase risk of cognitive impairment

Middle-aged adults who report symptoms of insomnia and are sleeping less than six hours a night may be at increased risk of cognitive impairment, according to a study by Penn State College of Medicine researchers. The results may help health care professionals understand which patients who report insomnia are at […]
September 28, 2020

Team IDs gene that drives ovarian cancer

High-grade serious ovarian carcinoma (HGSOC) is the fifth-leading cause of cancer-related deaths in women in the United States, yet little is known about the origins of this disease. Now, scientists at the College of Veterinary Medicine have collaborated on a study that pinpoints which specific genes drive – or delay […]
September 28, 2020

Study tracks how milk nutrients shape infant microbiome

A new study in mice helps explain why gut microbiomes of breastfed infants can differ greatly from those of formula-fed infants. The study, “Dietary Sphinganine Is Selectively Assimilated by Members of the Mammalian Gut Microbiome,” was published in the Journal of Lipid Research. The paper describes an innovative technique developed […]
September 28, 2020

Study finds that high levels of a growth factor increases risk for several cancers

A study of almost 400,000 British participants has identified a new link between raised levels of the growth factor IGF-1 and increased thyroid cancer risk and has confirmed associations with breast, prostate and colorectal cancer. This could lead to new preventative strategies, including diet and lifestyle interventions. IGF-1 (insulin-like growth […]
September 28, 2020

Architecture of the heart different between women and men and with age

Differences in the shape and texture of men and women's hearts could potentially explain why their risk of heart disease differs, according to research funded by the British Heart Foundation (BHF). The findings were presented at the European Society of Cardiology (ESC) Congress. Researchers at Queen Mary University of London, […]
September 28, 2020

Rare immune cells drive gut repair, but can tip toward cancer or fibrosis in inflammatory bowel disease

A team of scientists, led by King’s College London, have discovered an unexpected tissue reparative role for a rare immune cell type in the gut that could tip toward fibrosis or cancer if abnormal or impaired. The breakthrough, revealed in a paper published in Nature Materials, will have important implications for […]
September 28, 2020

Scientists Train Computers to Recognize Which Early Stage Breast Cancers Will Spread

About 1 in 5 new breast cancers are caught at their earliest stages, before they’ve spread from milk ducts into the surrounding breast tissue. But what doctors can’t currently predict with high confidence is which of these cancers — known as ductal carcinoma in situ (DCIS) or stage 0 breast cancer — […]
September 28, 2020

Nonalcoholic Fatty Liver Disease and Heart Failure: Is There a Connection?

Heart failure with preserved ejection fraction, or HFpEF, occurs when the contraction of the heart muscle is able to pump blood normally and subsequently has a preserved ejection fraction, but the heart chambers are too stiff to relax and fill properly. In the United States, HFpEF numbers are on the […]