Related Science News – Page 91 – Innovita Research

Related Science News

July 21, 2020

How good gut bacteria help reduce the risk for heart disease

Scientists have discovered that one of the good bacteria found in the human gut has a benefit that has remained unrecognized until now: the potential to reduce the risk of heart disease. The bacteria’s activity in the intestines reduces the production of a chemical that has been linked to the […]
July 21, 2020

Modeling neuronal cultures on 'brain-on-a-chip' devices

For the past several years, Lawrence Livermore National Laboratory (LLNL) scientists and engineers have made significant progress in development of a three-dimensional “brain-on-a-chip” device capable of recording neural activity of human brain cell cultures grown outside the body. Now, LLNL researchers have a way to computationally model the activity and structures of neuronal communities […]
July 20, 2020

Human Sperm Stem Cells Grown in Lab, an Early Step Toward Infertility Treatment

Infertility affects one in seven men of reproductive age worldwide. One idea for treating male sterility is spermatogonial stem cell (SSC) therapy. In this approach, sperm stem cells in the testis are transferred to a test tube, cultured and nudged into becoming fully fledged sperm. However, a key bottleneck has […]
July 20, 2020

Researchers Discover Two Paths of Aging and New Insights on Promoting Healthspan

Molecular biologists and bioengineers at the University of California San Diego have unraveled key mechanisms behind the mysteries of aging. They isolated two distinct paths that cells travel during aging and engineered a new way to genetically program these processes to extend lifespan. The research was described in the journal […]
July 20, 2020

Custom nanoparticle regresses tumors when exposed to light

A unique nanoparticle to deliver a localized cancer treatment inhibits tumor growth in mice, according to a team of Penn State researchers. The nanoparticles, developed by Daniel Hayes, associate professor of biomedical engineering, have a specific chemistry that allows a microRNA (miRNA) to attach to it. A miRNA is a […]
July 20, 2020

Molecular "Tails" Are Secret Ingredient for Gene Activation in Humans, Yeast, and Other Organisms

It might seem as though humans have little in common with the lowly yeast cell. Humans have hair, skin, muscles, and bones, among other attributes. Yeast has, well, none of those things. But besides their obvious differences, yeast, and humans, and much of life for that matter, have a great […]
July 20, 2020

Imaging Enzyme Activity with Ultrasound

Ultrasound imaging, as most people are familiar with it, is used for taking pictures of a fetus while it is still inside the womb, but it has other medical purposes, such as diagnosing diseases of organs and tissues. For years, Caltech's Mikhail Shapiro has been working to extend ultrasound imaging into […]
July 20, 2020

Self-Eating Decisions

New study sheds light on how nutrient-starved cells recycle internal components. The idea of the cell as a city is a common introduction to biology, conjuring depictions of the cell’s organelles as power plants, factories, roads, libraries, warehouses and more. Like a city, these structures require a great deal of […]
July 20, 2020

Turning off “junk DNA” may free stem cells to become neurons

For every cell in the body there comes a time when it must decide what it wants to do for the rest of its life. In an article published in the journal PNAS, National Institutes of Health researchers report for the first time that ancient viral genes that were once […]
July 17, 2020

Novel Hyperbaric Oxygen Therapy Protocol Can Improve Cognitive Function of Healthy Older Adults

The Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center, together with the Sackler School of Medicine and Sagol School of Neuroscience at Tel Aviv University, announced today that a peer-reviewed study has demonstrated for the first time that hyperbaric oxygen therapy (HBOT) can significantly enhance the cognitive performance of healthy older adults. […]
July 17, 2020

Penn Researchers Find Three Distinct Immune Responses for Sicker COVID-19 Patients

Researchers from the Penn Institute of Immunology discovered three distinct immune responses to the SARS-CoV2 infection that could help predict the trajectory of disease in severe COVID-19 patients and may ultimately inform how to best treat them. The findings were published in Science. “For patients who are hospitalized with COVID-19, there isn’t just […]
July 17, 2020

Researchers 3D print a working heart pump with real human cells

In a groundbreaking new study, researchers at the University of Minnesota have 3D printed a functioning centimeter-scale human heart pump in the lab. The discovery could have major implications for studying heart disease, the leading cause of death in the United States killing more than 600,000 people a year. The […]
July 17, 2020

Simple twist of DNA determines fate of placenta

The development of the mammalian placenta depends upon an unusual twist that separates DNA’s classic double helix into a single-stranded form, Yale researchers report in the journal Nature. The Yale team also identified the molecular regulator that acts upon this single strand to accelerate or stop placental development, a discovery with […]
July 17, 2020

Researchers discover potential treatment for rare degenerative disease

Yale pharmacology professor Barbara Ehrlich and her team have uncovered a mechanism driving a rare, lethal disease called Wolfram Syndrome and also a potential treatment. Their findings appear in the Proceedings of the National Academy of Sciences. Wolfram Syndrome — a progressive degenerative disease that affects about one in 500,000 people worldwide […]
July 17, 2020

Megaphages harbor mini-Cas proteins ideal for gene editing

The DNA-cutting proteins central to CRISPR-Cas9 and related gene-editing tools originally came from bacteria, but a newfound variety of Cas proteins apparently evolved in viruses that infect bacteria. The new Cas proteins were found in the largest known bacteria-infecting viruses, called bacteriophages, and are the most compact working Cas variants […]
July 16, 2020

MicroRNA-34a Promotes Vascular Cellular Senescence and Consequent Calcification

With the growing interest in the accumulation of senescent cells as an important cause of aging, and more funding flowing into this part of the field, researchers are uncovering numerous direct links between cellular senescence and age-related conditions. Senescent cells cause harm to tissues via their inflammatory secretions, the senescence-associated […]
July 16, 2020

Air pollution affects brain development – but when does the damage start?

The emergency rooms in Barcelona were collapsing under the pressure. Hundreds of patients were arriving in desperate need as they struggled to breathe, while intensive care units struggled to cope with the sudden influx of respiratory problems. Epidemiologists scrambled to trace the source of the outbreak. This epidemic in the […]
July 16, 2020

Fruit flies help shed light on tumor formation, migration and growth

What can the common fruit fly teach us about cancer? “Over the last few decades, the fruit fly – Drosophila melanogaster – has become a successful model for studying human cancers,” said Wu-Min Deng, Ph.D., professor of biochemistry and molecular biology and the Gerald and Flora Jo Mansfield Piltz Professor of […]
July 16, 2020

Flatworms muscle new eyes' wiring into their brains

Peter Reddien's lab at the Whitehead Institute takes a step forward in understanding how neural circuits could be regenerated in adults. If anything happens to the eyes of the tiny, freshwater-dwelling planarian Schmidtea mediterranea, they can grow them back within just a few days. How they do this is a scientific conundrum […]
July 15, 2020

Stem Cell Exhaustion in the Aging Lung

Stem cell activity declines with age throughout the body. In some cases this is because stem cells become less active in response to changes in the signaling environment. In other cases, the cells are damaged or the populations greatly reduced. The consequence of this decline is that fewer daughter somatic […]
July 15, 2020

Scientists discover way to stop spread of devastating childhood cancer

Researchers at the University of East Anglia and the University of Manchester have made an important breakthrough that could lead to ‘kinder’ treatments for children with bone cancer, and save lives. Current treatment is grueling, with outdated chemotherapy cocktails and limb amputation. But despite all of this, the five-year survival […]
July 15, 2020

Multiple Purkinje cell types: A new logic of cerebellar organization in zebrafish

In a study published in PNAS, researchers from Karolinska Institutet, the Royal Institute of Technology (KTH), Nagoya University and Technische Universität Braunschweig show an undiscovered heterogeneity of adult zebrafish Purkinje cells, revealing the existence of anatomically and functionally distinct cell types. The cerebellum, sometimes referred to as the “tree of […]
July 15, 2020

Deconstructing glioblastoma complexity reveals its pattern of development

Brain cancers have long been thought of as being resistant to treatments because of the presence of multiple types of cancer cells within each tumor. A new study uncovers a cancer cell hierarchy that originates from a single cancer cell type, which can be targeted to slow cancer growth. The […]
July 15, 2020

Sodium found to regulate the biological clock of mice

A new study from McGill University shows that increases in the concentrations of blood sodium can have an influence on the biological clock of mice, opening new research avenues for potentially treating the negative effects associated with long-distance travel or shift work. The findings, published in Nature by former McGill Ph.D. student […]
July 15, 2020

New $3.7M grant to support research exploring mysterious link between cancer, HIV/AIDS

Research has found that those living with HIV have a higher risk for certain kinds of cancers—such as lung cancer. Now, with a new five-year, $3.7 million grant from the National Cancer Institute (NCI), researchers from Case Western Reserve University hope to find out why. Ge Jin, professor at the […]
July 15, 2020

Study Suggests Method to Starve Pancreatic Cancer Cells

A University of Michigan-led study is shedding new light on the way pancreatic cancer cells turn nearby connective tissue cells into co-conspirators in their deadly growth. The findings, which appear in Nature Metabolism, also suggest a new potential strategy against pancreatic cancer by identifying critical components of metabolic cross-talk between cells that might be […]
July 15, 2020

New Drug Combo Shows Promise in Fight Against High Cholesterol

If you’ve ever been diagnosed with high cholesterol, also known as hyperlipidemia, your doctor has probably prescribed a statin. And while statins have been the go-to drug for managing cholesterol for nearly 25 years, there’s a new weapon in the fight. Recent studies suggest that adding a new class of medications — either […]
July 15, 2020

Swap Meet

Researchers at Harvard Medical School, the Broad Institute of MIT and Harvard and Brigham and Women’s Hospital have uncovered a genetic mechanism that helps drive clonal hematopoiesis, a common age-related condition known to increase the risk of blood cancer and cardiovascular disease. In clonal hematopoiesis or CH, some blood stem […]
July 15, 2020

NFL outperforms other blood tests to predict and diagnose traumatic brain injury

A study from the National Institutes of Health showed that neurofilament light chain (NfL) delivered a superior diagnostic and prognostic performance as a blood biomarker for mild, moderate, and severe traumatic brain injury (TBI) when compared to blood proteins glial fibrillary acidic protein, tau, and ubiquitin c-terminal hydrolase-L1. The research […]
July 14, 2020

It is Challenging to Find Support for Evolutionary Trade-offs Between Reproduction and Aging in Human Data

The disposibility theory of aging is one of numerous evolutionary theories of aging that seek to explain why aging exists and is near universal across species. In this case, aging is viewed as the inevitable result of trade-offs between resources allocated to reproduction versus resources allocated to tissue maintenance. Like […]