Related Science News – Page 55 – Innovita Research

Related Science News

April 22, 2021

Cell-based method for the regeneration of myelin

Myelin is tremendously important for the correct and rapid transmission of electrical signals in the brain. This lipid-rich membrane, which wraps axons, is damaged in certain degenerative nerve disorders. Most of these are rare hereditary diseases with serious clinical courses. Generation of induced oligodendrocyte progenitor cells (iOPCs) from somatic fibroblasts […]
April 22, 2021

Targeted therapies thanks to biomedical informatics

The new “LOOP Zurich – Medical Research Center” promotes patient-focused therapies – for example in oncology and neuro-rehabilitation. To achieve its goals, the centre brings together specialist knowledge in the fields of biomedicine, clinical research and bioinformatics from the University of Zurich, ETH Zurich as well as Zurich’s four university […]
April 22, 2021

Working with local biotech, team tests drug that may prevent fatal COVID-19 lung damage

The University of Toronto has partnered with Markham, Ont.-based Edesa Biotech on laboratory studies of a drug that physicians are already using at Canadian hospitals in a clinical trial for some of their sickest patients. Researchers at the Temerty Faculty of Medicine are about to receive their first shipment of the drug, […]
April 22, 2021

Toward safer stem cell transplants

For cancer patients, the use of hematopoietic stem cell transplants can be a game-changer in terms of treatment and recovery. However, most people need to undergo a combination of chemotherapy and radiation before transplants become an option. A new article in Chemical & Engineering News, the weekly newsmagazine of the […]
April 22, 2021

Scientists find new point of access for targeting eating disorders and obesity

Scientists have identified a potential drug target for treating obesity and eating disorders such as anorexia nervosa, a condition for which no therapeutics are currently available. In a new study scheduled to publish in Science Translational Medicine, a team of researchers from the University of Michigan and Vanderbilt University pinpoints […]
April 22, 2021

For Scleroderma, Algorithm Helps Better Screen for Fatal Complication

Screening for a sometimes fatal condition among patients with a rare autoimmune disease could soon – thanks to a computer algorithm – become even more accurate. Researchers at Michigan Medicine found that an internet application improved their ability to spot pulmonary arterial hypertension in patients with systemic sclerosis, or scleroderma. […]
April 22, 2021

Optical technology from TAU can make an immediate melanoma diagnosis

An innovative optical technology that can distinguish between different types of skin cancer melanoma has been developed in the laboratory of Professor Abraham Katzir of the Raymond and Beverly Sackler Faculty of Exact Sciences at Tel Aviv University. The method, which is rapid, non-invasive, and painless, was tried successfully on about one hundred patients […]
April 22, 2021

Researchers identify proteins that cause intestinal disease

Researchers from Tel Aviv University (TAU) have created an artificial intelligence platform that can identify the specific proteins that allow bacteria to infect the intestines. The platform paves the way for the creation of smart drugs that can neutralize the proteins and prevent disease, eliminating the use of antibiotics. Participating in the […]
April 22, 2021

Micro-molded ‘ice cube tray’ scaffold is next step in returning sight to injured retinas

Tens of millions of people worldwide are affected by diseases like macular degeneration or have had accidents that permanently damage the light-sensitive photoreceptors within their retinas that enable vision. The human body is not capable of regenerating those photoreceptors, but new advances by medical researchers and engineers at the University […]
April 22, 2021

FSU researcher awarded $2.2M NIH grant to study impact of Alzheimer’s disease on sleep-related brain function

A Florida State University researcher has been awarded a $2.2 million grant from the National Institutes of Health to study sleep-related brain function in Alzheimer’s disease, a progressive disorder that affects memory and behaviour in millions of Americans. Assistant Professor of Psychology and Neuroscience Aaron Wilber will receive the grant, awarded […]
April 22, 2021

First-of-its-kind study links wildfire smoke to skin disease

Wildfire smoke can trigger a host of respiratory and cardiovascular symptoms, ranging from a runny nose and cough to a potentially life-threatening heart attack or stroke. A new study suggests that the dangers posed by wildfire smoke may also extend to the largest organ in the human body and our […]
April 22, 2021

Gut bacteria "talk" to horse's cells to improve their athletic performance

Study linking gut bacteria to more efficient energy generation in the cells of horses paves the way for dietary supplements that enhance their performance. A horse's gut microbiome communicates with its host by sending chemical signals to its cells, which has the effect of helping the horse to extend its […]
April 21, 2021

Cancer cells soften as they metastasize, study suggests

When cancer cells metastasize, they often travel in the bloodstream to a remote tissue or organ, where they then escape by squeezing through the blood vessel wall and entering the site of metastasis. A study from MIT now shows that tumor cells become much softer as they undergo this process. […]
April 21, 2021

Light up your mind: A novel light-based treatment for neurodegenerative diseases

Researchers review growing knowledge on the methods and applications of light therapy in treating neurodegenerative diseases. A lot about the human brain and its intricacies continue to remain a mystery. With the advancement of neurobiology, the pathogenesis of several neurodegenerative diseases (ND) has been uncovered to a certain extent along […]
April 21, 2021

Epidural use at birth not linked to autism risk, study finds

Having an epidural during childbirth is not associated with a greater risk of autism in the child, according to a study led by researchers at the Stanford University School of Medicine and the University of Manitoba. The study, which was published online in JAMA Pediatrics, helps resolve questions raised by an […]
April 21, 2021

New Urine-Based Test Holds Promise for Detecting Aggressive Prostate Cancer

Researchers at the University of Michigan Rogel Cancer Center have developed a new urine-based, multi-biomarker test to detect aggressive prostate cancer that performed better than existing biomarker tests in initial preclinical evaluations. The Urine Prostate Seq test, or UPSeq for short, uses next-generation genomic sequencing to analyze urine collected from men following a digital […]
April 21, 2021

Penn Researchers Uncover Link Between Racial, Gender and Socioeconomic Factors and Likelihood of Getting Proven Treatment for Diabetes

A new study from researchers at the Perelman School of Medicine at the University of Pennsylvania found significant disparities in the use of sodium-glucose cotransporter 2 (SGLT2) inhibitors, a class of drugs proven to treat type 2 diabetes, with usage remaining low with Black, Asian, and lower-income groups despite an […]
April 21, 2021

Mysterious “Nuclear Speckle” Structures Inside Cells Enhance Gene Activity, May Help Block Cancers

A team led by scientists at the Perelman School of Medicine at the University of Pennsylvania has illuminated the functions of mysterious structures in cells called “nuclear speckles,” showing that they can work in partnership with a key protein to enhance the activities of specific sets of genes. The discovery, […]
April 21, 2021

The immune link between a leaky blood-brain barrier and schizophrenia

Like a stern bodyguard for the central nervous system, the blood-brain barrier keeps out anything that could lead to disease and dangerous inflammation—at least when all is functioning normally. That may not be the case in people with schizophrenia and other mental disorders, suggest new findings from a team led […]
April 21, 2021

Improving drug efficacy against prostate cancer and related bone growths

Published in the Advanced Functional Materials, University of Minnesota researcher Hongbo Pang led a cross-institutional study on improving the efficacy of nucleotide-based drugs against prostate cancer and bone metastasis. In this study, Pang and his research team looked at whether liposomes, when integrated with the iRGD peptide, will help concentrate antisense oligonucleotides […]
April 21, 2021

Nutrient compound shows promise for halting mother-to-fetus Zika transmission

Before COVID-19, there was another public health crisis that captured headlines around the world: the Zika virus outbreak of 2015-16, which became an epidemic as it spread through Brazil and the Americas. The mosquito-borne virus was perhaps best known for causing significant birth defects, most prominently microcephaly, which can cause an […]
April 21, 2021

Nicotinamide Riboside Supplementation Beginning in Mid-Life Slows Osteoporosis in Mice

In today's open access paper, researchers report that long-term supplementation with nicotinamide riboside in mice, starting from mid-life and continuing into old age, slows the pace of osteoporosis. The extracellular matrix of bone tissue is constantly remodeled over time, broken down by osteoclasts and built up by osteoblasts. Osteoporosis is […]
April 20, 2021

Distinct Parkinson’s Disease Symptoms Tied to Different Brain Pathways

Identification of neural circuits clarifies motor vs. cognitive symptoms, aiding efforts to improve treatments. Parkinson’s disease (PD) is well known as a debilitating disease that gradually worsens over time. Although the disease’s progression has been largely tied to the loss of motor functions, non-motor symptoms, including the loss of cognitive […]
April 20, 2021

New Blueprint of Brain Connections Reveals Extensive Reach of Central Regulator

Map of basal ganglia connectivity uncovers key links with implications for range of disorders. Thousands of our daily activities, from making coffee to taking a walk to saying hello to a neighbor, are made possible through an ancient collection of brain structures tucked away near the center of the cranium. […]
April 20, 2021

Understudied Mutations Have Big Impact on Gene Expression

Variable number tandem repeats modulate genes associated with Alzheimer’s disease, obesity, cancer and other conditions. An international team of researchers led by computer scientists at the University of California San Diego have identified 163 variable number tandem repeats (VNTRs) that actively regulate gene expression. In a paper published in Nature […]
April 20, 2021

How Brain Tumors Turn Immune Cells into Cancer-Growing Hostages

Brain tumors known as glioblastomas are among the most aggressive and malevolent forms of cancer. Median survival time without treatment is just nine months; with standard of care surgery and chemoradiation, it’s 15 to 16 months. Patients rarely survive more than a few years. In only a very small subset […]
April 20, 2021

Study links prenatal phthalate exposure to altered information processing in infants

Exposure to phthalates, a class of chemicals widely used in packaging and consumer products, is known to interfere with normal hormone function and development in human and animal studies. Now researchers have found evidence linking pregnant women’s exposure to phthalates to altered cognitive outcomes in their infants. Most of the […]
April 20, 2021

New genetic clues point to new treatments for ‘silent’ stroke

Scientists have identified new genetic clues in people who have had small and often apparently ‘silent’ strokes that are difficult to treat and a major cause of vascular dementia, according to research led by the University of Cambridge and published in The Lancet Neurology. Researchers discovered changes to 12 genetic regions […]
April 20, 2021

Gene therapy technique shows potential for repairing damage caused by glaucoma and dementia

Scientists at the University of Cambridge have shown in animal studies that gene therapy may help repair some of the damage caused in chronic neurodegenerative conditions such as glaucoma and dementia. Their approach demonstrates the potential effectiveness of gene therapy in polygenic conditions – that is, complex conditions with no […]
April 20, 2021

Artificial intelligence could be used to triage patients suspected at risk of early stage oesophageal cancer

Artificial intelligence ‘deep learning’ techniques can be used to triage suspected cases of Barrett oesophagus, a precursor to oesophageal cancer, potentially leading to faster and earlier diagnoses, say researchers at the University of Cambridge. When researchers applied the technique to analysing samples obtained using the ‘pill on a string’ diagnostic […]