Related Science News – Page 107 – Innovita Research

Related Science News

June 29, 2020

Genes affecting brains and brawn?

Genetic deletions associated with neurodevelopmental disorders also important for development elsewhere in the body. Genes located in “copy number variants” (CNVs) — parts of chromosomes that are missing in some individuals and duplicated in others — that are associated with neurodevelopmental disorders affect more than just brain development, according to […]
June 29, 2020

Just stare at the red light – scientists found a new way to reduce age-related eyesight decline

Aging is no fun. Your entire body is getting worn out and it might pose certain health risks. One of the worst parts of aging is declining vision. Once you hit 40, your colour sensing ability and general sharpness of your eyes starts declining rapidly. But scientists from UCL say […]
June 29, 2020

How cancer drugs find their targets

In the watery inside of a cell, complex processes take place in tiny functional compartments called organelles. Energy-producing mitochondria are organelles, as is the frilly golgi apparatus, which helps to transport cellular materials. Both of these compartments are bound by thin membranes. But in the past few years, research at […]
June 29, 2020

A focused approach to imaging neural activity in the brain

When neurons fire an electrical impulse, they also experience a surge of calcium ions. By measuring those surges, researchers can indirectly monitor neuron activity, helping them to study the role of individual neurons in many different brain functions. One drawback to this technique is the crosstalk generated by the axons […]
June 29, 2020

Study to recruit thousands of participants to reveal exercise impact at the molecular level

In the largest exercise research program of its kind, researchers are poised to collect and turn data from nearly 2,600 volunteers into comprehensive maps of the molecular changes in the body due to exercise. It is well known that physical activity has substantial health benefits, but we do not fully […]
June 29, 2020

Researchers Identify Novel Genetic Variants Linked to Type-2 Diabetes

After examining the genes of more than 200,000 people all over the world who have type-2 diabetes, researchers from the Perelman School of Medicine at the University of Pennsylvania and the Veterans Health Administration’s (VHA) Corporal Michael J. Crescenz Veterans Affairs Medical Center (CMCVAMC) found hundreds of genetic variants never before linked to the disease. The study also […]
June 29, 2020

Dementia May Develop 7 Years Earlier for Adults with Inflammatory Bowel Disease

Older adults with chronic inflammation of the gastrointestinal tract may develop dementia more than seven years earlier than those without the condition, according to a new study by researchers at UC San Francisco and Taipei Veterans General Hospital in Taiwan. A review of nearly 19,200 Taiwanese patients found that those […]
June 29, 2020

Machine learning predicts side effects from chemotherapy

In collaboration with Rigshospitalet, researchers from DTU Health Technology have developed a machine learning model that can predict chemotherapy-associated nephrotoxicity, a particularly significant side effect in patients treated with cisplatin. Testicular cancer is the most common cancer in young men. The number of new cases is increasing worldwide. There is […]
June 29, 2020

The human brain tracks speech more closely in time than other sounds

The way that speech processing differs from the processing of other sounds has long been a major open question in human neuroscience. Researchers at Aalto University have endeavored to answer this by investigating brain representations for naturally spoken words using machine learning models and comparing them with representations of environmental […]
June 29, 2020

Genetics research produces clinical trial for ‘Childhood Alzheimer’s’

An arthritis drug is to be trialed as a treatment for children with a fatal metabolic disorder which causes neurological deterioration thanks to the University of Manchester researchers. Sanfilippo syndrome is a rare genetic disease with devastating effects on the central nervous system which affects around 1 in 70,000 children, […]
June 29, 2020

Study gives insights into how human fat cells are affected by age

Knowledge of how human fat tissue is affected by age has long been defined by numerous mouse-based studies. Researchers at Karolinska Institutet in Sweden have now, for the first time, been able to conduct a prospective study on humans that provides novel insights into how our fat cells reduce lipid […]
June 29, 2020

"Where are My Keys?" and Other Memory-Based Choices Probed in the Brain

Most of us know that feeling of trying to retrieve a memory that does not come right away. You might be watching a romantic comedy featuring that famous character actor who always plays the best friend and finds yourself unable to recall her name (it's Judy Greer). While memory retrieval […]
June 28, 2020

A Study of Environmental Factors Correlating with the Odds of Becoming a Centenarian

The evidence to date strongly suggests that environmental factors determine longevity for the vast majority of people. If there are significant longevity-affecting gene variants out there, then they have small and unreliable effects (APOE), or are restricted to tiny lineages (SERPINE1), or both. The overwhelming majority of contributions to longevity […]
June 28, 2020

T Cells Must Work Harder to Survive in an Old Body

T cells of the adaptive immune system collectively become less functional with age. The immune system as a whole becomes more inflammatory and less effectively, a state described by the terms inflammaging and immunosenescence. Researchers here note that T cells struggle to survive in the aged environment, and are as […]
June 28, 2020

Senescence-Associated Secretory Phenotype Proteins as a Biomarker of Aging

In today's open access research, the authors report on the generation of a biomarker of aging from the study of proteins secreted by senescent cells. Low cost assays that map closely to biological age, the burden of damage, are a potentially useful tool for research and development of rejuvenation therapies. […]
June 28, 2020

Demonstrating a Senolytic Chimeric Antigen Receptor T Cell Therapy

Chimeric antigen receptor (CAR) T cell therapies target specific surface features on other cells by providing T cells with a way to recognize that feature – the CAR. T cells so equipped will selectively destroy other cells with the target surface feature. To produce a CAR T cell therapy, a […]
June 26, 2020

AI dual-stain approach improved accuracy, efficiency of cervical cancer screening in NIH study

In a new study, a computer algorithm improved the accuracy and efficiency of cervical cancer screening compared with cytology (Pap test), the current standard for follow-up of women who test positive with primary human papillomavirus (HPV) screening. The new approach uses artificial intelligence (AI) to automate dual-stain evaluation and has […]
June 26, 2020

U of A researchers identify more than 100 toxic chemicals in cannabis smoke

University of Alberta engineering researchers have characterized the potentially hazardous particles in cannabis smoke and have raised awareness about their potential health effects. “It's not out of line to say there's a potential health risk in marijuana smoke, and there's not nearly enough research,” said Robert Nishida, a U of […]
June 26, 2020

New tool for assessing heart muscle cells helps unlock their potential

Heart muscle cells made from stem cells could be used to screen drugs or develop cell-based therapies for heart disease. But these cells, called cardiomyocytes, are often immature, disorganized, and unable to behave together like working muscle tissue. University of Wisconsin–Madison researchers have created a new way to study how […]
June 26, 2020

Mapping the Molecular Health Benefits of Exercise

PNNL proteomics researchers are part of a large consortium tracing the benefits of exercise on an unprecedented scale Exercise helps our bodies and minds. It is a common prescription to build strength and help slow heart disease, diabetes, anxiety, and depression. But how does exercise change the molecular makeup of […]
June 25, 2020

Drug Discovery Seeds/Molecular Targets for the Rare Diseases Involving Bones and Growth Plate Cartilage

NineSigma, representing a Japanese pharmaceutical company with an expertise in bone-related diseases as one of their future focal areas, seeks a potential collaboration partner(s) that possess drug discovery seeds or molecular targets for rare diseases involving bones and growth plate cartilage. Through collaboration with a potential partner(s), the client ultimately aims to […]
June 25, 2020

Discovery of aggressive cancer cell types by Vanderbilt researchers made possible with machine learning techniques

By applying unsupervised and automated machine learning techniques to the analysis of millions of cancer cells, Rebecca Ihrie and Jonathan Irish, both associate professors of cell and developmental biology, have identified new cancer cell types in brain tumors. Machine learning is a series of computer algorithms that can identify patterns within enormous quantities […]
June 25, 2020

NIH investigators hope CD47 study leads to broad-spectrum infectious diseases immunotherapy

National Institutes of Health investigators and colleagues have discovered that when the immune system first responds to infectious agents such as viruses or bacteria, a natural brake on the response prevents overactivation. Their new study in mBio describes this brake and the way pathogens such as SARS-CoV-2, the virus that causes […]
June 25, 2020

Researchers use electric fields to herd cells like flocks of sheep

Princeton researchers have created a device that can herd groups of cells like sheep, precisely directing the cells’ movements by manipulating electric fields to mimic those found in the body during healing. The technique opens new possibilities for tissue engineering, including approaches to promote wound healing, repair blood vessels, or […]
June 23, 2020

Pioneering research reveals certain human genes relate to gut bacteria

The role genetics and gut bacteria play in human health has long been a fruitful source of scientific enquiry, but new research marks a significant step forward in unraveling this complex relationship. Its findings could transform our understanding and treatment of all manner of common diseases, including obesity, irritable bowel […]
June 23, 2020

The regulation of glycemia after stroke improves neurological recovery in diabetes

In a study in mice, researchers at Karolinska Institutet have discovered a new potential therapeutic approach to facilitate neurological recovery in people with diabetes suffering from a stroke. The treatment strategy is based on the chronic normalization of hyperglycemia after stroke. The scientists hope that these new results, presented in […]
June 23, 2020

Skin cancer: men are genetically more prone

As COVID-19 restrictions loosen this summer, Canadians will spend more time outdoors and make the most of the sunshine. A new study from McGill University suggests why men may be more genetically prone to develop skin cancer. The research led by Professor Ian Watson of McGill’s Goodman Cancer Research Centre […]
June 23, 2020

In a new report, paleontologists Lauren Sallan and Jack Stack re-examine the “enigmatic and strange” prehistoric fish Tanyrhinichthys mcallisteri. (Image: Nobu Tamura

An international research team led by Dr. Tali Ilovitsh of the Biomedical Engineering Department at TAU developed a noninvasive technology platform for gene delivery into breast cancer cells. The technique combines ultrasound with tumor-targeted microbubbles. Once the ultrasound is activated, the microbubbles explode like smart and targeted warheads, creating holes in cancer cells' […]
June 22, 2020

Evolutionary key for a bigger brain

The expansion of the human brain during evolution, specifically of the neocortex, is linked to our cognitive abilities such as reasoning and language. Researchers at the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) in Dresden have been studying a gene called ARHGAP11B for many years. This gene […]
June 22, 2020

Blood test to monitor cancer up to ten times more sensitive than current methods

A new method of analysing cancer patients’ blood for evidence of the disease could be up to ten times more sensitive than previous methods according to new research led by the University of Cambridge. In the coming years, this method and others based on this approach could lead to tests […]