Related Science News – Page 9 – Innovita Research

Related Science News

January 21, 2021

New discovery in breast cancer treatment

Liverpool cancer researchers have contributed to important new findings of the positive role of androgens in breast cancer treatment, with immediate implications for women with oestrogen receptor-positive (ER-positive) advanced disease. ER-positive breast cancer is the most common type of breast cancer diagnosed today, accounting for around 75 out of every […]
January 21, 2021

Target of new cancer treatment valid for breast as well as blood cancers: study

One more piece of the puzzle has fallen into place behind a new drug whose anti-cancer potential was developed at the University of Alberta and is set to begin human trials this year, thanks to newly published research. “The results provide more justification and rationale for starting the clinical trial in […]
January 20, 2021

Assessing Technology of Cellular Senescence with Minimally Invasive Sampling Technique

NineSigma, representing Suntory Global Innovation Center Ltd. (“Client”), which serves as the Suntory Group's basic research department, seeks technologies for making a minimally invasive assessment of cellular senescence in the human clinical setting. The Client has in mind biomarker-based assessment methods but welcomes proposals for a wide range of other approaches. Anti-ageing is […]
January 20, 2021

New discovery in breast cancer treatment

Researchers at the University of Adelaide have found new evidence about the positive role of androgens in breast cancer treatment with immediate implications for women with estrogen receptor-driven metastatic disease. Published in Nature Medicine, the international study conducted in collaboration with the Garvan Institute of Medical Research, looked at the […]
January 20, 2021

New Treatment Target Discovered That Halts Osteoarthritis-Like Knee Cartilage Degeneration

There is currently no cure for osteoarthritis, but a group of scientists believe they’ve discovered a method through which a simple knee injection could potentially stop the disease’s effects. These researchers showed that they could target a specific protein pathway in mice, put it into overdrive and halt cartilage degeneration […]
January 20, 2021

Fatty acid may help combat multiple sclerosis

The abnormal immune system response that causes multiple sclerosis (MS) by attacking and damaging the central nervous system can be triggered by the lack of a specific fatty acid in fat tissue, according to a new Yale study. The finding suggests that dietary change might help treat some people with […]
January 19, 2021

An Example of High Dose Fisetin Exhibiting Senolytic Effects in Mice

Fisetin is perhaps the most intriguing of the first generation senolytic compounds, those capable of selectively destroying senescent cells in old tissues and thus producing rejuvenation to a meaningful degree. Senolytics have been demonstrated in animal studies to reverse many age-related conditions to a greater degree than any other approaches. […]
January 19, 2021

Researchers use lasers and molecular tethers to create perfectly patterned platforms for tissue engineering

Imagine going to a surgeon to have a diseased or injured organ switched out for a fully functional, laboratory-grown replacement. This remains science fiction and not reality because researchers today struggle to organize cells into the complex 3D arrangements that our bodies can master on their own. There are two […]
January 19, 2021

A mathematical study describes how metastasis starts

A scientific study carried out by the Universidad Carlos III de Madrid (UC3M) and the Universidad Complutense de Madrid (UCM) has produced a mathematical description of the way in which a tumour invades the epithelial cells and automatically quantifies the progression of the tumour and the remaining cell islands after […]
January 19, 2021

Genetic factors involved in shaping the composition of the human gut microbiome, finds international research team

Human genes have an impact on shaping our gut ecosystem according to new evidence from the international MIBioGen consortium study involving more than 18,000 people. The findings, led by the University Medical Center Groningen, Netherlands and involving researchers at the University of Bristol, are published today [18 January] in Nature […]
January 19, 2021

The immune system mounts a lasting defense after recovery from COVID-19

As the number of people who have fought off SARS-CoV-2 climbs ever higher, a critical question has grown in importance: How long will their immunity to the novel coronavirus last? A new Rockefeller study offers an encouraging answer, suggesting that those who recover from COVID-19 are protected against the virus […]
January 19, 2021

Personalized Brain Stimulation Alleviates Severe Depression Symptoms

Targeted neuromodulation tailored to individual patients’ distinctive symptoms is an increasingly common way of correcting misfiring brain circuits in people with epilepsy or Parkinson’s disease. Now, scientists at UC San Francisco’s Dolby Family Center for Mood Disorders and Weill Institute for Neurosciences have demonstrated a novel personalized neuromodulation approach that – at least in […]
January 19, 2021

Where do our minds wander? Brain waves can point the way

Anyone who has tried and failed to meditate knows that our minds are rarely still. But where do they roam? New research led by UC Berkeley has come up with a way to track the flow of our internal thought processes and signal whether our minds are focused, fixated or […]
January 18, 2021

Arterial Stiffening with Age Correlates with Structural Damage to the Brain

Today's open access research paper is a reminder of one of the more direct mechanistic links between vascular aging and brain aging. Blood vessels stiffen with age, becoming progressively worse at the necessary task of contracting and relaxing in response to circumstances. This is in part due to cross-linking in […]
January 18, 2021

Acute itching in eczema patients linked to environmental allergens

In addition to a skin rash, many eczema sufferers also experience chronic itching, but sometimes that itching can become torturous. Worse, antihistamines — the standard treatment for itching and allergy — often don’t help. New research from Washington University School of Medicine in St. Louis indicates that allergens in the environment often […]
January 18, 2021

UNH Researchers Discover New Inhibitor Drug Combination for Rare Form of Cancer

Waldenström macroglobulinemia (WM), a rare form of lymphoma, does not have any known cure and only one FDA-approved treatment making it challenging to treat patients. Researchers at the University of New Hampshire took the novel approach of targeting specific cell proteins that control DNA information using inhibitors, or drugs, that […]
January 17, 2021

Moonshots for the Treatment of Aging: Less Incrementalism, More Ambition

There is far too much incrementalism in the present research and development of therapies to treat aging. Much of the field is engaged in mimicking calorie restriction or repurposing existing drugs that were found to increase mouse life span by a few percentage points. This will not meaningfully change the […]
January 17, 2021

Why cancer cells waste so much energy

In the 1920s, German chemist Otto Warburg discovered that cancer cells don’t metabolize sugar the same way that healthy cells usually do. Since then, scientists have tried to figure out why cancer cells use this alternative pathway, which is much less efficient. MIT biologists have now found a possible answer […]
January 17, 2021

Artificial intelligence tool for reading MRI scans could transform prostate cancer surgery and treatment

Researchers at the Center for Computational Imaging and Personalized Diagnostics (CCIPD) at Case Western Reserve University have preliminarily validated an artificial intelligence (AI) tool to predict how likely the disease is to recur following surgical treatment for prostate cancer. The tool, called RadClip, uses AI algorithms to examine a variety of data, […]
January 16, 2021

Tackling rare genetic diseases with own genome editing technology

Haruhiko Morita had never aspired to be an entrepreneur, but his astute foresight was instrumental in landing his current position of a chief executive officer at Modalis Therapeutics Corp. In the late 1980s and early 1990s, while Morita was an undergraduate and graduate student at the Faculty of Engineering and […]
January 16, 2021

Frail Older Individuals Exhibit a Worse Response to Vaccination

Frailty is usually accompanied by greater immune dysfunction, given that chronic inflammation is a strong component of both immune aging and the various dysfunctions of frailty. Thus frail individuals exhibit a worse response to vaccinations intended to prevent infectious disease. This is unfortunate, as this is the population in greatest […]
January 16, 2021

U of A research offers insights into how people cope with chronic back pain

Chronic back pain can keep us from living our best lives, but a University of Alberta study shows why some people don’t let it stop them. The research, published in the Journal of Occupational Rehabilitation, sheds light on what motivates people to soldier through their persistent pain. The qualitative study is one […]
January 16, 2021

Motor Control

New tool reveals details about motor neuron circuitry in fruit flies. How do networks of neurons connect to form functional circuits? To address this long-standing question in neuroscience, researchers from Boston Children's Hospital and Harvard Medical School have developed a new pipeline to study neural circuits and, in the process, […]
January 15, 2021

Renaissance molecule – dopamine and its multiplicative role in the organism

Dopamine is one of the essential neurotransmitters in the brain. Its action is limited to the brain; it acts as a chemical messenger throughout the body. Dopamine stimulates the cardiovascular system's work and is responsible for cognitive abilities, coordination of movements, and even feelings. Here, we will try to explain […]
January 15, 2021

New computational method detects disrupted pathways in cancer

Cancer is a notoriously complex disease, in part because it may be caused by mutations among hundreds or even thousands of genes. In addition, most cancers exhibit an extraordinary amount of variation among genetic mutations, even between patients with the same types of cancers. Consequently, cancer researchers have chosen to […]
January 15, 2021

Virus Versus Virus: ‘ReScan’ Antibody Test is a Powerful New Tool

pandemics and epidemics, public health officials must identify individuals who are actively infected or have previously been infected, both to control the spread of disease and, in the case of vaccine-preventable illnesses, to prioritize individuals for vaccination. The SARS-CoV-2 pandemic has shone a bright light on the crucial need for […]
January 15, 2021

Blood test shows promise for early detection of acute heart transplant rejection

Researchers have developed a blood test that could make it possible for doctors to detect — then quickly prevent or slow down — acute heart transplant rejection, a potentially deadly condition that occurs in the early months after a patient has received a donor heart. They estimate that the test […]
January 15, 2021

Towards new methods for replacing animal testing

For many years, researchers at the National Food Institute, Technical University of Denmark have studied the harmful effects of chemicals and developed methods to best and most effectively investigate their harmful effects. Of the many thousands of chemical substances to which humans can be exposed, the majority has not been […]
January 15, 2021

Declining Resilience as a Manifestation of Aging

Resilience, meaning the ability to recover from wounds, infection, and other forms of damage, is more or less the flip side of frailty in aging. Frailty increases, resilience decreases. A damaged system is less robustly resilient to further damage, as reliability theory tells us. Degenerative aging is precisely an accumulation […]
January 15, 2021

Killing cancer by unleashing the body’s own immune system

The body’s immune system is the first line of defence against infections like bacteria, viruses or cancers. Some cancers, however, have developed the art of molecular deception to avoid destruction by the body’s immune system. However, a University of Missouri researcher might have found a new way to help the […]