Related Science News – Page 6 – Innovita Research

Related Science News

June 19, 2019

Special fibroblasts help pancreatic cancer cells evade immune detection

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related deaths in the world. Mostly chemoresistant, PDAC so far has no effective treatment. Understanding the connective tissue, called stroma, that surrounds, nurtures, and even protects PDAC tumors, is key to developing effective therapeutics. “PDAC patients are diagnosed really late, so […]
June 19, 2019

Anti-inflammation approach shows promise for preventing cancer metastasis

An anti-inflammatory drug called ketorolac, given before surgery, can promote long-term survival in animal models of cancer metastasis, a team of scientists has found. Furthermore, so-called “pro-resolution” therapies can also trigger the immune system to eliminate metastatic cells. The research also suggests that flanking chemotherapy with anti-inflammatory drugs can unleash […]
June 19, 2019

Rutgers Scientist Creates “Virtual Biopsy” Device to Detect Skin Tumors

Using sound vibrations and pulses of near-infrared light, a Rutgers University scientist has developed a new “virtual biopsy” device that can quickly determine a skin lesion’s depth and potential malignancy without using a scalpel. The ability to analyze a skin tumor non-invasively could make biopsies much less risky and distressing […]
June 19, 2019

Cancer vaccine on its way? Scientists confirm nan­o­vac­cines are safe, well tol­er­ated and effective

Immunotherapy is going to be the next big thing in cancer treatment. Someday cancer will be stopped at its tracks by drugs that could be essentially called vaccines. Scientists at the University of Helsinki developed porous silicon and adenovirus-based biohybrid nanovaccines that are safe, well tol­er­ated, and effective. Immunotherapy is […]
June 18, 2019

Waking up early increases the risk of death, but not for everyone

Our modern world is moving at an incredible pace. This means that we also have to hustle. Many people are waking up with a sound of an alarm clock, sometimes incredibly early. But is it healthy? Scientists from UCL conducted a study looking at sleep and mortality from across different […]
June 18, 2019

Deleting Old Cells

New research from Harvard Medical School researchers at Joslin Diabetes Center has shown that insulin resistance in mice increases the proportion of dysfunctional aged beta cells. Such an increase in aged beta cells could lead to type 2 diabetes. The researchers then confirmed a similarly increased proportion of aged beta […]
June 18, 2019

Immune system can slow degenerative eye disease, NIH-led mouse study shows

A new study shows that the complement system, part of the innate immune system, plays a protective role to slow retinal degeneration in a mouse model of retinitis pigmentosa, an inherited eye disease. This surprising discovery contradicts previous studies of other eye diseases suggesting that the complement system worsens retinal […]
June 18, 2019

Aging delayed in older mice given blood component from young mice

New research has identified a novel approach to staving off the detrimental effects of aging, according to a study from Washington University School of Medicine in St. Louis. The study suggests that a protein that is abundant in the blood of young mice plays a vital role in keeping mice […]
June 18, 2019

Antioxidant puts up fight, but loses battle against toxic protein linked to Alzheimer’s disease

New research may explain why an antioxidant that protects the brain is also associated with deterioration in areas susceptible to Alzheimer’s disease. The antioxidant, superoxide dismutase or SOD1, improves cognition by fighting off free radicals that cause oxidative damage in the brain. However, an Iowa State University research team found […]
June 17, 2019

Suicide among older adults in long-term care suggests more is needed to promote mental, social well-being

Clinicians, administrators and policymakers should consider ways to support the mental health and well-being of older adults as they go through residential transitions, according to a University of Michigan study that looked at deaths by suicide among people 55 and older. The study focuses on suicides among adults who were […]
June 17, 2019

Study seeks to expand treatment options for rare airway disease

Armed with $1.2 million in funding from the National Heart, Lung and Blood Institute (NHLBI), researchers at Vanderbilt University Medical Center are searching to understand the cause of a rare airway disease in hopes of developing better treatments. Idiopathic subglottic stenosis (iSGS) is an unexplained narrowing of the windpipe just […]
June 17, 2019

People with Untreated “White Coat Hypertension” Twice as Likely to Die from Heart Disease

White coat hypertension, a condition in which a patient’s blood pressure readings are higher when taken at the doctor’s office compared to other settings, was originally attributed to the anxiety patients might experience during medical appointments. However, over the years, research has suggested the elevated readings might be a sign […]
June 17, 2019

VR slow training for a future without falls

An elderly woman balances on one leg while watching a television display. What do you think she’s doing? She’s actually in the midst of using virtual reality (VR) technology for slow training. While Japan is leading the world in terms of a superaging society, the problem is the big gap […]
June 17, 2019

Altered brain activity in antisocial girls – new study

Teenage girls with severe antisocial behaviour display reduced brain activity and weaker connectivity between the brain regions implicated in emotion regulation, according to a new study involving researchers from the University's Department of Psychology. The findings, published in the journal Biological Psychiatry, offer a neurobiological explanation for the difficulties some girls […]
June 17, 2019

Researchers’ discovery could lead to improved therapies for Duchenne muscular dystrophy

A new multi-institution study spearheaded by researchers at Florida State University and the University of California, Los Angeles suggests a tiny protein could play a major role in combating heart failure related to Duchenne muscular dystrophy (DMD), the most common lethal genetic disorder among children. In collaboration with scientists from […]
June 14, 2019

Causal association between excess body fat and cardiovascular disease

Using a method called Mendelian randomisation, researchers at Karolinska Institutet show that there is a causal association between high BMI and several heart and blood vessel diseases, especially if the fat mass is high. The greatest risk increase was observed for a condition known as aortic valve stenosis. The study […]
June 14, 2019

Rheumatoid arthritic pain could be caused by antibodies

Antibodies that exist in the joints before the onset of rheumatoid arthritis can cause pain even in the absence of arthritis, researchers from Karolinska Institutet in Sweden report. The researchers believe that the finding, which is published in the Journal of Experimental Medicine, can represent a general mechanism in autoimmunity […]
June 14, 2019

Lower Risk of Type 1 Diabetes in Children Vaccinated Against ‘Stomach Flu’ Virus

Vaccinating babies against a virus that causes childhood “stomach flu” greatly reduces their chance of getting so sick that they need hospital care, a new study shows. But the University of Michigan study also reveals a surprise: Being fully vaccinated against rotavirus in the first months of life is associated […]
June 14, 2019

Scientists Slow Progression of Debilitating Neurodegenerative Disorder

An international study led by scientists in Oakland, Calif., and Munich, Germany, may offer hope to children and adults with a rare and debilitating genetic disorder, Pantothenate Kinase-associated neurodegeneration (PKAN), as well as a potentially new approach to treat other neurodegenerative disorders, such as Alzheimer’s, Parkinson’s disease and multiple sclerosis. […]
June 14, 2019

Any which way: Flies go all-in to overcome defect, reach adulthood

New research from the University of Nebraska-Lincoln has revealed how fruit fly larvae with a seemingly fatal flaw can survive and advance to adulthood. As in all multicellular organisms, both the nuclei and mitochondria of fruit fly cells contain distinct DNA. Those two genomes include complementary instruction manuals for collectively […]
June 13, 2019

Get them moving before kindergarten

Physical activity in early childhood may have an impact on cardiovascular health later in life, according to new research from McMaster, where scientists followed the activity levels of hundreds of preschoolers over a period of years. They found that physical activity in children as young as three years old benefits […]
June 13, 2019

New Discovery could Rewrite Textbooks on Evolutionary Theory

With the publication of a new study in the leading scientific journal Nature, a group of researchers from the University of Queensland may have overturned the way scientists think of the evolution of animals on Earth. Thanks to advanced technology, the group was able to make an intuitive, yet unexpected […]
June 13, 2019

A homing beacon for chemotherapy drugs

Killing tumor cells while sparing their normal counterparts is a central challenge of cancer chemotherapy. If scientists could put a “homing beacon” in tumors, they could attract these medicines and reduce side effects caused by the drugs acting on healthy cells. Now, researchers have made a hydrogel that, when injected […]
June 13, 2019

NIH-developed technique prevents obstruction in heart valve replacement

A novel technique has proven successful in preventing coronary artery obstruction during transcatheter aortic valve replacement (TAVR), a rare but often fatal complication. Called Bioprosthetic Aortic Scallop Intentional Laceration to prevent Iatrogenic Coronary Artery obstruction (BASILICA), the technique will increase treatment options for high-risk patients who need heart valve procedures. […]
June 13, 2019

A microscopic topographic map of cellular function

A decade of research leads MU scientists to a better understanding of how materials move out of cells. The flow of traffic through our nation’s highways and byways is meticulously mapped and studied, but less is known about how materials in cells travel. Now, a team of researchers at the University […]
June 13, 2019

Immunotherapy Drug Shows Potential to Cure Advanced Lung Cancer

In a new study including Yale Cancer Center and Smilow Cancer Hospital researchers, the cancer immunotherapy drug pembrolizumab (Keytruda), increased survival for patients with advanced non-small cell lung cancer (NSCLC), a disease once considered an aggressive, and uniformly fatal cancer. The findings were presented at the American Society of Clinical […]
June 13, 2019

Study: unhealthy gut promotes spread of breast cancer

An unhealthy, inflamed gut causes breast cancer to become much more invasive and spread more quickly to other parts of the body, new research from the University of Virginia Cancer Center suggests. Melanie Rutkowski, a research faculty member in UVA’s Department of Microbiology, Immunology and Cancer Biology, found that disrupting the […]
June 12, 2019

New gene-editing system precisely inserts large DNA sequences into cellular DNA

Researchers identify and develop new CRISPR-associated transposase system for targeted integration of DNA, adding key capabilities to gene-editing technology. A team led by researchers from Broad Institute of MIT and Harvard, and the McGovern Institute for Brain Research at MIT, has characterized and engineered a new gene-editing system that can precisely and […]
June 12, 2019

Cause of hardening of the arteries – and potential treatment – identified

A team of UK scientists have identified the mechanism behind hardening of the arteries, and shown in animal studies that a generic medication normally used to treat acne could be an effective treatment for the condition. The team, led by the University of Cambridge and King’s College London, found that […]
June 12, 2019

Gene mutations are pointing towards the root causes of the multiple sclerosis

Multiple sclerosis is a disease, which is characterized by the insulating covers of nerve cells in the brain and spinal cord. There is no cure and existing treatments can have tremendous side effects. Eventually MS leads to disability. Now an international team of scientists led by the University of British […]