Related Science News – Page 18 – Innovita Research

Related Science News

March 3, 2020

Study underscores importance of molecular highways for organ health

Turns out, even your cells hate traffic jams. In order for cells to function properly, they need to be able to coordinate traffic within their walls and let information flow in and out. Inside a cell, molecules, organelles and information travel along microtubules, which work like highways or conveyor belts. […]
March 2, 2020

Research reveals link between high cholesterol levels and risk of aortic valve disease

Researchers from The George Institute for Global Health at the University of Oxford have found that while having high cholesterol levels does not influence your risk of aortic or mitral valve regurgitation, it does increase your risk of developing another major heart valve disease – aortic stenosis. Aortic stenosis is […]
March 2, 2020

New chemo combo shows promise versus pancreatic cancer

The targeted drug palbociclib may boost the effectiveness of chemotherapy in pancreatic cancer if the two treatments are given in the right sequence, according to new preclinical research by Weill Cornell Medicine and NewYork-Presbyterian investigators. The study, published in Cancer Cell, found that palbociclib may stop pancreatic cancer cells from repairing […]
March 2, 2020

Stable conditions during cell division

Errors during cell division can trigger the development of cancer. No wonder that this central process is controlled by multiple regulators and guards. Alex Bird's research group at the Max Planck Institute of Molecular Physiology has discovered a hitherto unknown key player and how it provides the necessary stability to […]
March 2, 2020

New Cas9 variant makes genome editing even more precise

CRISPR-Cas9 has revolutionized the field of genetics by its ability to cut DNA at defined target sites. Researchers are using the Cas9 enzyme to specifically switch off genes, or insert new DNA fragments into the genome. But no matter how specific the Cas9 enzyme is – sometimes it cuts where […]
March 2, 2020

A weak heart also damages the brain

If the heart pumps too little blood into the body, the brain is usually not adequately supplied with oxygen. Until now, however, it was unclear how this affects brain structure. Researchers at the Max Planck Institute for Human Cognitive and Brain Sciences together with colleagues from the Leipzig Heart Clinic, […]
March 2, 2020

An Epigenetic Clock for Skeletal Muscle

Epigenetic clocks are multiplying year by year. Each is a weighted algorithmic combination of the status of various methylation sites on the genome, built by analyzing the epigenome of many different people at different ages in order to arrive at correlations with chronological age, or, more usefully, with metrics such as mortality risk that reflect biological […]
March 2, 2020

Length of pregnancy alters the child's DNA

Researchers from Karolinska Institutet led by Professor Erik Melén have together with an international team mapped the relationship between the length of pregnancy and chemical DNA changes in more than 6,000 newborn babies. For each week's longer pregnancy, DNA methylation changes in thousands of genes were detected in the umbilical […]
March 2, 2020

New probe developed to detect a common target for anti-inflammatory drugs

Scientists have developed a probe named CoxFluor that can distinguish between Cyclooxygenase-2, an enzyme that plays a major role in driving the progression of cancer, and the enzyme Cyclooxygenase-1, which is expressed in all cells. Led by Jefferson Chan, a chemist at the University of Illinois at Urbana-Champaign, a paper detailing […]
March 2, 2020

Fasting at night or in the morning? Listen to your biological clock, says new research

In recent years, diet trends such as Intermittent Fasting have popularized the practice of delayed or restricted eating for many individuals looking to manage caloric intake. Still, many people open to restructuring their schedules have the same question: When is the right time to avoid eating? According to a new […]
March 2, 2020

Intensive Blood Pressure Control Can Extend Life up to Three Years

A new study by investigators at Brigham and Women’s Hospital puts the results of a landmark trial about blood pressure control into terms that may be easier to interpret and communicate to patients. When data from The Systolic Blood Pressure Intervention Trial (SPRINT) were published in 2015, the medical community responded enthusiastically […]
March 2, 2020

Widowhood Accelerates Cognitive Decline Among Those at Risk for Alzheimer's Disease

The death of a spouse often means the loss of intimacy, companionship and everyday support for older adults. A new study finds that widowhood can have another profound effect: It may accelerate cognitive decline. Investigators from Brigham and Women’s Hospital and Massachusetts General Hospital analyzed older, cognitively normal Americans enrolled […]
March 2, 2020

Study suggests way to improve cytomegalovirus testing

Many tests for cytomegalovirus infection are difficult to interpret because most of its DNA fragments are too small to be detected in the blood of infected people through current assays.  Laboratory medicine experts at the University of Washington School of Medicine are looking at this problem to find better ways […]
February 29, 2020

Resetting the Biological Clock with Flip of the Molecular Switch

Scientists from UC San Diego, UC Santa Cruz and Duke University synchronized their research watches to study what makes our biological clocks tick. Specifically they set out to understand why some people are what they call extreme “morning larks” who operate on a shorter 20-hour cycle compared to a regular 24-hour pattern. […]
February 28, 2020

Parental use of digital media gives slower language development in children

A research project at Linköping University has shown that children whose parents often use digital media develop language more slowly than others. For three years, Associate Professor Anett Sundqvist and her research group in the Child and Infant Lab at Linköping University have studied young children and their development in […]
February 28, 2020

A molecular atlas of skin cells

Our skin protects us from physical injury, radiation, and microbes, and at the same time produces hair and facilitates perspiration. Details of how skin cells manage such disparate tasks have so far remained elusive. Now, researchers at Karolinska Institutet in Sweden have systematically mapped skin cells and their genetic programs, […]
February 28, 2020

Breast cancer study may help predict treatment response

Researchers at Vanderbilt University Medical Center are reporting another advance in the understanding and treatment of triple-negative breast cancer, which is particularly aggressive and difficult to treat. Their findings, detailed in the journal Clinical Cancer Research, offer new hope for identifying patients most likely to respond to the latest treatments. “This […]
February 28, 2020

Eating fruit during pregnancy boosts babies’ brain development, new study confirms

A followup to a University of Alberta study done in 2016 confirms that pregnant women who eat more fruit during pregnancy may be giving their babies’ cognitive development a boost. “Our research followed up on results from the original CHILD Cohort Study, which found that fruit consumption in pregnant mothers influences […]
February 28, 2020

Cells carrying Parkinson’s mutation could lead to new model for studying disease

Parkinson’s disease researchers have used gene-editing tools to introduce the disorder’s most common genetic mutation into marmoset monkey stem cells and to successfully tamp down cellular chemistry that often goes awry in Parkinson’s patients. The edited cells are a step toward studying the degenerative neurological disorder in a primate model, […]
February 28, 2020

Sugar-poor diets wreak havoc on bumblebee queens’ health

Without enough sugar in their diets, bumblebee queens can experience difficulty reproducing and shorter lifespans. Hollis Woodard, assistant professor of entomology at UCR, has conducted multiple studies showing how loss of plant availability negatively affects the prolific pollinators. Previous research indicates a queen’s diet can impact how quickly her brood develops, or […]
February 28, 2020

Researchers receive Canada-UK funding to develop AI-powered microrobots to capture brain cells

Researchers at the University of Toronto’s Donnelly Centre for Cellular and Biomolecular Research have received a funding boost to help realize their vision of using tiny robots controlled by artificial intelligence to one day find and capture rare stem cells from brain tissue for therapy. Working with Mike Shaw, a machine learning expert […]
February 27, 2020

New possible treatment strategy against fatty liver disease

Researchers at Karolinska Institutet in Sweden have identified a molecular pathway that when silenced could restore the normal function of immune cells in people with fatty liver disease. The findings could lead to new strategies for treating the condition, which is a major health risk for people with obesity. The […]
February 27, 2020

Cognitive impairment after intensive care linked to long-lasting inflammation

People who have been treated in intensive care commonly suffer from residual cognitive impairment, but the reason for this is unknown. Researchers at Karolinska Institutet now link cognitive impairment with lasting inflammation and a potential treatment target. The results are presented in the scientific journal Intensive Care Medicine. Every year, […]
February 27, 2020

Global group to investigate links between rare genomic disorders and psychiatric conditions

Rare genetic disorders caused by small changes in a person’s genetic make-up affect fewer than 1 in 2,000 people globally – but they are a major cause of developmental and psychiatric conditions, such as autism spectrum disorder, schizophrenia, attention deficit hyperactivity disorder, and intellectual disability. Recent advances in technologies to […]
February 27, 2020

In Utero Stem Cell Transplants, Enzyme Replacement May Offer New Treatments for Deadly Metabolic Disorders

Administering stem cell or enzyme therapy in utero may be a path to alleviating some congenital diseases that often result in losing a pregnancy, according to a new study in mice by UC San Francisco researchers, who showed that stem cells can enter the fetal brain during prenatal development and make up for cells that fail to make an essential protein. Each year, about 24,000 women […]
February 26, 2020

How Resident Microbes Restructure Body Chemistry

The makeup of our microbiomes — the unique communities of bacteria, viruses and other microbes that live in and on us — have been linked, with varying degrees of evidence, to everything from inflammatory bowel disease to athletic performance. But exactly how could such tiny organisms have such immense influences […]
February 26, 2020

New Clue Behind Age-Related Diseases and Food Spoilage Discovered

Exotic molecule linked to ozone also at work in chronic diseases and cancers, and even the decomposition of food. Scientists at the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have made a surprising discovery that could help explain our risk for developing chronic diseases or cancers as […]
February 26, 2020

DNA Misfolding in White Blood Cells Increases Risk for Type 1 Diabetes

It’s known that genetics, or an inherited genome, is a major determinant of one’s risk for autoimmune diseases, like Type 1 diabetes. In human cells, a person’s genome—about six feet of DNA—is compressed into the micrometer space of the nucleus via a three-dimensional folding process. Specialized proteins decode the genetic […]
February 25, 2020

Establishment of a cat genome analysis platform

Cats share around 250 types of genetic diseases with humans, and they are seen as a next-generation animal model for diseases. During his days as a veterinarian, Project Professor Watanabe saw many animals succumb to diseases, including genetic diseases which were incurable. He presses forward with his research on cat […]
February 25, 2020

Diabetes in mice cured rapidly using human stem cell strategy

Researchers have converted human stem cells into insulin-producing cells and demonstrated in mice infused with such cells that blood sugar levels can be controlled and diabetes functionally cured for nine months. The findings, from researchers at Washington University School of Medicine in St. Louis, are published online in the journal […]