Related Science News – Page 231 – Innovita Research

Related Science News

June 6, 2019

Molecular bait can help hydrogels heal wounds

Like fishermen, Rice University bioengineers are angling for their daily catch. But their bait, biomolecules in a hydrogel scaffold, lures microscopic stem cells instead of fish. These, they say, will seed the growth of new tissue to heal wounds. The team led by Brown School of Engineering bioengineer Antonios Mikos and graduate student Jason Guo […]
June 5, 2019

Zebrafish capture a 'window' on the cancer process

Cancer-related inflammation impacts significantly on cancer development and progression. New research has observed in zebrafish, for the first time, that inflammatory cells use weak spots or micro-perforations in the extracellular matrix barrier layer to access skin cancer cells. The research, led by the University of Bristol and published in Cell Reports, used translucent […]
June 5, 2019

Children’s brains reorganize after epilepsy surgery to retain visual perception

Children can keep full visual perception — the ability to process and understand visual information — after brain surgery for severe epilepsy, according to a study funded by the National Eye Institute (NEI), part of the National Institutes of Health. While brain surgery can halt seizures, it carries significant risks, […]
June 5, 2019

Exercise fine-tunes brain's connections, eases autism spectrum disorder in mouse model

A mouse model of autism has revealed how exercise changes the structure of the brain by eliminating the excess connections between neurons characteristic of autism spectrum disorder (ASD). After one month of voluntary running on a wheel, behavioral differences disappeared and structural differences in ASD model mice’s brains were reduced. […]
June 5, 2019

Choosing the right drug to fight cancer

Canadian researchers have discovered a molecular indicator of a mechanism that drives cancer progression, giving doctors the possibility of using precision medicine, that is, choosing which patients will respond to a particular anticancer drug. In a study published in Cancer Research, a team of biochemists at Université de Montreal found that a group […]
June 5, 2019

CRISPR baby mutation significantly increases mortality

A genetic mutation that a Chinese scientist attempted to create in twin babies born last year, ostensibly to help them fend off HIV infection, is also associated with a 21% increase in mortality in later life, according to an analysis by University of California, Berkeley, scientists. The researchers scanned more […]
June 5, 2019

New Clues for Delaying, Preventing Type 1 Diabetes

PNNL team pinpoints changes that ease immune attack. PNNL scientist Wei-Jun Qian and colleagues have contributed to a study that offers clues for delaying or even preventing the autoimmune attack that’s at the core of type-1 diabetes. The study team, led by Rohit Kulkarni at the Joslin Diabetes Center at […]
June 5, 2019

Physics could answer questions about breast cancer spreading to bones

Researchers hope to learn how cancer cells generate enough force to move from a tumor site through the body and then settle into bones. To fully understand why breast cancer spreads, or metastasizes, you must also consider the how. That's what researchers in a biophysics and imaging laboratory in the […]
June 4, 2019

Newly Discovered Immune Cell Linked to Type 1 Diabetes

In a discovery that might be likened to finding medicine’s version of the Loch Ness monster, a research team from Johns Hopkins Medicine, IBM Research and four collaborating institutions is the first to document the existence of long-doubted “X cell,” a “rogue hybrid” immune system cell that may play a […]
June 4, 2019

Childhood Adversity Linked to Earlier Puberty, Premature Brain Development, and Greater Mental Illness

Growing up in poverty and experiencing traumatic events like a bad accident or sexual assault can impact brain development and behavior in children and young adults. Low socioeconomic status (L-SES) and the experience of traumatic stressful events (TSEs) were linked to accelerated puberty and brain maturation, abnormal brain development, and […]
June 4, 2019

New genetic weapons challenge sickle cell disease

Help for patients with sickle cell disease may soon come from gene editing to fix the mutation that causes the disease and boost the patient’s own protective fetal hemoglobin. New research shows that using CRISPR-Cas9 and a corrective short DNA template to repair the sickle cell mutation in a patient’s hematopoietic stem cells (HSCs) could be efficient […]
June 4, 2019

Yale study shows drug increases survival for bladder cancer patients

There are no approved treatment options for patients with advanced bladder cancer after they’ve received standard chemotherapy and immune treatments, but the results of a phase II clinical trial led by Yale Cancer Center and Smilow Cancer Hospital researchers demonstrate an effective treatment for this deadly disease. The findings were presented […]
June 4, 2019

New tool to make detecting changes in DNA much easier

Diagnosing genetic diseases is a difficult task. Biomarkers are not always identified and analysing DNA takes a considerable amount of time. But now thanks to advancements in DNA testing diseases caused by genetic changes could be detected more readily. Scientists from the University of Edinburgh say that this achievement allows […]
June 3, 2019

After 2 Years, Immunotherapy Shows Doubled Median Survival Time for Advanced Lung Cancer Patients

A large, randomized immunotherapy clinical trial continues to show improved overall survival and progression-free survival in advanced lung cancer patients, researchers reported at this year’s American Society for Clinical Oncology meeting. The update on the KEYNOTE-189 trial provides nearly two years data on use of the immunotherapy drug pembrolizumab in combination with platinum-based chemotherapy […]
June 3, 2019

New Way to Predict Complications After Larynx Cancer Surgery

A technique that illuminates blood flow during surgery predicted which head and neck cancer patients were likely to have issues with wound healing. It could enable surgeons to make adjustments during surgery or recovery to improve outcomes. A team of surgeons at the University of Michigan Rogel Cancer Center found the approach […]
June 3, 2019

Breast Milk and Obesity

New research suggests the composition of breast milk in normal weight mothers differs from that of overweight mothers, and that variations in small molecule metabolites found in breast milk are possible risk factors for childhood obesity. It’s known that maternal obesity is one of the strongest predictors of childhood obesity. […]
May 31, 2019

Study details regulation of a multi-drug transporter

Vanderbilt University researchers have discovered how a protein pump distinguishes between chemicals that it will expel from a cell and inhibitors that block its action. The pump, called P-glycoprotein, protects cells by removing potentially harmful chemicals, but it contributes to drug resistance when those chemicals are therapeutic drugs — which […]
May 31, 2019

New regulator of immune responses discovered

Scientists have identified a new internal regulator that helps control the body’s response to fight infection. The discovery could be a target for new drugs to tackle autoimmune diseases, such as lupus and scleroderma, where healthy tissues are attacked by the body’s own immune system. The international collaboration was led […]
May 31, 2019

Gut Bacteria Influence Autism-like Behaviors in Mice

Autism spectrum disorder (ASD) affects an estimated one in 59 people in the United States, causing a variety of difficulties with social communication and repetitive behavior. Many factors, including genetic and environmental effects, are believed to influence symptoms, and there are no approved treatments. Now, using mouse models, Caltech researchers […]
May 31, 2019

Research Provides Insight into Genetic Link to Potential Treatment Response Among BRCA1/2 Breast Cancer Patients

New findings from researchers in the Perelman School of Medicine at the University of Pennsylvania provide clues about immune response of tumors in patients with BRCA 1/2-related breast cancers. The research, published in the journal Clinical Cancer Research, could shape treatment strategies and clinical trial design for these patients, who make up about […]
May 31, 2019

Princeton researchers discover link between circadian clock and fat metabolism

The enzyme Nocturnin, which governs daily tasks such as fat metabolism and energy usage, works in an entirely different way than previously thought, reported a team of researchers at Princeton University. The newly discovered mechanism reveals the molecular link between the enzyme’s daily fluctuations and its energy-regulating role in the […]
May 31, 2019

UCI research helps shed new light on circadian clocks

Can your liver sense when you’re staring at a television screen or cellphone late at night? Apparently so, and when such activity is detected, the organ can throw your circadian rhythms out of whack, leaving you more susceptible to health problems. That’s one of the takeaways from two new studies […]
May 31, 2019

Life isn’t over: how best to communicate with people living with dementia

When Sandie Read was diagnosed with dementia at 57, she felt a mixture of fear, anxiety and depression. Fifteen years later and not only is she offering support to fellow sufferers but she’s also working with researchers to improve the way people communicate and interact with those living with the […]
May 31, 2019

Vaginal microbiome may influence preterm birth risk

The composition of the vaginal microbiome is an indicator of whether a woman will experience preterm birth, or carry the fetus full term, according to one of the largest studies of its kind.  The findings are publishedmicrobio in Nature Medicine. The microbiome is the collection of organisms growing in a particular location. […]
May 30, 2019

Researchers spot tell-tale signs of potentially fatal cardiac arrest

Hypertrophic cardiomyopathy is the leading cause of sudden cardiac death in young people (such as the unexpected near fatal cardiac arrest suffered by the-then 23 year old footballer Fabrice Muamba), but the microscopic heart muscle abnormalities behind these tragic events can only be picked up in a post-mortem. Now, in […]