Related Science News – Page 196 – Innovita Research

Related Science News

November 6, 2019

Cell signalling breakthrough opens up new avenues for research

Researchers at the University of Liverpool have made a major breakthrough in the field of cell signaling. In humans, signaling in cells normally regulates cell growth and repair. However, abnormal cell signaling contributes to many diseases, including cancer and neurodegeneration. Therefore, identifying specific proteins that control cell signaling in health […]
November 5, 2019

Scientists identify protein that promotes brain metastasis

A protein that breast, lung and other cancers use to promote their spread – or metastasis – to the brain, has been identified by a team led by Weill Cornell Medicine and NewYork-Presbyterian investigators. The protein, CEMIP, will now be a focus of efforts to predict, prevent and treat brain […]
November 5, 2019

Nanoparticle orientation offers a way to enhance drug delivery

MIT engineers have shown that they can enhance the performance of drug-delivery nanoparticles by controlling a trait of chemical structures known as chirality — the “handedness” of the structure. Many biological molecules can come in either right-handed or left-handed forms, which are identical in composition but are mirror images of […]
November 5, 2019

New process of the antitumor response of NK cells in myeloma discovered

NK cells mean Natural Killer cells. They are part of the innate immune system. They are known primarily for their ability to recognize and kill tumor cells, cells infected by viruses and bacteria, or dying by apoptosis. Although evidence about their antitumoral capacity, how this activity occurred remained unknown. The […]
November 5, 2019

Blood Test Can Predict Prognosis in Deadly Brain Cancer

A blood test that measures the amount of cell-free DNA (cfDNA) in the bloodstream – called a liquid biopsy – correlates with how patients will progress after they are diagnosed with glioblastoma (GBM), the deadliest and most common primary brain tumor in adults. In a new study, researchers from the Abramson […]
November 5, 2019

Escaping Alzheimer’s

There is, in Colombia, a family with a tragic legacy of forgetfulness. “People in this large family get Alzheimer’s like clockwork at age 45-50,” said UC Santa Barbara neuroscientist Kenneth S. Kosik, the campus’s Harriman Professor of Neuroscience and co-director of the Neuroscience Research Institute. Their aggressive, genetic form of the […]
November 5, 2019

Researchers discover a way to turn Parkinson protein on itself

Researchers have found a way to create a super-inhibitor that effectively stops the development of Parkinsons by using the Parkinson disease itself as an active building block. Various neurodegenerative diseases such as Parkinson’s are closely linked to the aggregation of individual components called monomers of a specific protein that forms […]
November 5, 2019

Genes from ‘fossil’ virus in human DNA found to be active

Inserted in the human genome thousands of years ago, the genes can produce viral proteins without activating the whole virus. Genes from a virus that was stitched into the human genome thousands of years ago are active, producing proteins in the human brain and other tissues, according to researchers at […]
November 5, 2019

Marker reveals if benign-appearing meningiomas are perilous

A modified protein in benign-appearing meningiomas can reveal which are truly benign and which are more dangerous and require more aggressive treatment, researchers have discovered. The finding may also offer clues as to why these ‘benign’ tumors, which arise from the membranes that surround the brain and spinal cord, start […]
November 5, 2019

Yale Cancer Center study shows checkpoint inhibitor prolongs survival in patients with certain head and neck cancers

The checkpoint inhibitor pembrolizumab (Keytruda) increases the survival time of patients with advanced head and neck cancers, according to a new global study led by Yale Cancer Center (YCC). The data was published in the journal The Lancet. The findings of the phase 3 study show that, compared to the standard […]
November 5, 2019

High-tech foam offers new tool for developing stem cells

Two Florida State University researchers are developing a high-tech material currently used in athletic equipment and prosthetics into a special tool to better develop stem cells. The work could improve drug screening, disease modeling, precision medicine, and cell therapy. FAMU-FSU College of Engineering researchers Yan Li, an associate professor in […]
November 4, 2019

Lab leads effort to model proteins tied to cancer

Computational scientists, biophysicists and statisticians from Lawrence Livermore National Laboratory (LLNL) and Los Alamos National Laboratory (LANL) are leading a massive multi-institutional collaboration that has developed a machine learning-based simulation for next-generation supercomputers capable of modeling protein interactions and mutations that play a role in many forms of cancer. The […]
November 1, 2019

Advanced microscopy reveals unusual DNA structure

Sandia scientist pushes technology’s limits to see fundamental feature of stretched S-DNA. An advanced imaging technique reveals new structural details of S-DNA, ladder-like DNA that forms when the molecule experiences extreme tension. This work conducted at Sandia National Laboratories and Vrije University in the Netherlands provides the first experimental evidence […]
November 1, 2019

Dentists could diagnose dia­betes and pre­dia­betes

Do you know how many people in the world suffer from diabetes? About 422, according to World Health Organization, but we can’t know for certain. The issue here is that many people who are suffering from diabetes live without diagnosis. This is a huge problem, but scientists think that one […]
October 31, 2019

Skeleton Key

Researchers reveal structures of skeletal components in hair-like cilia. It’s not every day that scientists get to publish a paper on Halloween about a skeleton, but that’s what the laboratories of Alan Brown in the Blavatnik Institute at Harvard Medical School and Rui Zhang at Washington University in St. Louis just did. As reported […]
October 31, 2019

3D-Printed Device Finds ‘Needle in a Haystack’ Cancer Cells by Removing the Hay

Finding a handful of cancer cells hiding among billions of blood cells in a patient sample can be like finding a needle in a haystack. In a new approach enabled by 3D-printed cell traps, researchers are removing the hay to expose the cancer cells. Trapping the white blood cells – […]
October 31, 2019

Gabapentinoids Appear Increasingly to be Prescribed, Off-Label, for Cancer Pain

Between 2005 and 2015, as the opioid crisis in America came into focus, prescriptions for gabapentinoid medications — gabapentin and pregabalin — to adults with cancer saw a two-fold increase, a University of Michigan Rogel Cancer Center study has found. Gabapentin, which affects voltage-gated calcium channels in the brain, was originally approved […]
October 30, 2019

How our brains remember things depends upon how we learn them

The researchers from the Department of Experimental Psychology, the Wellcome Centre for Integrative Neuroimaging (WIN) and the Nuffield Department of Clinical Neurosciences, used an MRI scanner to observe changes in parts of the brain associated with learning and learned experiences while volunteers completed tasks that involved a reward. Participants also […]
October 30, 2019

Pediatric cancer study shows usefulness of gene expression analysis

Analyzing gene expression in tumor cells from children with cancer is more likely to reveal targets for therapy than analysis of DNA mutations, according to a new study led by researchers at the UC Santa Cruz Genomics Institute. The study, published in JAMA Network Open, looked at 144 tumor samples from 128 […]
October 30, 2019

Scientists identify critical window for treatment of Alzheimer’s Disease

Neuroscientists at the University of Southampton have made a significant development in understanding how Alzheimer’s disease spreads through the brain, discovering a significant period of time where medical intervention could halt its onset. A hallmark of Alzheimer’s disease is the accumulation of tau protein in neurons which causes loss of […]
October 30, 2019

Study links high-salt diet and cognitive impairment

A high-salt diet may negatively affect cognitive function by causing a deficiency of the compound nitric oxide, which is vital for maintaining vascular health in the brain, according to a new study in mice from Weill Cornell Medicine researchers. When nitric oxide levels are too low, chemical changes to the protein tau […]
October 30, 2019

Mapping cancer’s drug resistance could improve treatment

A set of powerful laboratory and computational techniques developed by scientists at Weill Cornell Medicine and two collaborating centers will enable investigators to map the capacity of tumors to develop resistance to drugs and drug combinations. The techniques – developed with researchers from the New York Genome Center (NYGC) and […]
October 30, 2019

Arthritis risk linked to obesity may be passed down through generations

Arthritis affects one in five Americans, but according to the Centers for Disease Control and Prevention, that number jumps to one in three among people with obesity. Now, new research from Washington University School of Medicine in St. Louis suggests obesity may increase arthritis risk not only in obese people […]
October 29, 2019

One avocado a day helps lower 'bad' cholesterol for heart healthy benefits

Move over, apples — new research from Penn State suggests that eating one avocado a day may help keep “bad cholesterol” at bay. According to the researchers, bad cholesterol can refer to both oxidized low-density lipoprotein (LDL) and small, dense LDL particles. In a randomized, controlled feeding study, the researchers […]
October 29, 2019

Signaling waves determine embryonic fates

Timing is everything for young cells waiting to determine their identities. Research by Rice University bioscientist Aryeh Warmflash and graduate student Sapna Chhabra shows homogenous colonies of human embryonic stem cells use dynamic molecular signaling waves that pass from cell to cell and trigger them to differentiate. Once prompted, the cells begin to organize […]
October 29, 2019

Crimped or straight? Lung fiber shape influences elasticity

Take a deep breath. Now exhale. Congratulations! You’ve just done something completely ordinary, yet so mysterious that scientists still don’t know everything about it. How oxygen and carbon dioxide enter and leave the bloodstream is well known, but scientists are just beginning to understand what happens to respiratory tissues as […]
October 28, 2019

New Nanotube Drug Delivery Shows Promise

A new drug delivery method designed by researchers at PNNL and Washington State University (WSU) has shown it can target and kill lung cancer cells. The research, led by Chun-Long Chen, a senior research scientist at PNNL and a joint faculty fellow at the University of Washington, and research partner […]
October 28, 2019

Researchers Explore Spinal Discs' Early Response to Injury and Ways to Improve It

Researchers may have found a way to press pause on spinal disc injuries, giving doctors more time to treat them before worse issues develop. The Penn Medicine-led team discovered that cells in the outer region of spinal discs become stressed and kick off a subpar healing process after injuries, which […]
October 28, 2019

Consuming alcohol leads to epigenetic changes in brain memory centers

Triggers in everyday life such as running into a former drinking buddy, walking by a once- familiar bar, and attending social gatherings can all cause recovering alcoholics to “fall off the wagon.” About 40 to 60 percent of people who have gone through treatment for substance abuse will experience some […]
October 28, 2019

Clues to improve cancer immunotherapy revealed

Cancer immunotherapy drugs trigger the body’s immune system to attack tumors and have revolutionized the treatment of certain cancers, such as lymphoma, lung cancer, and melanoma. Yet, while some patients respond well to the drugs, others don’t respond at all. Cancer immunologists want to change that. A new study by […]