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December 29, 2021

What is Known of the Reasons Why Aging Stem Cells Lose their Regenerative Capacity

Declining stem cell function is undoubtedly an important contribution to degenerative aging and age-related mortality. Tissues require the supply of new somatic cells that is generated by stem cells in order to replace losses, repair damage, and maintain function. Unlike stem cells, somatic cells are limited in the number of […]
December 28, 2021

Senolytic Treatment Improves Muscle Regeneration in Old Mice Only

Senescent cells accumulate with age. Researchers here provide evidence for yet another age-related decline to be added to the long list of issues in which this accumulation of senescent cells is an important contributing cause. In this case, the problem is the loss of regenerative capacity in muscle tissue that […]