Related Science News – Page 171 – Innovita Research

Related Science News

August 25, 2020

Taking Risks for Big Rewards

Much of the world, including research at Penn Medicine, has focused its attention on how T cells — which play a central role in immune response — might shape the trajectory of COVID-19 infection, and how immunotherapy can shed light on treatment of the disease. Already a leader in immunotherapy research […]
August 24, 2020

New maps of chemical marks on DNA pinpoint regions relevant to many developmental diseases

Salk researchers mapped how DNA methylation changes over time in mice to better understand developmental disorders. In research that aims to illuminate the causes of human developmental disorders, Salk scientists have generated 168 new maps of chemical marks on strands of DNA—called methylation—in developing mice. The data, published July 29, […]
August 24, 2020

Genetic study points to cells responsible for Parkinson’s disease

Scientists have uncovered new insights into the origins of Parkinson’s disease. The team, from the UK Dementia Research Institute at Cardiff University and the Oxford Parkinson’s Disease Centre, University of Oxford, studied the genes of more than 6,000 cells from a region deep in the middle of the brain called the […]
August 24, 2020

Heart attack damage reduced by shielded stem cells

Bioengineers and surgeons from Rice University and Baylor College of Medicine (BCM) have shown that shielding stem cells with a novel biomaterial improve the cells’ ability to heal heart injuries caused by heart attacks. In a study using rodents, a team led by Rice’s Omid Veiseh and Baylor’s Ravi Ghanta showed it could […]
August 22, 2020

Alzheimer's risk can be predicted as early as teenage years

Alzheimer’s disease is a debilitating condition that is going to touch millions of aging people. It is incurable, even if treatment options are slowly getting better. Early start on these treatments is probably the best bet, but how can you predict that the person is going to develop Alzheimer’s before […]
August 21, 2020

Studying how skin cancer starts

Luis Ortiz-Rodríguez grew up on the beaches of Puerto Rico—surfing, swimming, and running in the hot sand—and swears he had never put on sunblock a day in his life. Then the day came when he peered through an ultrafast laser spectrometer at the College of Arts & Sciences and observed […]
August 21, 2020

New 'molecular computers' find the right cells

Scientists have demonstrated a new way to precisely target cells by distinguishing them from neighboring cells that look quite similar. Even cells that become cancerous may differ from their healthy neighbors in only a few subtle ways. A central challenge in the treatment of cancer and many other diseases is […]
August 20, 2020

The Gut Microbiome Changes Shortly Before Death in Centenarians

Extremely old people have such high mortality rates that studies such as this one here become practical, answering the question of how the gut microbiome changes in the final decline into death. It is well established that the gut microbiome is influential on health, and undergoes detrimental changes across the […]
August 20, 2020

Immunotherapy extends survival in mouse model of hard-to-treat breast cancer

Immunotherapies for cancer — treatments that prime the immune system to attack tumors — are valuable weapons in the anti-cancer arsenal. But some cancers are more difficult to target with this strategy than others. Today, scientists report a new type of immunotherapy that dramatically extends the survival of mice that […]
August 20, 2020

Researchers find method to regrow cartilage in the joints

Researchers at the Stanford University School of Medicine have discovered a way to regenerate, in mice and human tissue, the cushion of cartilage found in joints. Loss of this slippery and shock-absorbing tissue layer, called articular cartilage, is responsible for many cases of joint pain and arthritis, which afflicts more than 55 […]
August 20, 2020

Researchers find way to speed up nerve regrowth for trauma patients

Electrical stimulation a week before surgery causes nerves to regenerate three to five times faster, leading to better outcomes. A University of Alberta researcher has found a treatment that increases the speed of nerve regeneration by three to five times, leading to much better outcomes for trauma surgery patients. “We […]
August 20, 2020

Genetic background may affect adaptions to aging

How we adapt to aging late in life may be genetically influenced, according to a study led by a psychologist at the University of California, Riverside. The research, published in Aging Cell, has implications for how epigenetic factors related to aging. Epigenesis is a process in which chemicals attached to DNA […]
August 20, 2020

Iron-mediated cancer cell activity: a new regulation mechanism

CNRS researchers at the Institut Curie have recently shown that cancer cells use a membrane protein that has been known for several decades to internalise iron. Published in Nature Chemistry (August 3rd, 2020), this work shows that the absorbed iron allows cancer cells to acquire metastatic properties. Biologists knew CD44 […]
August 19, 2020

Reducing LDL Cholesterol is the Wrong Target for Cardiovascular Disease

When people say “cardiovascular disease” in the context of blood cholesterol, they mean atherosclerosis. This is the name given to the build up of fatty deposits that narrow and weaken blood vessels, leading to heart failure and ultimately some form of disabling or fatal rupture – a stroke or heart […]
August 19, 2020

Drugs against alpha-ketoglutarate may combat deadly childhood brain tumor

Every year, 150 to 300 children in the United States are diagnosed with diffuse intrinsic pontine gliomas (DIPGs), aggressive and lethal tumors that grow deep inside the brain, for which there are no cures. In a study funded by the National Institutes of Health, researchers showed that experimental drugs designed to […]
August 19, 2020

NIH study suggests opioid use linked to pregnancy loss, lower chance of conception

Opioid use among women trying to conceive may be associated with a lower chance of pregnancy, suggests a National Institutes of Health study. Moreover, opioid use in early pregnancy may be associated with a greater chance of pregnancy loss. The study appears in Epidemiology. “Our findings indicate that women who […]
August 19, 2020

Genomics data to enable critical brain and mitochondrial research

A Garvan-developed platform is providing researchers access to genomic data that will help drive discoveries in severe mitochondrial and brain disorders. Medical researchers from across the globe will gain new insight into some of the most devastating inherited conditions, thanks to anonymized genomic and clinical summary data made available by […]
August 18, 2020

Cell diversity in the embryo

A research team at the Max Planck Institute for Molecular Genetics in Berlin has explored the role of factors in embryonic development that do not alter the sequence of DNA, but only epigenetically modify its “packaging”. In the scientific journal Nature, they describe how regulatory mechanisms contribute to the formation of […]
August 18, 2020

Four-stranded DNA structures found to play role in breast cancer

Four-stranded DNA structures – known as G-quadruplexes – have been shown to play a role in certain types of breast cancer for the first time, providing a potential new target for personalised medicine, say scientists at the University of Cambridge. In 1953, Cambridge researchers Francis Crick and James Watson co-authored […]
August 18, 2020

The behaviour of therapeutic antibodies in immunotherapy

Since the late 1990s, immunotherapy has been the frontline treatment against lymphomas where synthetic antibodies are used to stop the proliferation of cancerous white blood cells. However, in the more than 20 years since their use began, the molecular mechanisms that underlie this therapy are still little understood. For the […]
August 18, 2020

Flipping a Metabolic Switch to Slow Tumor Growth

The enzyme serine palmitoyl-transferase can be used as a metabolically responsive switch that decreases tumor growth, according to a new study by a team of San Diego scientists, who published their findings in the journal Nature. By restricting the dietary amino acids serine and glycine, or pharmacologically targeting the serine […]
August 18, 2020

Extrachromosomal DNA is common in human cancer and drives poor patient outcomes

The multiplication of genes located in extrachromosomal DNA that have the potential to cause cancer drives poor patient outcomes across many cancer types, according to a Nature Genetics study published by a team of researchers including Professors Vineet Bafna and Dr. Paul Mischel of the University of California San Diego  […]
August 18, 2020

Should Rapamycin be Prescribed Ubiquitously as an Anti-Aging Supplement?

Should rapamycin be prescribed ubiquitously as an anti-aging supplement? That is the question the authors of this commentary ask after a short overview of what is known of the beneficial effects of rapamycin on mechanisms relevant to aging. Research into inhibition of the two mTOR complexes, mTORC1 and mTORC2, via […]
August 18, 2020

Gene targeting helps overcome the resistance of brain cancer to therapy

New insight into a gene that controls energy production in cancer stem cells could help in the search for a more effective treatment for glioblastoma. A McGill-led study published in Nature Communications reveals that suppressing the OSMR gene can improve the effectiveness of radiation therapy. This approach, led by the laboratory of […]
August 18, 2020

Autism-Cholesterol Link

New research reveals a subtype of autism associated with lipid abnormalities. Researchers at Harvard Medical School, Massachusetts Institute of Technology and Northwestern University have identified a subtype of autism arising from a cluster of genes that regulate cholesterol metabolism and brain development. The researchers say their findings, published in Nature […]
August 18, 2020

New pediatric sleep disorder defined

Children suffering from restless sleep disorder would report trouble focusing during the day, and emotional and behavioral problems at home and school. A UW Medicine researcher, along with colleagues from Italy, Spain and Chile, have defined a new pediatric sleep disorder, which once diagnosed and treated, may help children and […]