Related Science News – Page 4 – Innovita Research

Related Science News

March 29, 2021

ORNL meets key FDA milestone for cancer-fighting Ac-225 isotope

A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs. The U.S. Food and Drug Administration recently acknowledged receipt of Oak Ridge National Laboratory’s drug master file for actinium-225 nitrate, which enables pharmaceutical companies to reference the document to […]
March 28, 2021

Common Alzheimer’s treatment linked to slower cognitive decline

Cholinesterase inhibitors are a group of drugs recommended for the treatment of Alzheimer’s disease, but their effects on cognition have been debated and few studies have investigated their long-term effects. A new study involving researchers from Karolinska Institutet and published in the journal Neurology shows persisting cognitive benefits and reduced […]
March 28, 2021

World-first clinical trial targets immune molecule IL23 as potential treatment for sarcoma

Sydney researchers are testing whether an existing medication could be repurposed to treat sarcoma. Recruitment is now open for a national clinical trial that will test whether an existing therapy for psoriasis can help treat patients with sarcomas, which are rare cancers arising in the connective tissues (bone, muscle, tendons, […]
March 27, 2021

New Clues to Classic Cancer Target Found in Immune Cells

New clues to a long-pursued drug target in cancer may reside within immune cells, researchers at the University of Michigan Rogel Cancer Center have discovered. The findings, which appear in Nature Immunology, not only shed new light on cancer immunology, they also suggest clinical trials related to this key target — an interaction that […]
March 27, 2021

Engineered immune cells deliver anticancer signal, prevent cancer from spreading

Scientists have genetically engineered immune cells, called myeloid cells, to precisely deliver an anticancer signal to organs where cancer may spread. In a study of mice, treatment with the engineered cells shrank tumors and prevented the cancer from spreading to other parts of the body. The study, led by scientists […]
March 27, 2021

DNA damage “hot spots” discovered within neurons

Researchers at the National Institutes of Health (NIH) have discovered specific regions within the DNA of neurons that accumulate a certain type of damage (called single-strand breaks or SSBs). This accumulation of SSBs appears to be unique to neurons, and it challenges what is generally understood about the cause of […]
March 27, 2021

Research Group Identifies Potential Therapeutic Target for Lupus

A recent study published in JCI found that a neutrophil’s endoplasmic reticulum, the organelle that normally makes proteins in the cell, becomes stressed in the autoimmune disorder lupus. This stress activates a molecule called IRE1α, which appears to play a critical role in lupus pathogenesis in mice. A multidisciplinary research group at the University […]
March 27, 2021

Preparing for exascale: Aurora supercomputer to help scientists visualize the spread of cancer

Scientists are preparing a cancer modeling study to run on Argonne’s upcoming Aurora supercomputer before it goes online in 2022. The U.S. Department of Energy’s (DOE) Argonne National Laboratory will be home to one of the nation’s first exascale supercomputers when Aurora arrives in 2022. To prepare codes for the architecture and scale of […]
March 27, 2021

Research reveals how the brain inhibits remyelination in MS and how to treat it

Two papers by University at Buffalo researchers reveal important new findings as to how regeneration of myelin in multiple sclerosis fails and, potentially, more efficient ways to treat it. The findings include the first demonstration that an existing drug, currently being studied as a cancer therapy, can alter key signalling […]
March 27, 2021

Predicting when epileptic seizures will happen

Epileptics, listen up: imagine being able to have a “weather forecast for your brain,” a way to get advance of the onset of your next seizure, thanks to a microchip planted under your scalp. Science fiction, you think? Not for two researchers at the Centre hospitalier de l’Université de Montréal […]
March 27, 2021

How cells transport molecules with ‘active carpets’

New research provides insights into the process of diffusion in living systems, with implications from novel active coatings to understanding how pathogens are cleared from lungs. A drop of food colouring slowly spreading in a glass of water is driven by a process known as diffusion. While the mathematics of […]
March 27, 2021

Study finds evidence of Bartonella infection in schizophrenia patients

A new study led by University of Wisconsin–Madison School of Veterinary Medicine professor Erin Lashnits shows evidence of Bartonella infection in the blood of people with schizophrenia and schizoaffective disorder. “Researchers have been looking at the connection between bacterial infection and neuropsychiatric disease for some time,” Lashnits says in a news release by North Carolina […]
March 26, 2021

Quantitative Detection of Fatty Liver Disease by Assessing Fat Distribution in the Liver

Excessive fat accumulation in the liver can lead to serious medical problems, including liver failure. Thus, understanding the distribution of lipids within the liver is a critical step in diagnosing fatty liver diseases. A team of researchers at Tokyo University of Science has now shown that near-infrared hyperspectral imaging permits […]
March 26, 2021

Study finds diet high in poor quality carbohydrates increases heart disease and death

A large study of people living on five continents, led by researchers at McMaster University and the University of Toronto, has found a diet high in poor quality carbohydrates leads to a higher risk of heart attacks, strokes, and death. The higher risks of a diet high in poor quality […]
March 26, 2021

Gene changes linked to severe repetitive behaviors

Graybiel lab identifies genes linked to abnormal repetitive behaviors often seen in models of addiction and schizophrenia. Extreme repetitive behaviors such as hand-flapping, body-rocking, skin-picking, and sniffing are common to a number of brain disorders including autism, schizophrenia, Huntington’s disease, and drug addiction. These behaviors, termed stereotypies, are also apparent in animal models […]
March 26, 2021

How human cells coordinate the start of DNA replication

Cold Spring Harbor Laboratory (CSHL) President and CEO Bruce Stillman have been dissecting DNA replication, a critical step in cell division, since the 1980s. His lab studies how Origin Recognition Complexes—ORCs—coordinate DNA duplication. They discovered how our cells assemble and disassemble ORCs during the cell division cycle. One ORC protein is sequestered […]
March 26, 2021

A remote device helps medical staff in the fight against time

‘We noticed that the patient monitoring processes in hospitals are inefficient. They also lack digital solutions and generate unnecessary manual and administrative tasks for the overworked nurses and doctors.’ says Miklós Knebel. Knebel and Péter Dános participated in a project run by EIT Digital Master School in which students designed a new type […]
March 26, 2021

Meconium may provide clues to fetal-alcohol exposure, forecast behavioral issues later in childhood

Newborn babies with indicators of alcohol in their stool are more likely to face behavioral difficulties later in childhood, according to new study from a team of multi-disciplinary researchers at Case Western Reserve University. The research, published recently in the Journal of Drug and Alcohol Dependence, suggests that a biomarker at birth […]
March 26, 2021

Study Reveals Frequency and Characteristics of Stroke in COVID-19 Patients

A review of nearly 28,000 emergency department records shows less than 2% of patients diagnosed with COVID-19 suffered an ischemic stroke but those who did had an increased risk of requiring long-term care after hospital discharge. Those are the findings from a study conducted by researchers from the University of Missouri […]
March 26, 2021

Sleep study discovery could hold key to tackling PTSD and other anxiety disorders

Triggering‌ ‌bad‌ ‌memories‌ ‌to‌ ‌reactivate‌ ‌in‌ ‌REM‌ ‌sleep‌ ‌–‌ ‌the‌ ‌period‌ ‌when‌ ‌people‌ ‌dream‌ ‌most‌ ‌vividly‌ ‌–‌ ‌reduces‌ ‌the‌ ‌emotion‌ ‌associated‌ ‌with‌ ‌these‌ ‌memories‌ ‌on‌ ‌waking,‌ ‌a‌ ‌new‌ ‌study‌ ‌has‌ ‌suggested.‌ ‌ It‌ ‌is‌ ‌the‌ ‌first‌ ‌research‌ ‌to‌ ‌suggest‌ ‌this‌ ‌technique‌ ‌could‌ ‌have‌ ‌the potential‌ ‌for‌ ‌use‌ ‌as‌ ‌a‌ ‌tool‌ ‌for‌ ‌the‌ […]
March 26, 2021

Engineered immune cells deliver anticancer signal, prevent cancer from spreading

In a study of mice, treatment with the engineered cells shrank tumors and prevented the cancer from spreading to other parts of the body. Scientists have genetically engineered immune cells, called myeloid cells, to precisely deliver an anticancer signal to organs where cancer may spread. In a study of mice, […]
March 26, 2021

Key research advance could spawn new treatments for heart diseases

Scientists peering into the beating heart have solved a decades-old, fundamental mystery about how the heart works. The revelation could herald the development of new treatments for heart diseases — the leading cause of death worldwide. Researchers from Eastern Virginia Medical School, Florida State University and the University of Virginia […]
March 26, 2021

Should you take fish oil? Depends on your genotype

Fish oil supplements are a billion-dollar industry built on a foundation of purported, but not proven, health benefits. Now, new research from a team led by a University of Georgia scientist indicates that taking fish oil only provides health benefits if you have the right genetic makeup. The study, led by Kaixiong Ye […]
March 25, 2021

Higher Cardiovascular Health Score Correlates with Lower Epigenetic Age Acceleration

Epigenetic age acceleration is the degree to which epigenetic age is higher than chronological age. Epigenetic age is assessed via one of the epigenetic clocks, measuring the status of DNA methylation at numerous CpG sites on the genome. Some changes in DNA methylation patterns are characteristic of aging, a reaction […]
March 25, 2021

Evolution drives autism and other conditions to occur much more frequently in boys and men

Evolutionary forces drive a glaring gender imbalance in the occurrence of many health conditions, including autism, a team of genetics researchers has concluded. The human genome has evolved to favour the inheritance of very different characteristics in males and females, which in turn makes men more vulnerable to a host […]
March 25, 2021

BMI1, a promising gene to protect against Alzheimer's disease

Another step towards understanding Alzheimer's disease has been taken at the Maisonneuve-Rosemont Hospital Research Centre. Molecular biologist  Gilbert Bernier, and professor of neurosciences at Université de Montréal, has discovered a new function for the BMI1 gene, which is known to inhibit brain ageing. The results of his work have just been […]
March 25, 2021

Zika virus helps destroy deadly brain cancer in mice

The Zika virus that ravaged the Americas, leaving many babies with permanent brain damage, may have a silver lining. The virus can activate immune cells to destroy an aggressive brain cancer in mice, giving a powerful boost to an immunotherapy drug and sparking long-lasting immunological memory that can ward off […]
March 24, 2021

Epidemiological Evidence for Herpesvirus Infection to Increase the Risk of Alzheimer's Disease

There is much debate these days over the contribution of persistent infection (such as by herpesviruses) to the development of Alzheimer's disease. Not everyone with the evident risk factors, such as obesity, frailty, chronic inflammation, and so forth, progresses from mild cognitive impairment to full blown Alzheimer's disease. Why is […]
March 24, 2021

Two servings of fish per week helps prevent recurrent heart disease

An analysis of several large studies involving participants from more than 60 countries, spearheaded by researchers from McMaster University, has found that eating oily fish regularly can help prevent cardiovascular disease (CVD) in high-risk individuals, such as those who already have heart disease or stroke. The critical ingredient is omega-3 […]
March 24, 2021

Probiotics increase gut bacteria diversity in extremely preterm infants

Extremely preterm infants can suffer from a life-threatening inflammation of the gut. A new clinical study has shown that supplements of a lactic acid bacterium may have positive effects by increasing the diversity of intestinal bacteria in these infants. The study has been published in the scientific journal Cell Reports […]