Related Science News – Page 44 – Innovita Research

Related Science News

July 10, 2018

Novel drug therapy partially restores hearing in mice

A small-molecule drug is one of the first to preserve hearing in a mouse model of an inherited form of progressive human deafness, report investigators at the University of Iowa, Iowa City, and the National Institutes of Health’s National Institute on Deafness and Other Communication Disorders (NIDCD). The study, which […]
July 10, 2018

Gene therapy method developed to target damaged kidney cells

Gene therapy has gained momentum in the past year, following the federal government’s approval of the first such treatments for inherited retinal diseases and hard-to-treat leukemia. Now, research led by Washington University School of Medicine in St. Louis has shown, in mice, that genetic material can be delivered to damaged […]
July 9, 2018

Antibody identifier could speed development of therapies for cancer, other diseases

UCLA-led team created a model to predict effectiveness of potential treatments to help the immune system. A research team led by a UCLA bioengineer has developed a model to predict the extent to which new laboratory-designed antibodies will be able to combat specific human diseases. This is the first time […]
July 9, 2018

New Form Of Wound Healing Revealed By Parasitic Gut Worms

Experiments using parasitic worms in the mouse gut have revealed a surprising new form of wound repair, a finding that could help scientists develop ways to enhance the body’s natural healing abilities. Researchers have long believed that adult stem cells contribute to wound healing in tissues like the gut and […]
July 9, 2018

How CRISPR Tools are Unlocking New Ways to Fight Disease

Recent leaps in gene editing technology have brought ideas that just a decade ago seemed like science fiction to the cusp of reality. The already famous CRISPR system allows scientists to edit faulty genes by cutting and replacing sections of DNA, but new and improved CRISPR techniques have expanded CRISPR’s […]
July 9, 2018

Cell therapy is the future, and Wisconsin is the place, UW-Madison expert tells Technology Council

Medicine is rapidly approaching a great advance that will augment or replace drugs with human cells for treating a range of intractable conditions, an expert in cell therapy told the Wisconsin Technology Council. Jacques Galipeau, assistant dean for therapeutics discovery at the University of Wisconsin School of Medicine and Public […]
July 9, 2018

Researchers apply computing power to track the spread of cancer

This migration of cells can lead to metastatic disease, which causes about 90 percent of cancer deaths from solid tumors — masses of cells that grow in organs such as the breast, prostate or colon. Understanding the drivers of metastasis could lead to new treatments aimed at blocking the process […]
July 6, 2018

Positive Topline Results of the Final Analysis for BAN2401 for Treating Alzheimer's Disease Announced

Eisai Co., Ltd. and Biogen Inc. (NASDAQ: BIIB) announced positive topline results from the Phase II study with BAN2401, an anti-amyloid beta protofibril antibody, in 856 patients with early Alzheimer's disease. The study achieved statistical significance on key predefined endpoints evaluating efficacy at 18 months on slowing progression in Alzheimer's […]
July 5, 2018

Obesity affects prostate cancer test results

University of Adelaide research shows that the results of the most widely used test for prostate cancer may be affected by obesity. With increasing prevalence of obesity in high-income countries, this study published by the Society for Endocrinology, has important implications for detecting and monitoring the most common form of cancer […]
July 5, 2018

A Next-Gen EEG Could Help Bring Back Lost Brain Function

A device under development at the Department of Energy’s SLAC National Accelerator Laboratory and Stanford University could help bring back lost brain function by measuring how the brain responds to therapies that stimulate it with electric current. The approach could open new avenues for treating brain disorders and selectively switching […]
July 5, 2018

Wireless Pressure-Sensing Eye Implant Could Help Prevent Blindness

“By bringing together novel packaging and microelectronic technologies, and in close collaborations with ophthalmologists, we were able to design a miniaturized, fully wireless, and highly-sensitive sensor,” says Azita Emami, Caltech's Andrew and Peggy Cherng Professor of Electrical Engineering and Medical Engineering and a Heritage Medical Research Institute Investigator, and paper co-author. […]
July 4, 2018

Stem cells restore function in primate heart-failure study

Researchers at UW Medicine in Seattle have successfully used human stem cells to restore heart function in monkeys with heart failure. The findings suggest that the technique will be effective in patients with heart failure, the leading cause of death in the world. “The cells form new muscle that integrates […]
July 4, 2018

Research Brief: Eradicating cancer with immune cells armed with nanorings

Can we use nanotechnology to transform our own immune cells into cancer serial killers? Dr. Carston R. Wagner, professor and endowed chair of the Department of Medicinal Chemistry in the College of Pharmacy and Masonic Cancer Center member, has proven so by his team’s development of techniques that activate immune cells, specifically T-cells, to […]
July 3, 2018

Medical researchers, engineers look to nanovaccines to fight pancreatic cancer

While out mowing his carefully kept lawn during the summer and fall of 2012, a 75-year-old retiree noticed his lower back and side didn’t feel quite right. But it didn’t seem like the normal muscle tweak and spasms. So, when he went in for his annual physical that fall, he […]
July 3, 2018

Biochemists follow clues toward Alzheimer’s, cancer, longevity

James McNew’s and Michael Stern’s biochemical hunt for the root cause of a rare, paralyzing genetic disorder is a 10-year quest that’s taken an unexpected turn toward everyday killers such as Alzheimer’s disease, cancer and aging. The National Institutes of Health has awarded the Rice University scientists a five-year R01 grant to […]
July 3, 2018

Odds of living to 110-plus level out — once you hit 105

Want to be a supercentenarian? The chances of reaching the ripe old age of 110 are within reach – if you survive the perilous 90s and make it to 105 when death rates level out, according to a study of extremely old Italians led by UC Berkeley and Sapienza University […]
July 3, 2018

Neta to explore why aging brains stay on the sunny side

University of Nebraska–Lincoln psychologist Maital Neta aims to find out why people interpret ambiguous everyday events — are they whispering about me? — more favorably as they get older. Her research could one day help inform treatment options for depression, anxiety and similar maladies. Neta has earned a $756,611 Faculty Early Career […]
July 2, 2018

Loss of Cilia Leads to Melanoma

Most cells in the human body have a cilium, a slender cell protuberance that picks up signals from the cell's external environment. Researchers at the University of Zurich have now shown that these fine sensory antennae play a key role in the formation of melanoma. When cilia are prevented from […]
July 2, 2018

Immune Profile for Successful Cancer Immunotherapy Discovered

In a new study published online in Nature Medicine, UC San Francisco researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs known as checkpoint inhibitors. The findings, including initial observations from human tumor samples, mechanistic […]
July 2, 2018

Combination Therapy May Revive Prospects for ‘Embattled’ Breast Cancer Drugs

More than 60 percent of breast cancer cases involve defects in the same biochemical chain of events within cancer cells — known as the PI3 kinase (PI3K) pathway — but efforts to develop therapies targeting this pathway have met with little success after hundreds of mostly failed clinical trials. And […]
July 2, 2018

The Unbearable Sensation of Being: Living With Sensory Processing Disorder

Xander, while growing up in the perpetual sensory assault of Manhattan, had to get off the train any time someone with a guitar entered his subway car to play for small change. Cal had a more enigmatic reaction to stimuli. His mother, Jennifer, points to the floor-to-ceiling windows in her […]
July 2, 2018

Scientists discover a new mechanism that prevents the proliferation of cancer cells

Canadian researchers have discovered a new and direct molecular mechanism to stop cancer cells from proliferating. In the prestigious journal Nature Cell Biology, scientists from Université de Montréal show that a disruption of a fine balance in the composition of ribosomes (huge molecules that translate the genetic code into proteins) results […]
July 2, 2018

CAR-T Immunotherapies May Have a New Player

Emerging CAR-T immunotherapies leverage modified versions of patient’s T-cells to target and kill cancer cells. In a new study, published in Cell Stem Cell, researchers at University of California San Diego School of Medicine and University of Minnesota report that similarly modified natural killer (NK) cells derived from human induced pluripotent […]
July 2, 2018

A simpler, safer operation for treating kidney cancer

Many cases of early-stage kidney cancer can be treated with a relatively new, nonsurgical procedure used to destroy tumors, a study by a team led by Weill Cornell Medicine and NewYork-Presbyterian suggests. The procedure, called percutaneous ablation, involves the insertion of a needle through the skin into a kidney tumor, […]
June 29, 2018

A new tactic for starving tumors

A tumor’s goal is simple: to grow, grow, grow, by making more cancer cells. But that often means growing so fast that the oxygen supply gets scarce, at which point cells within the tumor start to suffocate. Without oxygen, these ever-dividing cells struggle to make enough aspartate, a crucial ingredient […]
June 29, 2018

Restricting a key cellular nutrient could slow tumor growth

Remove tumor cells from a living organism and place them in a dish, and they will multiply even faster than before. The mystery of why this is has long stumped cancer researchers, though many have simply focused on the mutations and chains of molecular reactions that could prompt such a […]
June 29, 2018

Men with aggressive prostate cancer may get new powerful drug option

Men with non-metastatic castrate-resistant prostate cancer and a quickly rising PSA level present a medical dilemma. The rising PSA (prostate-specific antigen) means there is cancer activity, but no visible metastasis in a scan. These men are receiving hormone treatments to reduce the testosterone on which their cancer feeds, but their cancers […]
June 29, 2018

Research on cancer-frying nanoparticles heats up

Need to kill tumors? Just add heat. That’s the promise of heated magnetic nanoparticles, a futuristic-sounding technology that could one day be used to fry and eradicate cancer cells without harming healthy tissue elsewhere in the body. New research led by the University at Buffalo advances this concept, with scientists […]
June 29, 2018

Smart Probe Detecting Cancer Cells May Improve Survival Rates

A new Tel Aviv University study explores a novel smart probe for image-guided surgery that may dramatically improve post-surgical outcomes for cancer patients. In many kinds of cancers, it is often not the primary malignant tumor, but rather metastasis — the spread of lingering cancer cells to other parts of the body […]
June 29, 2018

Patients could be spared life-long leukaemia treatment, clinical trial finds

People with a slow developing type of blood cancer may be able to safely come off  ‘life-long’ daily treatment in the future and remain free from cancer, the latest results from a University of Liverpool clinical trial suggest. Chronic myeloid leukaemia (CML) is diagnosed in around 600 people each year […]